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Advances in the development and evaluation of bovine herpesvirus 1 vaccines

open access: yesVeterinary Microbiology, 1996
This review deals with conventional and modern bovine herpesvirus 1 (BHV1) vaccines. Conventional vaccines are widely used to prevent clinical signs of infectious bovine rhinotracheitis. The use of conventional vaccines, however, does not appear to have resulted in reduction of the prevalence of infection.
J T Van Oirschot   +2 more
exaly   +4 more sources
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Vaccination Trials Against Bovine Herpesvirus-1

Veterinary Research Communications, 2005
G. Castrucci1,∗, M. Ferrari2, D. Salvatori3, S. Sardonini4, F. Frigeri5, S. Petrini1, M. Lo Dico1, C. Marchini6, A. Rotola7, A. Amici6, M. Provinciali8, A. Tosini2, R. Angelini4 and E. Cassai7 1University of Perugina; 2Zooprophylaxis Institute, Brescia; 3Royal Veterinary College, London, UK; 4A.S.L.
CASTRUCCI G   +13 more
openaire   +4 more sources

A vhs-like activity of bovine herpesvirus-1

Archives of Virology, 2000
Bovine herpesvirus 1 (BHV-1) is a major pathogen of cattle, causing significant disease including immunosuppression in infected animals. In vitro, the surface expression of major histocompatibility complex (MHC) class I molecules, crucial for an appropriate anti-viral immune response of the host, is down-regulated by BHV-1 infection.
S, Hinkley   +3 more
openaire   +2 more sources

Protective effect of inactivated bovine herpesvirus-1 in calves experimentally infected with bovine herpesvirus-1 and Pasteurella haemolytica

Research in Veterinary Science, 1991
The protective effect of an inactivated whole-virion bovine herpesvirus-1 (BHV-1) immunising inoculum, without adjuvant, against viral-bacterial respiratory disease was studied in three experimental treatment groups of five calves each. One group was boosted 14 days after the first vaccination and at this time the second group received their initial ...
K W, Jericho   +3 more
openaire   +2 more sources

Bovine monoclonal antibodies specific for bovine herpesvirus-1 glycoprotein gIII

American Journal of Veterinary Research, 1990
SUMMARY Spleen cells from a calf immunized with bovine herpesvirus-1 (BHV-1) were fused with the nonsecreting murine cell line SP2/0. Several bovine-murine hybridomas secreting bovine immunoglobulins were stabilized. Of these, 9 hybridomas secreted bovine monoclonal antibodies that specifically bound to BHV-1 in a radioimmunoassay.
S, Srikumaran   +4 more
openaire   +2 more sources

Isolation of bovine herpesvirus-1 from vesicular lesions of the bovine udder

American Journal of Veterinary Research, 1984
SUMMARY Bovine herpesvirus-1 was isolated from vesicular lesions on the udder and mammary papillae (teats) of a Charolais cow. Lesions on the animal consisted of papules and vesicles up to 10 mm in diameter. The virus was identified by fluorescent antibody and serum-neutralization tests.
J S, Guy   +3 more
openaire   +2 more sources

Analysis of bovine trigeminal ganglia following infection with bovine herpesvirus 1

Veterinary Microbiology, 2002
Following primary infection of the eye, oral cavity, and/or nasal cavity, bovine herpesvirus 1 (BHV-1) establishes latency in trigeminal ganglionic (TG) neurons. Virus reactivation and spread to other susceptible animals occur after natural or corticosteroid-induced stress.
M T C, Winkler   +3 more
openaire   +2 more sources

Characteristics of live bovine herpesvirus-1 vaccines

The Veterinary Journal, 2005
The common disease caused by bovine herpes virus 1 infection is febrile rhinotracheitis (FRT) and under certain conditions the virus is strongly implicated in pre-disposing cattle to pneumonic pasteurellosis. These illnesses account for a significant economic loss in the cattle industry worldwide and vaccination is widely applied.
openaire   +2 more sources

Detection of bovine herpesvirus-1 in bovine semen by a nested PCR assay

Journal of Virological Methods, 1993
A nested PCR assay targeting a portion of the glycoprotein IV gene has been developed for the detection of Bovine Herpesvirus-1 (BHV-1). Rapid and sensitive detection of the PCR products was achieved using a nonisotopic reverse dot-blot format with a visible color readout. Cross-reactivity of this PCR assay was not observed with the closely related BHV-
M, Wiedmann   +4 more
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Effects of immunization with bovine herpesvirus-1 glycoproteins on bovine herpesvirus-1-induced alteration of bovine neutrophil chemotactic and anti-Pasteurella haemolytica activities

Vaccine, 1988
It has been reported previously that active bovine herpesvirus-1 (BHV-1) infection greatly enhances the susceptibility of cattle to secondary bacterial pneumonia involving Pasteurella haemolytica. The present study examines the possibility that immunization of BHV-1 naive calves with purified BHV-1 glycoproteins would protect them against changes in ...
E J, Noel   +3 more
openaire   +2 more sources

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