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Advances in the development and evaluation of bovine herpesvirus 1 vaccines

Veterinary Microbiology, 1996
This review deals with conventional and modern bovine herpesvirus 1 (BHV1) vaccines. Conventional vaccines are widely used to prevent clinical signs of infectious bovine rhinotracheitis. The use of conventional vaccines, however, does not appear to have resulted in reduction of the prevalence of infection.
J T Van Oirschot, M J Kaashoek, F A M Rijsewijk   +2 more
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Vaccination Trials Against Bovine Herpesvirus-1

Veterinary Research Communications, 2005
G. Castrucci1,∗, M. Ferrari2, D. Salvatori3, S. Sardonini4, F. Frigeri5, S. Petrini1, M. Lo Dico1, C. Marchini6, A. Rotola7, A. Amici6, M. Provinciali8, A. Tosini2, R. Angelini4 and E. Cassai7 1University of Perugina; 2Zooprophylaxis Institute, Brescia; 3Royal Veterinary College, London, UK; 4A.S.L.
CASTRUCCI G, FERRARI M, SALVATORI D, SARDONINI S, FRIGERI F, PETRINI S, LO DICO M, MARCHINI C, ROTOLA, Antonella, AMICI A, PROVINCIALI M, TOSINI A, ANGELINI R, CASSAI, Enzo   +13 more
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A vhs-like activity of bovine herpesvirus-1

Archives of Virology, 2000
Bovine herpesvirus 1 (BHV-1) is a major pathogen of cattle, causing significant disease including immunosuppression in infected animals. In vitro, the surface expression of major histocompatibility complex (MHC) class I molecules, crucial for an appropriate anti-viral immune response of the host, is down-regulated by BHV-1 infection.
S, Hinkley, A P, Ambagala, C J, Jones, S, Srikumaran   +3 more
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A comparative analysis of envelope and tegument proteins of suid herpesvirus 1, bovine herpesvirus 1 and bovine herpesvirus 5

Archives of Virology, 2010
The aim of this study was to analyze the disordered regions (DRs) in the envelope and tegument proteins of three closely related herpesviruses: bovine herpesvirus 1, bovine herpesvirus 5 and suid herpesvirus 1. Tegument proteins showed a greater percentage of DRs than the envelope proteins did.
A A, Fonseca, M B, Heinemann, R C, Leite, J K P, Reis   +3 more
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Protective effect of inactivated bovine herpesvirus-1 in calves experimentally infected with bovine herpesvirus-1 and Pasteurella haemolytica

Research in Veterinary Science, 1991
The protective effect of an inactivated whole-virion bovine herpesvirus-1 (BHV-1) immunising inoculum, without adjuvant, against viral-bacterial respiratory disease was studied in three experimental treatment groups of five calves each. One group was boosted 14 days after the first vaccination and at this time the second group received their initial ...
K W, Jericho, K G, Loewen, S E, Smithson, G C, Kozub   +3 more
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Genetic characterisation of bovine herpesvirus 1 in New Zealand

New Zealand Veterinary Journal, 2006
To genotype bovine herpesvirus type 1 (BHV-1) isolates from cattle in New Zealand.Twenty-eight BHV-1 isolates were collected from clinical samples from cattle over 28 years. They were characterised and compared using restriction endonuclease analysis (REA), and polymerase chain reaction (PCR) and DNA sequencing.Twenty-four isolates were classified as ...
G W Horner
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Bovine monoclonal antibodies specific for bovine herpesvirus-1 glycoprotein gIII

American Journal of Veterinary Research, 1990
SUMMARY Spleen cells from a calf immunized with bovine herpesvirus-1 (BHV-1) were fused with the nonsecreting murine cell line SP2/0. Several bovine-murine hybridomas secreting bovine immunoglobulins were stabilized. Of these, 9 hybridomas secreted bovine monoclonal antibodies that specifically bound to BHV-1 in a radioimmunoassay.
S, Srikumaran, D V, Onisk, T J, Zamb, F A, Osorio, D N, Rice   +4 more
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Isolation of bovine herpesvirus-1 from vesicular lesions of the bovine udder

American Journal of Veterinary Research, 1984
SUMMARY Bovine herpesvirus-1 was isolated from vesicular lesions on the udder and mammary papillae (teats) of a Charolais cow. Lesions on the animal consisted of papules and vesicles up to 10 mm in diameter. The virus was identified by fluorescent antibody and serum-neutralization tests.
J S, Guy, L N, Potgieter, M, McCracken, W, Martin   +3 more
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Analysis of bovine trigeminal ganglia following infection with bovine herpesvirus 1

Veterinary Microbiology, 2002
Following primary infection of the eye, oral cavity, and/or nasal cavity, bovine herpesvirus 1 (BHV-1) establishes latency in trigeminal ganglionic (TG) neurons. Virus reactivation and spread to other susceptible animals occur after natural or corticosteroid-induced stress.
M T C, Winkler, A, Doster, J H, Sur, C, Jones   +3 more
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Characteristics of live bovine herpesvirus-1 vaccines

The Veterinary Journal, 2005
The common disease caused by bovine herpes virus 1 infection is febrile rhinotracheitis (FRT) and under certain conditions the virus is strongly implicated in pre-disposing cattle to pneumonic pasteurellosis. These illnesses account for a significant economic loss in the cattle industry worldwide and vaccination is widely applied.
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