HTLV-1 Proviral Load in Vaginal Fluid Correlates with Levels in Peripheral Blood Mononuclear Cells [PDF]
Pathogens, 2023 Background: The prevalence of human T-lymphotropic virus type-1 (HTLV-1) infection is higher in women, and sexual intercourse has been described as an important route of male-to-female transmission.
Alisson de Aquino Firmino +8 more
doaj +2 more sources
Dolutegravir use is related to lower HTLV-1 proviral load in people co-infected by HIV-1 [PDF]
Communications MedicineBackground Infection by human T-cell lymphotropic virus type 1 (HTLV-1) affects millions of people worldwide and causes severe diseases. To date, no specific treatment is available for HTLV infection. The purpose of this study was to determine the impact
Tatiana Fernandez +4 more
doaj +2 more sources
Evaluation of bovine leukaemia virus infection control measures in Japanese Black beef cattle breeding farms: A 7-year longitudinal study based on proviral load. [PDF]
Vet Rec OpenAbstract Background Bovine leukaemia virus (BLV) infection remains a major problem for Japanese Black (Wagyu) cattle, and effective and sustainable control measures are essential to prevent its spread in breeding herds. This study aimed to monitor the BLV infection status of all cattle at a Japanese Black breeding farm in Kagoshima Prefecture, Japan ...
Kajisa M +9 more
europepmc +2 more sources
The SAMHD1 rs6029941 (A/G) Polymorphism Seems to Influence the HTLV-1 Proviral Load and IFN-Alpha Levels [PDF]
Frontiers in Cellular and Infection Microbiology, 2020 SAMHD1, a host dNTPase, acts as a retroviral restriction factor by degrading the pool of nucleotides available for the initial reverse transcription of retroviruses, including HTLV-1.
Maria Alice Freitas Queiroz +7 more
doaj +2 more sources
IL-10 predicts incident neuroinflammatory disease and proviral load dynamics in a large Brazilian cohort of people living with human T-lymphotropic virus type 1 [PDF]
Frontiers in ImmunologyHuman T-Lymphotropic Virus type-1 (HTLV-1) is a unique retrovirus associated with both leukemogenesis and a specific neuroinflammatory condition known as HTLV-1-Associated Myelopathy (HAM).
Tatiane Assone +21 more
doaj +2 more sources
Journal of Dairy Science: The objective was to evaluate the effects of bovine leukemia virus (BLV) infection, as determined by BLV seropositivity and proviral load, on 305-d milk, fat, and protein production of dairy cows.
Sulav Shrestha +5 more
doaj +3 more sources
Relevance of HTLV-1 proviral load in asymptomatic and symptomatic patients living in endemic and non-endemic areas of Argentina. [PDF]
PLoS ONE, 2019 HTLV-1 proviral load (pVL) in peripheral blood mononuclear cell (PBMCs) is proposed as a marker of disease progression but its role still remains controversial.
María Verónica Pineda +11 more
doaj +2 more sources
HTLV-1 integration into transcriptionally active genomic regions is associated with proviral expression and with HAM/TSP. [PDF]
PLoS Pathogens, 2008 Human T-lymphotropic virus type 1 (HTLV-1) causes leukaemia or chronic inflammatory disease in approximately 5% of infected hosts. The level of proviral expression of HTLV-1 differs significantly among infected people, even at the same proviral load ...
Kiran N Meekings +4 more
doaj +1 more source
Association between bovine leukemia virus proviral load and severity of clinical mastitis [PDF]
Journal of Veterinary Medical Science, 2019 Aiko Watanabe +2 more
exaly +2 more sources
Administration of a Toll-like receptor 9 agonist decreases the proviral reservoir in virologically suppressed HIV-infected patients. [PDF]
PLoS ONE, 2013 Toll-like receptor (TLR) agonists can reactivate HIV from latently infected cells in vitro. We aimed to investigate the TLR-9 agonist, CPG 7909's in vivo effect on the proviral HIV reservoir and HIV-specific immunity.
Anni A Winckelmann +8 more
doaj +1 more source