Results 61 to 70 of about 920,082 (266)

Are all bovine herpesvirus-1 reproductive disease events vaccine-induced?

, 2016
Modified-live virus (MLV) bovine herpesvirus 1 (BHV-1) vaccines have been a major part of the program to the prevention of reproductive disease in cattle. However, their use (or misuse) continues to result in major abortion storms.
Clement, T., Chase, C. C. L., Gillette, B.   +2 more
core   +1 more source

Encephalitis Induced by Bovine Herpesvirus 5 and Protection by Prior Vaccination or Infection with Bovine Herpesvirus 1 [PDF]

Journal of Veterinary Diagnostic Investigation, 1999
Calves were intranasally challenged with bovine herpesvirus 5 (BHV5) and followed for the development of viral infection, clinical encephalitis, histologic lesions in the brain, and viral sequences in the trigeminal ganglia. Calves that were previously vaccinated with bovine herepesvirus 1 (BHV1, n = 4) or previously infected with BHV1 ( n = 5) or that
K E, Cascio, E B, Belknap, P C, Schultheiss, A D, Ames, J K, Collins   +4 more
openaire   +2 more sources

What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?

Biotechnology and Bioengineering, EarlyView.
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady, Nicholas Donohue, Alexandra Bogdanovic, Sharon Davin, Brian Glennon, Niall Barron, C. Mark Smales   +6 more
wiley   +1 more source

Determination of protection provided by two modified live bovine herpesvirus-1 vaccines against bovine herpesvirus-1 conjunctivitis in calves

, 2023
A study was performed in 2 phases to determine the ability of 2 different modified live (MLV) bovine herpesvirus-1 (BoHV-1)vaccines to protect against conjunctivitis caused by a recent field isolate of BoHV-1.
Walz, Paul H., Short, Thomas H., Scruggs, Daniel, Cortese, Victor S.   +3 more
core   +1 more source

Enhancing Adeno‐Associated Virus 2 Capsid Engineering Through Co‐Evolutionary Coupling

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Adeno‐associated virus (AAV) has emerged as a leading platform for gene therapy. However, to unlock the full potential, their manufacturing yields, stability, and efficacy must all be improved. Rational design is limited by poor predictability and the potential impact of mutations on multiple important vector properties.
Sirimar Laosinwattana, Yiwen Li, Braulio Carrillo Sanchez, Ayesha Khan, Paul A. Dalby   +4 more
wiley   +1 more source

Evaluation of a Commercial Vaccine to Protect Developing Fetuses from Natural Challenges with Bovine Viral Diarrhea Virus and Bovine Herpesvirus 1

, 2010
Fetal protection in heifers vaccinated with a modified-live vaccine (Express® FPS, Boehringer Ingelheim Vetmedica) was evaluated following sequential, prolonged field exposures to animals persistently infected (PI) with bovine viral diarrhea virus (BVDV)
Marley, M. S. D., Ensley, D., Joiner, K. S., Givens, M. D., Jones, C. A., Rodning, S. P.   +5 more
core   +1 more source

Antibody kinetics against tetanus toxoid before and after primary vaccination of foals

Equine Veterinary Journal, EarlyView.
Abstract Background Vaccination recommendations for foals against Clostridium tetani vary. Available studies assessing foal immune responses, maternal antibody interference, or individual variation often used small foal numbers. Objectives To quantify antibody responses after tetanus vaccination in foals and explore associations with passively ...
Katharina Olbrich, Monica Venner, Bettina Wagner   +2 more
wiley   +1 more source

A Brazilian glycoprotein E-negative bovine herpesvirus type 1.2a (BHV-1.2a) mutant is attenuated for cattle and induces protection against wild-type virus challenge [PDF]

, 2002
The authors previously reported the construction of a glycoprotein E-deleted (gE-) mutant of bovine herpesvirus type 1.2a (BHV-1.2a). This mutant, 265gE-, was designed as a vaccinal strain for differential vaccines, allowing the distinction between ...
Esteves, P.A., Lima, M., de, Rijsewijk, F.A.M., Franco, A.C., Flores, E.F., Weiblen, R., Roehe, P.M., Spilki, F.R.   +7 more
core  

Inhibition of Bovine Herpesvirus 1 and Bovine Viral Diarrhea Virus Replication by Genistein: a Compound in Soybeans

, 2001
Bovine herpesvirus type 1 (BHV-1, IBR), an alphaherpesvirus, and bovine viral diarrhea virus (BVDV), a pestivirus, are important cattle pathogens. Genistein, a naturally occurring flavonoid in soybeans, inhibits in vitro replication of herpes simplex ...
Peterson, D., Wang, C. Y., Braun, L. J., El-Sheikh, A. A., Chase, C. C. L., Shaw, A.   +5 more
core   +1 more source

Importance of Viral Disease in Dairy Cow Fertility

Engineering, 2020
Many viral diseases are endemic in cattle populations worldwide. The ability of many viruses to cross the placenta and cause abortions and fetal malformations is well understood.
D. Claire Wathes, Chike F. Oguejiofor, Carole Thomas, Zhangrui Cheng   +3 more
doaj   +1 more source