Results 21 to 30 of about 10,657 (203)

Feline Leukemia Virus p27 Antigen Concentration and Proviral DNA Load Are Associated with Survival in Naturally Infected Cats

Viruses, 2021
Longitudinal studies of cats naturally infected with feline leukemia virus (FeLV) are important for understanding disease outcomes. Levels of p27 antigen and copy numbers of proviral DNA have been associated with FeLV-infection courses.
Melissa J. Beall, Jesse Buch, Genevieve Clark, Marko Estrada, Andrei Rakitin, Natascha T. Hamman, Monica K. Frenden, Ellen P. Jefferson, E. Susan Amirian, Julie K. Levy   +9 more
doaj   +2 more sources

Cognitive impairment in HTLV-1-associated myelopathy, proviral load and inflammatory markers [PDF]

International Journal of Infectious Diseases, 2019
Objectives: Myelopathy is a well-established long-term clinical manifestation of HTLV-1 infection. Besides motor dysfunction, cognitive impairment may be another consequence of HTLV-1 infection.
Ana Paula Silva Champs, Valéria Maria de Azeredo Passos, Guilherme Carvalho, Sandhi Maria Barreto, Carla Meirelles, Paulo Caramelli   +5 more
doaj   +3 more sources

Development of a predictive model for bovine leukemia virus proviral load. [PDF]

J Vet Intern Med, 2022
Abstract Background There is currently no commercially available method in Canada to identify bovine leukemia virus (BLV)-positive cows with high proviral load (PVL). Objectives First, develop a model to predict PVL ...
John EE, Droscha C, Cameron M, Stryhn H, Keefe G, McClure JT.   +5 more
europepmc   +4 more sources

Evaluation of HTLV-1 activity in HAM/TSP patients using proviral load and Tax mRNA expression after In Vitro lymphocyte activation [PDF]

Iranian Journal of Basic Medical Sciences, 2014
Objective(s):HTLV-1 is the first human retrovirus that has been recognized and is associated with HAM/TSP and ATLL. Studies have shown that less than five percent of HTLV-1 infected carriers develop HAM/TSP or ATLL and about ninety-five percent remain ...
Atefeh Yari, Seyyed Abdolrahim Rezaee, Narges Valizadeh, Taraneh Rajaee, Seyyed Mohammad Jazayeri, Mojdeh Soltani, Mehdi Norouzi   +6 more
doaj   +1 more source

Identification of BoLA Alleles Associated with BLV Proviral Load in US Beef Cows. [PDF]

Pathogens, 2022
Bovine leukemia virus (BLV) causes enzootic bovine leukosis, the most common neoplastic disease in cattle. Previous work estimates that 78% of US beef operations and 38% of US beef cattle are seropositive for BLV. Infection by BLV in a herd is an economic concern for producers as evidence suggests that it causes an increase in cost and a subsequent ...
LaHuis CH, Benitez OJ, Droscha CJ, Singh S, Borgman A, Lohr CE, Bartlett PC, Taxis TM.   +7 more
europepmc   +4 more sources

Longitudinal comparison of HIV‐1 plasma viral load and cellular proviral load [PDF]

Journal of the International AIDS Society, 2014
IntroductionThe goal of antiretroviral treatment (ART) in HIV‐1 infection is the permanent suppression of plasma viral load (pVL) below the currently existing limit of detection of 50 copies/mL (DAIG HIV‐therapy guidelines). Therefore, treatment effectiveness is based on pVL.
Schweitzer, Finja, Mikkola, Visa, Timmen-Wego, Monika, Jensen, Björn, Fätkenheuer, Gerd, Kaiser, Rolf   +5 more
openaire   +2 more sources

Development of a droplet digital PCR assay for quantification of the proviral load of bovine leukemia virus. [PDF]

J Vet Diagn Invest, 2022
Droplet digital PCR (ddPCR) is a highly sensitive tool developed for the detection and quantification of short-sequence variants—a tool that offers unparalleled precision enabling measurement of smaller-fold changes. We describe here the use of ddPCR for the detection of Bovine leukemia virus (BLV) DNA provirus.
De Brun ML, Cosme B, Petersen M, Alvarez I, Folgueras-Flatschart A, Flatschart R, Panei CJ, Puentes R.   +7 more
europepmc   +4 more sources

Point-of-Care System for HTLV-1 Proviral Load Quantification by Digital Mediator Displacement LAMP. [PDF]

Micromachines (Basel), 2021
This paper presents a universal point-of-care system for fully automated quantification of human T-cell lymphotropic virus type 1 (HTLV-1) proviral load, including genomic RNA, based on digital reverse RNA transcription and c-DNA amplification by MD LAMP (mediator displacement loop-mediated isothermal amplification).
Becherer L, Hess JF, Frischmann S, Bakheit M, Nitschko H, Stinco S, Zitz F, Hofer H, Porro G, Hausladen F, Stock K, Drossart D, Wurm H, Kuhn H, Huber D, Hutzenlaub T, Paust N, Keller M, Strohmeier O, Wadle S, Borst N, Zengerle R, von Stetten F.   +22 more
europepmc   +6 more sources

HTLV-1 Proliferation after CD8+ Cell Depletion by Monoclonal Anti-CD8 Antibody Administration in Latently HTLV-1-Infected Cynomolgus Macaques

Microbiology Spectrum, 2023
Human T-cell leukemia virus type 1 (HTLV-1) induces chronic asymptomatic latent infection with a substantial proviral load but without significant viral replication in vivo.
Midori Nakamura-Hoshi, Takushi Nomura, Masako Nishizawa, Trang Thi Thu Hau, Hiroyuki Yamamoto, Midori Okazaki, Hiroshi Ishii, Kenzo Yonemitsu, Yuriko Suzaki, Yasushi Ami, Tetsuro Matano   +10 more
doaj   +1 more source

Bovine leukemia virus proviral load in naturally-infected animals [PDF]

Retrovirology, 2011
Debido a la alta prevalencia del virus de la leucemia bovina (BLV) en los rebaños lecheros argentinos, el control clásico basado en el nivel individual de infección no constituye una estrategia factible. Un enfoque basado en la segregación selectiva de animales según su carga proviral en sangre periférica (PVL) podría ser una alternativa práctica ...
Irene Álvarez, Gerónimo Gutiérrez, Romina Politzki, Cintia Daniela González, Cecilia Martínez, Mariela Gammella, Karina Trono   +6 more
openaire   +1 more source