Results 161 to 170 of about 113,938 (312)

Fabp5 Is the Key Regulator Mediating γ‐CEHC Differentiation in Osteoblasts and Osteoclasts

open access: yesBioFactors, Volume 52, Issue 1, January/February 2026.
γ‐CEHC, as a natural Fabp5 inhibitor, ameliorates the osteoporotic microenvironment through a triple‐action mechanism—targeting Fabp5 inhibition → modulating macrophage polarization → balancing bone metabolism—highlighting its translational medical value.
Cheng Cheng   +7 more
wiley   +1 more source

A Novel MPT‐Driven Necrosis‐Related lncRNA Signature for Prognostic Prediction in Hepatocellular Carcinoma: Validation Using Organoids

open access: yesCancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background Mitochondrial permeability transition (MPT)‐driven necrosis, a recently identified form of programmed cell death, significantly influences tumor progression, therapy response, and prognosis. However, research on mitochondrial permeability transition‐driven necrosis‐related long non‐coding ribonucleic acids (MPTDNRlncRNAs) in ...
Yang Liu   +13 more
wiley   +1 more source

Purification and characterization of a protein-tyrosine kinase encoded by the Abelson murine leukemia virus [PDF]

open access: yes, 1985
Sequences termed v-abl, which encode the protein-tyrosine kinase activity of Abelson murine leukemia virus, have been expressed in Escherichia coli as a fusion product (ptabl50 kinase).
Baltimore, David   +4 more
core  

Prolonged persistence of tissue‐resident memory cells in the upper airway following SARS‐CoV‐2 infection and vaccination

open access: yesClinical &Translational Immunology, Volume 15, Issue 1, 2026.
In this study, we found that both SARS‐CoV‐2 infection and vaccination elicit long‐lived tissue‐resident immune responses in the nasopharynx (NP), marked by persistent TRM and BRM cells. Our experiment data determine that subjects with breakthrough infections exhibit significantly enhanced frequencies and polyfunctionality of CD4+ TRM cells, along with
Hyunkyung Cha   +7 more
wiley   +1 more source

Phosphorylation of bovine leukemia virus Tax protein is required for in vitro transformation but not for transactivation [PDF]

open access: bronze, 1998
Luc Willems   +14 more
openalex   +1 more source

Targeted demethylation of the BRD7 promoter based on CRISPR/dCas9 system inhibits the malignant progression of nasopharyngeal carcinoma

open access: yesClinical and Translational Medicine, Volume 16, Issue 1, January 2026.
1. Hypermethylation of BRD7 promoter CpG island is a critical mechanism leading to the downregulation of BRD7 expression in nasopharyngeal carcinoma (NPC). 2. LentiCRISPRv2/dCas9‐TET1CD‐sgRNAs demethylation system could promote transcriptional activation and expression of BRD7 by reducing its methylation. 3.
Jianxia Wei   +13 more
wiley   +1 more source

Tet2 deficiency promotes IgG1+ B‐cell expansion and differentiation blockade through deregulation of the Nfkbia–c‐Rel axis

open access: yesHemaSphere, Volume 10, Issue 1, January 2026.
Abstract The germinal center (GC) reaction is essential for orchestrating humoral immunity by producing plasma cells (PCs) and memory B cells (MBCs). TET2, an α‐ketoglutarate‐dependent dioxygenase, plays a critical role in B‐cell exit from the GC and in plasma cell differentiation.
Hussein Ghamlouch   +15 more
wiley   +1 more source

In vivo infection of sheep by bovine leukemia virus mutants [PDF]

open access: bronze, 1993
Isabelle Schwartz‐Cornil   +8 more
openalex   +1 more source

Cytomegalovirus IL‐10 in Plasma as a Marker of Active Infection in Allogeneic Hematopoietic Transplant Recipients: An Exploratory Study

open access: yesJournal of Medical Virology, Volume 98, Issue 1, January 2026.
ABSTRACT We investigated whether plasma cytomegalovirus (CMV) IL‐10 (cmvIL‐10) levels could serve as a biomarker of active CMV replication in allogeneic hematopoietic transplant recipients (allo‐HCT) in the presence or absence of letermovir (LMV) prophylaxis. A total of 189 leftover plasma samples that tested positive for CMV DNA (Alinity m CMV assay),
Ángela Sánchez‐Simarro   +7 more
wiley   +1 more source

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