Results 61 to 70 of about 3,180,845 (188)

Expression-based analysis of genes related to single nucleotide polymorphism hits associated with bovine leukemia virus proviral load in Argentinean dairy cattle.

Journal of Dairy Science, 2020
In dairy cattle infected with bovine leukemia virus (BLV), the proviral load (PVL) level is directly related to the viral transmission from infected animals to their healthy herdmates.
M. Petersen, H. Carignano, G. S. Archilla, M. E. Caffaro, Irene Alvarez, M. M. Miretti, K. Trono   +6 more
semanticscholar   +1 more source

Effect of bovine leukemia virus infection and proviral load on the systemic profile of dairy heifers during the transition period [PDF]

Ciência Rural
: This study aimed to evaluate the effect of bovine leukemia virus (BLV) on the systemic profile of naturally infected dairy heifers during the transition period. Pregnant Holstein and Jersey heifers (n=24) were distributed in pairs into two experimental
Fabrício Dias Torres, Camila Costa Baccili, Jean Silva Ramos, Larissa Miranda Padilha, Maria Laureana De Brun Méndez, Rodrigo Puentes Palombo, Viviani Gomes   +6 more
doaj   +1 more source

PRMT5 Is Required for Bovine Leukemia Virus Infection In Vivo and Regulates BLV Gene Expression, Syncytium Formation, and Glycosylation In Vitro

Viruses, 2020
Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leukosis, which is the most common neoplastic disease of cattle and is closely related to human T-cell leukemia viruses.
Wlaa Assi, Tomoya Hirose, Satoshi Wada, Ryosuke Matsuura, Shin-nosuke Takeshima, Yoko Aida   +5 more
doaj   +1 more source

Association of Sicca Syndrome with Proviral Load and Proinflammatory Cytokines in HTLV-1 Infection

Journal of Immunology Research, 2016
TheSjögrensyndrome has been diagnosed in patients with HTLV-1 associated myelopathy and dry mouth and dry eyes are documented in HTLV-1 carriers. However the diagnosis ofSjögrensyndrome in these subjects has been contested. In this cross-sectional study, we evaluated the role of immunological factors and proviral load, in sicca syndrome associated with
Clara Mônica Lima, Silvane Santos, Adriana Dourado, Natália B. Carvalho, Valéria Bittencourt, Marcus Miranda Lessa, Isadora Siqueira, Edgar M. Carvalho   +7 more
openaire   +3 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

IFN-γ mRNA expression is lower in Holstein cows infected with bovine leukemia virus with high proviral load and persistent lymphocytosis.

Acta virologica, 2020
Bovine leukemia virus (BLV) is a retrovirus that affects primarily milky cows. Animals serologically positive to BLV show a Th1 cytokine profile with a predominance of gamma interferon (IFN-γ).
C. Úsuga-Monroy, L. G. G. Herrera, J. E. Zuluaga, F. Diaz, A. López-Herrera   +4 more
semanticscholar   +1 more source

Evaluation of the cervicovaginal environment in asymptomatic Human T-cell lymphotropic virus type 1 infected women

Brazilian Journal of Infectious Diseases, 2019
Introduction: Human T-cell lymphotropic virus type 1 (HTLV-1) is sexually transmitted and causes persistent infection. This virus induces activation of the immune system and production of inflammatory cytokines.
Alisson de Aquino Firmino, Adenilda Lima Lopes Martins, Luana Leandro Gois, Taiane Silva Paixão, Everton da Silva Batista, Bernardo Galvão-Castro, Maria Fernanda Rios Grassi   +6 more
doaj   +3 more sources

Determination of proviral load in bovine leukemia virus–infected cattle with and without lymphocytosis

American Journal of Veterinary Research, 2007
Abstract Objective—To determine proviral load in bovine leukemia virus (BLV)–infected cattle with and without persistent lymphocytosis to assess the potential of transmitting the virus. Animals—Cattle in 6 dairy herds. Procedures—Blood samples from infected cows were evaluated 3 times at 6-month intervals for determination of proviral load via PCR ...
Juliarena, Marcela Alicia, Gutiérrez, Silvina Elena, Ceriani, Maria Carolina   +2 more
openaire   +3 more sources

UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation

Advanced Science, EarlyView.
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro, Anna Beekmayer‐Dhillon, Qi Wen Teo, Lewis Siu, Ming Yuan Li, Kate J. Heesom, Adán Pinto‐Fernández, Sumana Sanyal   +7 more
wiley   +1 more source

Controlling bovine leukemia virus in dairy herds by identifying and removing cows with the highest proviral load and lymphocyte counts.

Journal of Dairy Science, 2019
The objective of this field trial was to reduce bovine leukemia virus (BLV) transmission and prevalence in commercial dairy herds using proviral load (PVL) and lymphocyte count (LC) measurements as indicators of the most infectious animals for culling or
Vickie J Ruggiero, B. Norby, O. J. Benitez, H. Hutchinson, K. Sporer, C. Droscha, Cheryl L. Swenson, Paul C. Bartlett   +7 more
semanticscholar   +1 more source