Results 81 to 90 of about 10,657 (203)
Association of the neurologic symptoms with HTLV-1 DNA proviral load.
Association of the neurologic symptoms with HTLV-1 DNA proviral load.
Michel E. Haziot (6654908) +9 more
core +1 more source
IntroductionAlterations in the immune response may influence the development of HTLV-1-associated diseases. TLR3 detects viral nucleic acids, including HTLV-1, and triggers the production of IFN-I and other cytokines. Genetic variations in TLR3 may alter
Fabiane dos Santos Ferreira +18 more
doaj +1 more source
ABSTRACT Introduction The elimination of vertical transmission of HIV is a global health priority endorsed by the Pan American Health Organization (PAHO) and the World Health Organization (WHO), aligned with the Sustainable Development Goals (SDGs). Brazil has made substantial progress towards this goal through sustained investment in universal health ...
Pâmela Cristina Gaspar +58 more
wiley +1 more source
T-cell subsets and proviral load in AC, HAM and ATL.
T-cell subsets and proviral load in AC, HAM and ATL.
Graham P. Taylor (42474) +3 more
core +1 more source
Human Gut Phageome Analysis Uncovers Thousands of Highly Modular Endolysins
Analysis of 9141 human gut metagenomes identified 15,267 phage genomes and 3794 highly modular endolysins. The recovered endolysins showed remarkable catalytic and cell wall–binding domain diversity, highlighting the gut phageome as a rich source of novel enzybiotics with therapeutic potential against multidrug‐resistant bacteria.
Raphael Kabir Niloy +6 more
wiley +1 more source
Metabolic Regulation of Immune Responses: Molecular Mechanisms, Diseases, and Therapeutic Targets
FBP1 loss drives immune evasion and therapy resistance by enhancing glycolysis, STAT3 activation, and PD‐L1 expression, leading to T cell exhaustion and NK cell inhibition. FBP1 restoration, via LNP‐mRNA or epigenetic modulation, reverses these immunosuppressive effects, reactivates cytotoxic T cells, promotes M1 macrophage polarization, and enhances ...
Chunwei Li +10 more
wiley +1 more source
Ratio of TNF-α/IL-10 (A) and IL-12/IL-10 (B) of patients with high and medium proviral load (gray rectangles) as compared to patients with low proviral load (white rectangles).
Ana Carolina Campi-Azevedo (294819) +13 more
core +1 more source
Virological and Immunological Aspects of AIDS Pathogenesis
The most common and serious problem associated with long term antiretroviral therapy is waning efficacy over time. To date. a number of studies has suggested an association between drug resistance and clinical deterioration. However.
Brian Conway, Francisco J Diaz-Mitoma
doaj +1 more source
Hazard ratios for all-cause and cause-specific mortality according to HTLV-1 proviral load status.
Hazard ratios for all-cause and cause-specific mortality according to HTLV-1 proviral load status.
Charles Bangham (3429920) +7 more
core +1 more source
T‐Cell Biology in the Female Reproductive Tract: Relevance to HIV Infection
ABSTRACT Worldwide, most HIV infections occur across a mucosal surface during sexual contact, with women accounting for nearly half of reported new HIV infections across the globe in 2024. Most new infections in women and girls are believed to involve transmission across mucosal surfaces of the lower reproductive tract, which includes the vagina and ...
Barbara L. Shacklett +2 more
wiley +1 more source

