Host genetic factors associated to proviral load in Peruvian HTLV-1 infected [PDF]
Patients with HTLV-1 associated myelopathy (HAM/TSP) tend to present higher HTLV-1 proviral load (PVL) than asymptomatic carriers (AC). PVL remains the only marker consistently associated with HAM/TSP across several populations. We report a candidate gene study to identify associations between host genetic markers and PVL.
Clark Daniel +10 more
openaire +2 more sources
Unfolding Plant Defence: Endoplasmic Reticulum Stress Signalling at the Plant‐Pathogen Interface
ABSTRACT The endoplasmic reticulum (ER) stress response, a conserved proteostasis network, has emerged as a central hub that reprograms plant immunity during pathogen attack. This review synthesises how plants harness ER‐stress signalling to mount multilayered defences and how pathogens have evolved counterstrategies to subvert these pathways.
Zhe Meng +8 more
wiley +1 more source
APH-2 and Tax expression are correlated with a HTLV-2 proviral load but not with lymphocytosis [PDF]
The recent discovery of HBZ, an antisense protein, encoded by HTLV-1 allowed a new way of understanding how HTLV-1 induces the development of adult T cell leukemia/lymphoma (ATLL). HBZ mRNA is expressed in all HTLV-1 patients tested regardless of their clinical status.
Douceron, Estelle +5 more
openaire +2 more sources
Clonal Expansion of Human T-Cell Leukemia Virus Type II in Patients with High Proviral Load
In previous studies we demonstrated that individuals infected by human T-cell leukemia virus type II (HTLV-II) presented a high degree of variation in proviral load and that the cellular tropism of this virus was expanded in some patients to B ...
Gessain, Antoine +4 more
core +1 more source
Pregnancy does not adversely impact diagnostic tests for HTLV-1/2 infection. [PDF]
Mother-to-child-transmission (MTCT) of human T-cell lymphotropic virus type-1(HTLV-1) contributes disproportionately to the burden of HTLV-1 associated diseases.
Carolina Rosadas +3 more
doaj +1 more source
Cucumber green mottle mosaic virus: A persistent seed‐borne threat to cucurbits
Cucumber green mottle mosaic virus (CGMMV) is a highly stable, seed‐borne tobamovirus that threatens global cucurbit production. Its efficient mechanical and seed transmission, long‐term environmental persistence, and the spread of Clade II CGMMV isolates drive its rapid dissemination and cause severe yield losses.
Esperanza Gea‐Caballero +1 more
wiley +1 more source
NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang +10 more
wiley +1 more source
Proviral load of asymptomatic HTLV-1 carries from the North region vs Center region.
Proviral load of asymptomatic HTLV-1 carries from the North region vs Center region.
Ariel Fridman (7961834) +11 more
core +1 more source
ABSTRACT Bovine leukemia virus (BLV), an oncogenic deltaretrovirus, establishes lifelong infection in cattle and induces enzootic bovine leukosis in a subset of animals following prolonged latency. Despite extensive evidence of immune dysregulation, stage‐specific transcriptional reprogramming of B cells, the primary viral reservoir remains ...
Mohammad Mehdi Akbarin +6 more
wiley +1 more source
A novel association of BoLA DRB3 alleles in BLV infected cattle with different proviral loads
O vírus da leucemia bovina (BLV) está associado à doença neoplásica mais comum do gado bovino. O BLV tem uma disseminação silenciosa no rebanho devido à troca de células infectadas, assim, a concentração de células BLV infectadas no sangue deve desempenhar um papel importante no sucesso da transmissão viral.
Nieto Farías, María Victoria +6 more
openaire +4 more sources

