Results 11 to 20 of about 2,659 (174)

Genomic Insights Into the Treponema Genus: Taxonomic Resolution of Treponema vincentii and Description of Two Novel Species, Treponema plautii sp. nov. and Treponema sinense sp. nov. [PDF]

Mol Oral Microbiol
ABSTRACT Objectives Periodontal disease, a global health concern, is strongly associated with oral treponemes. However, the taxonomy of some species remains unresolved, hindering our understanding of their roles in disease. This study aims to clarify the taxonomy of three strains isolated from patients with periodontal disease using phylogenomic and ...
Fong JYH, Yeung ML, Li TT, Li WH, Ma Y, Zhao Y, Leung WK, Teng JLL.   +7 more
europepmc   +2 more sources

Bright New Resources for Syphilis Research: Genetically Encoded Fluorescent Tags for Treponema pallidum and Sf1Ep Cells. [PDF]

Mol Microbiol
By employing genetic engineering, Treponema pallidum was modified to express GFP, and Sf1Ep cells to express mCherry on the cytoplasmic membrane and BFP in the nucleus. These new resources for syphilis research will facilitate experimental designs to better define the complex interplay between T. pallidum and the host during infection.
Grillová L, Romeis E, Lieberman NAP, Tantalo LC, Xu LH, Molini B, Trejos AT, Lacey G, Goulding D, Thomson NR, Greninger AL, Giacani L.   +11 more
europepmc   +2 more sources

The occurrence of Treponema spp. in gingival plaque from dogs with varying degree of periodontal disease. [PDF]

PLoS ONE, 2018
Periodontal disease is common in dogs and is initiated by gingival plaque composed of several hundred bacterial species. Some of these species have specifically been pointed out as potential periodontal pathogens, such as Treponema spp.
Janna Nises, Anna Rosander, Ann Pettersson, Annette Backhans   +3 more
doaj   +1 more source

Diversity of Treponema denticola and Other Oral Treponeme Lineages in Subjects with Periodontitis and Gingivitis

Microbiology Spectrum, 2021
More than 75 species/species-level phylotypes belonging to the genus Treponema inhabit the human oral cavity. Treponema denticola is commonly associated with periodontal disease, but the etiological roles and ecological distributions of other oral ...
Huihui Zeng, Yuki Chan, Wenling Gao, W. Keung Leung, Rory M. Watt   +4 more
doaj   +1 more source

MyD88 deficiency markedly worsens tissue inflammation and bacterial clearance in mice infected with Treponema pallidum, the agent of syphilis. [PDF]

PLoS ONE, 2013
Research on syphilis, a sexually transmitted infection caused by the non-cultivatable spirochete Treponema pallidum, has been hampered by the lack of an inbred animal model.
Adam C Silver, Dana W Dunne, Caroline J Zeiss, Linda K Bockenstedt, Justin D Radolf, Juan C Salazar, Erol Fikrig   +6 more
doaj   +1 more source

Infectious disease in the Pleistocene: Old friends or old foes?

American Journal of Biological Anthropology, Volume 182, Issue 4, Page 513-531, December 2023., 2023
Sources of evidence for studying infectious diseases of humans and other Pleistocene hominins. From top to bottom: DNA analysis of humans and hominins, modern and ancient, including the analysis of genomes at a population scale; palaeopathology, such as osteolytic skeletal lesions resulting from infection, and the study of mummified tissues or palaeo ...
Charlotte J. Houldcroft, Simon Underdown
wiley   +1 more source

New putative periodontopathogens and periodontal health‐associated species: A systematic review and meta‐analysis

Journal of Periodontal Research, Volume 58, Issue 5, Page 893-906, October 2023., 2023
Abstract To investigate the existence of any association between new putative periodontal pathogens and periodontitis. Two independent reviewers conducted electronic literature searches in the MEDLINE (PubMed), EMBASE, DOSS and Google Scholar databases as well as a manual search to identify eligible clinical studies prior to November 2022.
Angéline Antezack, Damien Etchecopar‐Etchart, Bernard La Scola, Virginie Monnet‐Corti   +3 more
wiley   +1 more source

Endemic treponemal diseases [PDF]

Transactions of The Royal Society of Tropical Medicine and Hygiene, 2014
The endemic treponemal diseases, consisting of yaws, bejel (endemic syphilis) and pinta, are non-venereal infections closely related to syphilis, and are recognized by WHO as neglected tropical diseases (NTDs). Despite previous worldwide eradication efforts the prevalence of yaws has rebounded in recent years and the disease is now a major public ...
Marks, Michael, Solomon, Anthony W, Mabey, David C   +2 more
openaire   +5 more sources

High conservation of the dental plaque microbiome across populations with differing subsistence strategies and levels of market integration

Molecular Ecology, Volume 32, Issue 14, Page 3872-3891, July 2023., 2023
Abstract Industrialization—including urbanization, participation in the global food chain and consumption of heavily processed foods—is thought to drive substantial shifts in the human microbiome. While diet strongly influences stool microbiome composition, the influence of diet on the oral microbiome is largely speculative.
Irina M. Velsko, Sandrine Gallois, Raphaela Stahl, Amanda G. Henry, Christina Warinner   +4 more
wiley   +1 more source

First description of interdigital hyperplasia associated with contagious ovine digital dermatitis in two sheep

Frontiers in Veterinary Science, 2023
Interdigital hyperplasia (IH) is a fold of fibrous tissue protruding into the interdigital space that rarely occurs in sheep. Interdigital hyperplasia secondary infected with bovine digital dermatitis (BDD) treponemes has been reported in cattle in the ...
Maher Alsaaod, Robin Michael Schmid, Nathalie Zwahlen, Sara Soto, Nicole Wildi, Torsten Seuberlich, Adrian Steiner   +6 more
doaj   +1 more source