Results 101 to 110 of about 193,115 (271)

Progress in RNA‐Targeted Therapeutics for Human Diseases

MedComm, Volume 7, Issue 2, February 2026.
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang, Aimin Jiang, Bin‐Kui Jia, Yuming Jin, Yinghu Chen, Zhaoyu Li, Yan Liao, Haoling Zhang, Zhiheng Lin, Xiao Fang, Linhui Wang   +10 more
wiley   +1 more source

Detection of a novel gammaherpesvirus (genus Rhadinovirus) in wild muntjac deer in Northern Ireland [PDF]

, 2017
This study represents the initial part of an investigation into the potential for non-native, wild, free-living muntjac deer (Muntiacus reevesi) to carry viruses that could be a threat to livestock.
A Barlow, AI Ward, AJ Davison, Cheryl Ball, DR VanDevanter, E Cesarman, G Donofrio, GC Russell, Jaimie T. A. Dick, John McKillen, JTA Dick, K Tamura, K Yokoi, Kayleigh Hogg, Lisa Collins, M Kearse, MS Freeman, Neil Reid, Paula Lagan, RJ Putmam, RJ Putman, SF Altschul, Simon Doherty, T Passler, W Glawischnig   +24 more
core   +1 more source

The strong enhancer element in the immediate early region of the human cytomegalovirus genome [PDF]

, 1985
The human cytomegalovirus (HCMV), a member of the herpesvirus group, was found to possess a strong transcription enhancer in the immediate early gene region. Co-transfection of enhancerless SV40 DNA with randomly fragmented HCMV DNA yielded two SV40-
Boshart, Michael, Calendar, R., Dorsch-Häsler, Karoline, Fleckenstein, Bernhard, Gold, L., Jahn, Gerhard, Rüger, Rüdiger, Schaffner, Walter, Stoerker, Jay, Weber, Frank   +9 more
core   +1 more source

ETIOLOGICAL AND MOLECULAR BIOLOGICAL INVESTIGATION OF CAPRINE HERPESVIRUS 1 ISOLATED IN BULGARIA

Archives of Veterinary Medicine, 2009
From goat and bucks with genital disorders and abortions the attempts for isolation of caprine herpesvirus 1 (CHV 1) were carried out. For virus exaltation Dexametazone was used.
Raiko Peshev, Ivo Sirakov, Nedelcho Nedelchev, Stoil Karadzhov   +3 more
doaj   +1 more source

A Brazilian glycoprotein E-negative bovine herpesvirus type 1.2a (BHV-1.2a) mutant is attenuated for cattle and induces protection against wild-type virus challenge [PDF]

The authors previously reported the construction of a glycoprotein E-deleted (gE-) mutant of bovine herpesvirus type 1.2a (BHV-1.2a). This mutant, 265gE-, was designed as a vaccinal strain for differential vaccines, allowing the distinction between ...
Esteves, P.A., Flores, E.F., Franco, A.C., Lima, M., de, Rijsewijk, F.A.M., Roehe, P.M., Spilki, F.R., Weiblen, R.   +7 more
core   +1 more source

The extraordinary evolutionary history of the reticuloendotheliosis viruses [PDF]

, 2013
The reticuloendotheliosis viruses (REVs) comprise several closely related amphotropic retroviruses isolated from birds. These viruses exhibit several highly unusual characteristics that have not so far been adequately explained, including their extremely
A Katzourakis, A Katzourakis, A Stamatakis, AC van der Kuyl, AD Yoder, AL Hughes, AM Awad, AM Fadly, Anna Maria Niewiadomska, Bill Sugden, BR Burmester, C Feschotte, C Hertig, CG Ludford, CG Ludford, CN Dren, CN Dren, CN Dren, CR Parrish, CY Kang, CY Lin, DC Nickle, DH Huson, DH Ley, DJ McGeoch, DS Arathy, DW Trampel, E Prukner-Radovcic, EH Dearborn, F Abascal, F Rodriguez, FR Robinson, H Koyama, HC Carlson, HG Purchase, HM Koo, I Davidson, IS Diallo, IS Diallo, J Hanson, J Li, J Martin, JJ Solomon, JP Stoye, JP Vanderberg, JS McDougall, K Nyakatura, KA Schat, KM Moore, LA Terzian, LE Hayes, LJ Yu, LT Coggeshall, M Barbacid, M Garcia, MJ Peterson, MK Cook, ML Drew, MR Patel, MW Dimmic, MX Motha, N Ratnamohan, N Yuasa, P Singh, PE Miller, PS Paul, PS Sarma, Q Liu, R Crespo, R Gifford, R Isfort, RA Weiss, RB Franklin, RB Franklin, RJ Isfort, RL Witter, RL Witter, RL Witter, RM Corwin, Robert J. Gifford, SB Hitchner, SK Biswas, SL Kosakovsky Pond, T Barbosa, T Tadese, TJ Kim, TM Grimes, VN Kewalramani, W Trager, WG Conway, WH Cheng, Y Wang, Z Cheng, Z Cui, Z Yang, É Brumpt   +95 more
core   +3 more sources

Review: Risks of disease transmission through semen in cattle

Animal, 2018
The purpose of this paper is to review scientific evidence concerning pathogens that could potentially be transmitted via bovine semen. As a result of a careful analysis of the characteristics of infections that may cause transmission of disease through ...
M.D. Givens
doaj   +1 more source

Immune response to bovine herpes herpesvirus type 1 infections: virus-specific antibodies in sera from infected animals [PDF]

, 1985
James K. Collins, Ann Butcher, Cynthia A. Riegel   +2 more
openalex   +1 more source

Saccharomyces boulardii modulates and improves the immune response to Bovine Herpesvirus type 5 Vaccine [PDF]

, 2018
Talita Bandeira Roos, Luciana Farias da Costa de Ávila, R.T. Sturbelle, Fernando Leite, Geferson Fischer, Fábio Pereira Leivas Leite   +5 more
openalex   +1 more source

A Neutrophil-Derived Antiviral Protein - Induction-Requirements and Biological Properties [PDF]

, 1989
Polymorphonuclear neutrophilic granulocytes (PMN) have been implicated as playing a role in antiviral defense. In addition to having phagocytic and cytotoxic activities, PMN may produce an antiviral substance with interferon (IFN)-like activity.
Ohmann, H.Bielefeldt, Campos, M., Fitzpatrick, D.R., Rapin, N., Babiuk, L.A.   +4 more
core