Results 41 to 50 of about 3,180,845 (188)

High prevalence of skin disorders among HTLV-1 infected individuals independent of clinical status. [PDF]

PLoS Neglected Tropical Diseases, 2013
BackgroundHuman T-cell lymphotropic virus type 1 (HTLV-1) infection can increase the risk of developing skin disorders. This study evaluated the correlation between HTLV-1 proviral load and CD4(+) and CD8(+) T cells count among HTLV-1 infected ...
Renata Okajima, Augusto C P Oliveira, Jerusa Smid, Jorge Casseb, Jose Antonio Sanches   +4 more
doaj   +1 more source

Carga proviral do HTLV-1 e HTLV-2: um método simples através da PCR quantitativa em tempo real HTLV-1 and HTLV-2 proviral load: a simple method using quantitative real-time PCR

Revista da Sociedade Brasileira de Medicina Tropical, 2006
Os vírus linfotrópicos de células T humanas, quando integrados ao genoma da célula hospedeira, provírus, têm como marcador de replicação seu DNA proviral. A carga proviral parece ser um importante fator no desenvolvimento de patologias associadas a estes
Bruna Pedroso Tamegão-Lopes, Priscila Rocha Rezende, Luciana Maria Cunha Maradei-Pereira, José Alexandre Rodrigues de Lemos   +3 more
doaj   +1 more source

Early events following bovine leukaemia virus infection in calves with different alleles of the major histocompatibility complex  DRB3 gene

Veterinary Research, 2020
Cattle maintaining a low proviral load (LPL) status after bovine leukaemia virus (BLV) infection have been recognized as BLV controllers and non-transmitters to uninfected cattle in experimental and natural conditions.
Agustina Forletti, Claudia María Lützelschwab, Rosana Cepeda, Eduardo N. Esteban, Silvina Elena Gutiérrez   +4 more
doaj   +1 more source

TREX1 531C>T Polymorphism is Associated with High Proviral Load Levels in HTLV-1-Infected Persons. [PDF]

Viruses, 2019
Human T-lymphotropic virus type 1 (HTLV-1) deregulates the immune system and cell cycle, resulting in loss of immune tolerance and disease, including HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Silva DC, Amoras EDSG, Moura TCF, Lopes FT, Gomes STM, Costa CAD, Sousa MS, Ishak R, Vallinoto ACR, Queiroz MAF.   +9 more
europepmc   +2 more sources

Influence of INF-gamma gene polymorphism in HTLV-1 proviral load [PDF]

Retrovirology, 2011
Background Interferon-gamma (INF-g) is a key cytokine involved in the defense against intracellular pathogens, such as HTLV-1, by coordinating the expression of immunologically relevant genes. Previous studies showed the importance of this cytokine on HTLV-1-related pathogenesis.
Takayanagui Oswaldo M, Wagatsuma Virgínia M D, Cilião-Alves Daiani C, Rocha–Junior Maurício C, Haddad Rodrigo, Donadi Eduardo A, Covas Dimas T, Kashima Simone   +7 more
openaire   +2 more sources

Quantification of the virus-host interaction in human T lymphotropic virus I infection

Retrovirology, 2005
Background HTLV-I causes the disabling inflammatory disease HAM/TSP: there is no vaccine, no satisfactory treatment and no means of assessing the risk of disease or prognosis in infected people. Like many immunopathological diseases with a viral etiology
Taylor Graham P, Tanaka Yuetsu, Heaps Adrian, Mosley Angelina J, Asquith Becca, McLean Angela R, Bangham Charles RM   +6 more
doaj   +1 more source

Factors Associated with HIV-1 Proviral DNA Loads in Patients with Undetectable Plasma RNA Load

Journal of Korean Medical Science, 2009
To evaluate factors associated with human immunodeficiency virus type 1 (HIV-1) proviral DNA load, we conducted a cross-sectional study of 36 chronically HIV-1-infected individuals with undetectable plasma viral RNA. We used real-time polymerase chain reaction to determine the number of HIV-1 proviral DNA copies per 10(6) peripheral blood mononuclear ...
Choi, Jun Yong, Song, Young Goo, Kim, Young Hwa, Kim, Chang Oh, Kim, Myung Soo, Chin, Bum Sik, Han, Sang Hoon, Choi, Suk Hoon, Lee, Han Sung, Jeong, Su Jin, Choi, Heekyoung, Kim, June Myung   +11 more
openaire   +3 more sources

HIV-1 DNA proviral load in treated and untreated HIV-1 sero-positive patients [PDF]

Clinical Microbiology and Infection, 2010
As proviral human immunodeficiency virus type 1 (HIV-1) DNA can replenish and revive viral infection upon activation, its detection might offer significant therapeutic information, complementing the input provided by plasma RNA determination in the follow-up of infected individuals.
RE, MARIA CARLA, VITONE, FRANCESCA, BIAGETTI, CARLO, SCHIAVONE, PASQUA, Alessandrini F, BON, ISABELLA, DE CRIGNIS, ELISA, GIBELLINI, DAVIDE   +7 more
openaire   +5 more sources

Evaluation of real time PCR technique to diagnosis of human T-lymphotropic virus type I (HTLV-I) in patients in the Hematologia da Fundação Hemope Hospital, in Northeastern Brazil Avaliação da técnica de PCR em tempo real para o diagnóstico do virus linfotrópico tipo I de células T humana (HTLV-I) em pacientes do Hospital de Hematologia da Fundação Hemope, no Nordeste do Brasil

Revista Brasileira de Hematologia e Hemoterapia, 2008
As a high degree of homology exists between the proviral genomes of HTLV-I and HTLV-II, there is significant cross-reactivity. Therefore although detection of HTLV antibodies is characteristic of viral infection, it is not sufficient to confirm the ...
Bruna C. Arruda, Rodrigo A. Lira, Paula Loureiro, Lucas Brandão, Paulo Souza, Wayner V. Souza, Yara M. Gomes   +6 more
doaj   +1 more source

New evidence of bovine leukemia virus circulating in Myanmar cattle through epidemiological and molecular characterization.

PLoS ONE, 2020
Bovine leukemia virus (BLV) is the etiological agent of enzootic bovine leukosis, which is the most common neoplastic disease of cattle. BLV infects cattle worldwide and causes serious problems for the cattle industry.
Kyaw Kyaw Moe, Meripet Polat, Liushiqi Borjigin, Ryosuke Matsuura, Si Thu Hein, Hla Hla Moe, Yoko Aida   +6 more
doaj   +1 more source