Molecular Screening for Digital Dermatitis-Associated Treponemes in Bovine Ischaemic Teat Necrosis Lesions and Milk in Dairy Cattle [PDF]
PathogensBovine ischaemic teat necrosis (ITN) is a disease affecting the skin of the teats of dairy cows with an unknown aetiopathogenesis. Digital dermatitis (DD)-associated treponemes have previously been suggested as a potential aetiological agent in ITN ...
Hayley E Crosby-Durrani +2 more
exaly +4 more sources
Do Treponemes in Bovine Digital Dermatitis-Associated Claw Horn Lesions Preclude Co-Infection by Pyogenic Bacteria? [PDF]
MicroorganismsBovine digital dermatitis (BDD) is an infectious claw disease chiefly induced by treponemes, while deep digital sepsis (DDS) is caused by pyogenic bacteria.
Sabine Brandt +5 more
doaj +2 more sources
Red Blood Cell Lysis Pretreatment Can Significantly Improve the Yield of Treponema pallidum DNA from Blood [PDF]
Microbiology Spectrum, 2023 PCR can be a supplement to Treponema serological testing. However, its sensitivity is not satisfactory for blood sample testing. The aim of this study was to investigate whether pretreatment with red blood cell (RBC) lysis could enhance the yield of ...
Zi-Han Wei +5 more
doaj +2 more sources
Altered splenic T-cell subpopulation dynamics in a murine model of bovine digital dermatitis-associated Treponema spp. infection [PDF]
Frontiers in ImmunologyBovine digital dermatitis (BDD) is an infectious hoof disease associated with multiple Treponema species, causing significant economic and welfare concerns in the cattle industry.
Edeneil Jerome Valete +3 more
doaj +2 more sources
Successful implementation of a risk assessment and mitigation program to control bovine digital dermatitis at the herd-level [PDF]
Scientific ReportsThis nonrandomized clinical intervention study was designed as a prospective, multicenter group comparison to evaluate the efficacy of a risk assessment and mitigation program to control bovine digital dermatitis (BDD). The program was implemented over a
Jim Weber +11 more
doaj +2 more sources
Bovine Digital Dermatitis: Treponema spp. on trimming equipment and chutes – effect of washing and disinfection [PDF]
BMC Veterinary ResearchBackground Digital dermatitis (DD) is a contagious bovine foot disease causing reduced animal welfare and negative economic consequences for the farmer. Treponema spp. are the most important causative agents.
Lina Ahlén +6 more
doaj +2 more sources
Treponema pallidum induces pro-inflammatory cytokine secretion in macrophages and macrophage-endothelial co-cultures [PDF]
Frontiers in Cellular and Infection MicrobiologySyphilis, caused by the extracellular bacterium Treponema pallidum ssp. pallidum, is a multi-stage and systemic infection that is lifelong in the absence of treatment. Two host cell types that frequently encounter T.
Sean Waugh +4 more
doaj +2 more sources
Proteomic analysis of the Treponema pallidum subsp. pallidum SS14 strain: coverage and comparison with the Nichols strain proteome [PDF]
Frontiers in MicrobiologyIntroductionStrains of the syphilis spirochete, Treponema pallidum ssp. pallidum, group into one of two deep-branching clades: the Nichols clade or the globally dominant Street Strain 14 (SS14) clade. To date, in-depth proteome-wide analyses have focused
Simon Houston +4 more
doaj +2 more sources
Frontiers in Cellular and Infection Microbiology, 2021 Bovine digital dermatitis (BDD) is a common infectious disease of digital skin in cattle and an important cause of lameness worldwide, with limited treatment options.
Kerry Newbrook +3 more
doaj +1 more source
PLoS Pathogens, 2021 Here, we report the first complete genomes of three cultivable treponeme species from bovine digital dermatitis (DD) skin lesions, two comparative human treponemes, considered indistinguishable from bovine DD species, and a bovine gastrointestinal (GI ...
Gareth J Staton +9 more
doaj +1 more source