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Interaction between Bovine leukemia virus (BLV) infection and age on telomerase misregulation

Veterinary Research Communications, 2015
Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leukosis (EBL). BLV can interact with telomerase and inhibits telomere shortening, contributing in leukemogenesis and tumour induction. The role of telomerase in BLV-induced lymphosarcoma and aging has been extensively studied.
Hemmatzadeh, F.   +8 more
openaire   +3 more sources

In vivo inhibition of bovine leukemia virus (BLV) expression.

Leukemia, 1989
Bovine leukemia virus-infected sheep were demonstrated to possess a plasma factor that specifically suppresses in vitro virus expression in lymphocyte cultures. This blocking activity is observed even after phytohemagglutinin (PHA) stimulation and is independent of cellular proliferation.
Schwartz-Cornil, Isabelle   +2 more
openaire   +2 more sources

Humoral and cellular responses in calves experimentally infected with Bovine Leukemia Virus (BLV)

Veterinary Immunology and Immunopathology, 1985
In order to elucidate whether infection by Bovine Leukemia Virus (BLV) might induce an immunodeficient state, we inoculated sixteen calves with BLV. The calves were followed up for two years and were tested for humoral and cellular responses using various parameters, namely the appearance of antibodies to the BLV antigens, the changes in the numbers of
R, Meiron   +4 more
openaire   +2 more sources

Glycoprotein and protein composition of bovine leukemia virus (BLV).

Neoplasma, 1981
Highly purified preparation of bovine leukemia virus (BLV) was obtained by the method described in this communication. BLV was isolated from cell-free culture medium, harvested from BLV-producing cell-line FLK. Polyacrylamide gel electrophoresis of BLV proteins and glycoproteins, in comparison with avian myeloblastosis virus (AMV), confirmed high ...
J, Prachar, K, Hlubinová
openaire   +1 more source

Bovine Leukemia Virus (BLV) & Lymphoma

Bovine Leukemia Virus (BLV), a lifelong retroviral infection in cattle that can reduce productivity and cause economic losses. Most infected cattle show no signs but can spread the virus within a herd. A portion develop persistent lymphocytosis, and 1–5% progress to lymphoma, usually in adult cattle. BLV is widespread in U.S.
openaire   +1 more source

Recent studies on the characterization of the bovine leukemia virus (BLV); development of new methods for the diagnosis of BLV infection

Veterinary Microbiology, 1976
Abstract In this report data presented show that the bovine leukemia virus (BLV) is infectious for cells of various species including humans. Bat monolayer cell cultures were the most permissive for replication of BLV and provided an abundant source of virus for characterization studies.
J.F. Ferrer   +7 more
openaire   +1 more source

Levels and role of cytokines in bovine leukemia virus (BLV) infection.

Leukemia, 1997
Bovine leukemia virus belongs to a small subfamily of exogenous retroviruses that includes the human retroviruses HTLV-1, HTLV-II and the simian virus, STLV-1. Like other retroviruses, infection with BLV results in deregulation of the host immune system at both humoral and cellular levels.
R, Meirom   +4 more
openaire   +1 more source

Blood dendritic cells in cattle infected with bovine leukemia virus (BLV): isolation and phenotyping

Polish Journal of Veterinary Sciences, 2012
AbstractDendritic cells (DCs) are most potent antigen presenting cells (APCs) with unique ability to prime effective immune responses. They express higher levels of MHC class II and accesory molecules on their surface, than other professional APCs. The investigations were performed on DCs generated from blood with the use of microbeads magnetically ...
M, Szczotka   +4 more
openaire   +2 more sources

Current status of Bovine Leukemia Virus (BLV) infection in Turkey

1996
Bovine Leukemia Virus (BLV) infection is common in the world. This infection has also been in Turkey since 1942. Between the years of 1991 and 1994, 941 cattle over the age of six months were investigated using commercially prepared kits for anti-BLV antibodies by ELISA in the Bursa Region of Turkey.
Batmaz, HASAN   +4 more
openaire   +1 more source

The improvement of monitoring methods of cattle infection with bovine leukemia virus (BLV).

Polish journal of veterinary sciences, 2003
This study demonstrates the usefulness of PLA and nested-PCR methods for the detection of cattle infection with enzootic bovine leukemia virus. Serological control with PLA was by 1.7% more sensitive than reference ELISA examination. Both the DNA of env-BLV gene in NCR, V-NCR, FLK and in recombinated AG clone cells, as well as in the whole blood and in
J, Rułka   +4 more
openaire   +1 more source

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