Results 81 to 90 of about 163,541 (220)

Bovine Transcription Factor POU Class 2 Homeobox 1 (POU2F1/Oct1) Protein Promotes BoHV-1 Replication in MDBK Cells

open access: yesViruses
Bovine herpesvirus type 1 (BoHV-1) causes severe diseases in bovine species and great economic burden to the cattle industry worldwide. Due to its complex life cycle, many host factors that affect BoHV-1 replication remain to be explored.
Enguang Rong   +3 more
doaj   +1 more source

Progress in RNA‐Targeted Therapeutics for Human Diseases

open access: yesMedComm, Volume 7, Issue 2, February 2026.
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang   +10 more
wiley   +1 more source

Characterization of a continuous feline mammary epithelial cell line susceptible to feline epitheliotropic viruses. [PDF]

open access: yes, 2009
Mucosal epithelial cells are the primary targets for many common viral pathogens of cats. Viral infection of epithelia can damage or disrupt the epithelial barrier that protects underlying tissues.
Heymer, Anna   +8 more
core  

The Transcriptional Landscape of Marek’s Disease Virus in Primary Chicken B Cells Reveals Novel Splice Variants and Genes [PDF]

open access: yes, 2019
Marek’s disease virus (MDV) is an oncogenic alphaherpesvirus that infects chickens and poses a serious threat to poultry health. In infected animals, MDV efficiently replicates in B cells in various lymphoid organs.
Bertzbach, Luca D.   +7 more
core   +2 more sources

Differential regulation of translational stress responses by herpesvirus ubiquitin deconjugases

open access: yesThe FEBS Journal, Volume 293, Issue 4, Page 1024-1044, February 2026.
Translating viral mRNAs is challenging due to structural features that may slow translation or induce ribosome stalling. The viral ubiquitin deconjugases encoded by human pathogenic herpesviruses regulate the cellular response to ribosomal stress by inhibiting various branches of the Ribosomal Quality Control (RQC) and activating Ribosomal Stress ...
Jiangnan Liu   +3 more
wiley   +1 more source

Seroepidemiology of bovine herpesvirus‐1 in goats in south‐western Iran

open access: yesVeterinary Medicine and Science
Background Widely regarded as one of the chief causes of diseases in cattle population, bovine herpesvirus‐1 (BoHV‐1) has the potential to infect sheep and goat, making them potential reservoirs or hosts for this virus.
Mahdi Pourmahdi Borujeni   +3 more
doaj   +1 more source

Detection of a novel gammaherpesvirus (genus Rhadinovirus) in wild muntjac deer in Northern Ireland [PDF]

open access: yes, 2017
This study represents the initial part of an investigation into the potential for non-native, wild, free-living muntjac deer (Muntiacus reevesi) to carry viruses that could be a threat to livestock.
A Barlow   +24 more
core   +1 more source

Unraveling Network Pharmacology‐Based Therapeutics of Anthranilate Sulfonamides via Sirtuins/FOXO3a Cascade in Alzheimer's Disease

open access: yesJournal of Neurochemistry, Volume 170, Issue 2, February 2026.
Anthranilates sulfonamides (SA1–4) showed neuroprotective activity against human neuronal SH‐SY5Y cells under oxidative stress. The data represented significantly regulated sirtuins (SIRTs)/forkhead box class O 3a (FOXO3a)‐mediated longevity signaling pathway via targeting endogenous antioxidant enzymes, including superoxide dismutase 2 (SOD2) and ...
Waralee Ruankham   +7 more
wiley   +1 more source

Impact of BoLA‐DRB3 Polymorphisms on Clonality of Bovine Leukaemia Virus‐Infected Cells of Cattle With Lymphoma

open access: yesHLA, Volume 107, Issue 2, February 2026.
ABSTRACT Bovine leukaemia virus (BLV) infects cattle, integrates into the host genome as a provirus, and induces a persistent infection that remains asymptomatic but can cause leukaemia/lymphoma. Most BLV‐infected cell clones are created by massive depletion, and a few of these infected cell clones expand through the mitotic cycle, leading to the onset
Noriko Fukushi   +10 more
wiley   +1 more source

Co-infection with bovine herpesvirus type 1 and bovine leukemia virus in dairy cattle in cajamarca, peru: A seroprevalence study [PDF]

open access: yesIraqi Journal of Veterinary Sciences
Bovine herpesvirus type 1 (BoHV-1) and bovine leukemia virus (BLV) are among the most important pathogens affecting dairy cattle, causing significant economic losses worldwide.
MEDALI CUEVA RODRIGUEZ   +10 more
doaj   +1 more source

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