Results 31 to 40 of about 10,657 (203)

Plasma proteome analysis in HTLV-1-associated myelopathy/tropical spastic paraparesis [PDF]

, 2011
Background: Human T lymphotropic virus Type 1 (HTLV-1) causes a chronic inflammatory disease of the central nervous system known as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM) which resembles chronic spinal forms of multiple ...
Stumpf, M. P. H. (Michael P. H.), Aviva Witkover, Bangham, Charles RM, Kirk, Paul, Taylor, Graham P, Kirk Paul DW, Lewin Alexandra M, Kirk, Paul DW, Bangham Charles RM, Bangham, C. R. M. (Charles R. M.), Taylor, G. P. (Graham P.), Lewin, Alexandra M, Courtney, A, Kirk, PDW, Richardson, Sylvia, Wait Robin, Witkover, A, Lewin, Alexandra M., Alan Courtney, Robin Wait, Graham P Taylor, Courtney Alan, Michael PH Stumpf, Charles RM Bangham, Witkover Aviva, Witkover, Aviva, Wait, R, Paul DW Kirk, Wait, Robin, Richardson, S, Taylor Graham P, Bangham, CRM, Courtney, Alan, Bangham, CR, Richardson Sylvia, Stumpf, MP, Sylvia Richardson, Stumpf, Michael PH, Kirk, PD, Stumpf, MPH, Taylor, GP, Stumpf Michael PH, Alexandra M Lewin, Lewin, AM   +43 more
core   +1 more source

Neurologic, clinical, and immunologic features in a cohort of HTLV-1 carriers with high proviral loads [PDF]

Journal of NeuroVirology, 2020
AbstractA high proviral load (PVL) is recognized as a risk factor for human T cell leukemia virus-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), but there is a lack of prospective studies evaluating whether or not HTLV-1 carriers with high PVL are at risk of developing HAM/TSP or other HTLV-1-related diseases.
Sheila N. Ferraz, Gabriela F. Costa, José Abraão Carneiro Neto, Thiago Hebert, Cassius J. V. de Oliveira, Mariele Guerra, Lívia M. A. Oliveira, Edgar M. Carvalho   +7 more
openaire   +2 more sources

Economic losses associated with mastitis due to bovine leukemia virus infection

Journal of Dairy Science, 2023
: Bovine leukemia virus (BLV), which causes enzootic bovine leukosis and immunosuppression, is widely prevalent on Japanese dairy farms. However, in the absence of a national eradication scheme with compensation programs, it is important to estimate BLV ...
S. Nakada, Y. Fujimoto, J. Kohara, K. Makita   +3 more
doaj   +1 more source

BET Inhibitor JQ1 Attenuates Feline Leukemia Virus DNA, Provirus, and Antigen Production in Domestic Cat Cell Lines

Viruses, 2023
Feline leukemia virus (FeLV) is a cosmopolitan gammaretrovirus that causes lifelong infections and fatal diseases, including leukemias, lymphomas, immunodeficiencies, and anemias, in domestic and wild felids.
Garrick M. Moll, Cheryl L. Swenson, Vilma Yuzbasiyan-Gurkan   +2 more
doaj   +1 more source

High prevalence of skin disorders among HTLV-1 infected individuals independent of clinical status. [PDF]

PLoS Neglected Tropical Diseases, 2013
BackgroundHuman T-cell lymphotropic virus type 1 (HTLV-1) infection can increase the risk of developing skin disorders. This study evaluated the correlation between HTLV-1 proviral load and CD4(+) and CD8(+) T cells count among HTLV-1 infected ...
Renata Okajima, Augusto C P Oliveira, Jerusa Smid, Jorge Casseb, Jose Antonio Sanches   +4 more
doaj   +1 more source

Influence of INF-gamma gene polymorphism in HTLV-1 proviral load [PDF]

Retrovirology, 2011
Background Interferon-gamma (INF-g) is a key cytokine involved in the defense against intracellular pathogens, such as HTLV-1, by coordinating the expression of immunologically relevant genes. Previous studies showed the importance of this cytokine on HTLV-1-related pathogenesis.
Takayanagui Oswaldo M, Wagatsuma Virgínia M D, Cilião-Alves Daiani C, Rocha–Junior Maurício C, Haddad Rodrigo, Donadi Eduardo A, Covas Dimas T, Kashima Simone   +7 more
openaire   +2 more sources

Early events following bovine leukaemia virus infection in calves with different alleles of the major histocompatibility complex  DRB3 gene

Veterinary Research, 2020
Cattle maintaining a low proviral load (LPL) status after bovine leukaemia virus (BLV) infection have been recognized as BLV controllers and non-transmitters to uninfected cattle in experimental and natural conditions.
Agustina Forletti, Claudia María Lützelschwab, Rosana Cepeda, Eduardo N. Esteban, Silvina Elena Gutiérrez   +4 more
doaj   +1 more source

Quantification of the virus-host interaction in human T lymphotropic virus I infection

Retrovirology, 2005
Background HTLV-I causes the disabling inflammatory disease HAM/TSP: there is no vaccine, no satisfactory treatment and no means of assessing the risk of disease or prognosis in infected people. Like many immunopathological diseases with a viral etiology
Taylor Graham P, Tanaka Yuetsu, Heaps Adrian, Mosley Angelina J, Asquith Becca, McLean Angela R, Bangham Charles RM   +6 more
doaj   +1 more source

Evaluation of real time PCR technique to diagnosis of human T-lymphotropic virus type I (HTLV-I) in patients in the Hematologia da Fundação Hemope Hospital, in Northeastern Brazil Avaliação da técnica de PCR em tempo real para o diagnóstico do virus linfotrópico tipo I de células T humana (HTLV-I) em pacientes do Hospital de Hematologia da Fundação Hemope, no Nordeste do Brasil

Revista Brasileira de Hematologia e Hemoterapia, 2008
As a high degree of homology exists between the proviral genomes of HTLV-I and HTLV-II, there is significant cross-reactivity. Therefore although detection of HTLV antibodies is characteristic of viral infection, it is not sufficient to confirm the ...
Bruna C. Arruda, Rodrigo A. Lira, Paula Loureiro, Lucas Brandão, Paulo Souza, Wayner V. Souza, Yara M. Gomes   +6 more
doaj   +1 more source

New evidence of bovine leukemia virus circulating in Myanmar cattle through epidemiological and molecular characterization.

PLoS ONE, 2020
Bovine leukemia virus (BLV) is the etiological agent of enzootic bovine leukosis, which is the most common neoplastic disease of cattle. BLV infects cattle worldwide and causes serious problems for the cattle industry.
Kyaw Kyaw Moe, Meripet Polat, Liushiqi Borjigin, Ryosuke Matsuura, Si Thu Hein, Hla Hla Moe, Yoko Aida   +6 more
doaj   +1 more source