Results 1 to 10 of about 107,551,550 (224)

The challenge of HTLV-1 therapeutics: lessons from anti-protease approaches [PDF]

New Microbes and New Infections
The human T-cell leukaemia virus type 1 (HTLV-1) is an oncogenic retrovirus responsible for severe diseases, including adult T-cell leukaemia/lymphoma (ATLL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Despite its significant
Sanaz Ahmadi Ghezeldasht, Raheleh Miri, Seyed Khosrow Shamsian, Arman Mosavat, Seyed Abdolrahim Rezaee   +4 more
doaj   +2 more sources

Human T Lymphotropic Virus Type 1 (HTLV-1): Molecular Biology and Oncogenesis

Viruses, 2010
Human T lymphotropic viruses (HTLVs) are complex deltaretroviruses that do not contain a proto-oncogene in their genome, yet are capable of transforming primary T lymphocytes both in vitro and in vivo.
Patrick L Green
exaly   +3 more sources

FC-duplex IgG1 (HTLV-1/2): Qualifying the flow cytometry IgG1 duplex assay for differential diagnosis of HTLV-1 and HTLV-2 infections. [PDF]

PLoS Neglected Tropical Diseases
Human T-lymphotropic virus (HTLV) infection has been implicated in a broad spectrum of clinical conditions, encompassing both neoplastic and inflammatory-degenerative disorders, associated with relevant immunological dysfunctions.
Júlia Pereira Martins, Felipe Araujo Santos, Kelly Alves Bicalho, Jordana Grazziela Alves Coelho-Dos-Reis, Vanessa Peruhype-Magalhães, Maísa Aparecida Ribeiro, Renata Glória Sá, Lucas Pedreira de Carvalho, Antonio Carlos Rosário Vallinoto, Laurence Rodrigues Amaral, Anna Barbara de Freitas Carneiro-Proietti, Andréa Teixeira-Carvalho, Allyson Guimarães Costa, Olindo Assis Martins-Filho, Márcio Sobreira Silva Araújo   +14 more
doaj   +2 more sources

PREVALENCE OF HIV-1/HTLV-1 CO-INFECTION AND BEHAVIORAL RISK AMONG PEOPLE LIVING WITH HIV IN BELO HORIZONTE, BRAZIL

Revista de Salud Pública, 2023
Objective: To analyze the prevalence of HIV-1 and HTLV-1 co-infection and risk behavioral for sexually transmitted infections (STIs) and the quality of life among people living with HIV-1 (PL-HIV-1).
Poliane Cristina Vertêlo, Alexandre Braga Miranda, Ludimila Labanca, Ana Lúcia Borges-Starling, Cláudio Daniel Cerdeira, Carlos Felipe Nogueira, Denise Utsch Gonçalves   +6 more
doaj   +1 more source

بررسی پروفایل لیپیدی و بیان ژن Tax در بیماران قلبی آلوده به HTLV-1 [PDF]

Majallah-i Dānishkadah-i Pizishkī-i Dānishgāh-i ̒ Ulūm-i Pizishkī-i Mashhad., 2019
مقدمه آترواسکلروزیس یکی از عوامل شایع مرگ و میر در کشورهای پیشرفته و در حال توسعه بوده و التهاب مزمن از عوامل خطر در بیماری آترواسکلروزیس می‎باشد. هدف از پژوهش حاضر، بررسی تاثیر آلودگی به HTLV-1 بر حضور یا عدم حضور و وسعت بیماری آترواسکلروزیس در منطقه ...
فاطمه سادات محمدی, محمود محمدزاده شبستری, آرمان مساوات, فائزه ثابت, فرناز مزینی, فرحزاد جباری آزاد, عبدالرحیم رضایی   +6 more
doaj   +1 more source

HTLV-1/2 Infection in Blood Donors from a Non-Endemic Area (Catalonia, Spain) between 2008 and 2017: A 10-Year Experience

Viruses, 2022
Human T-cell lymphotropic virus type 1 and 2 (HTLV-1/2) screening is not mandatory in Spanish blood banks. In Catalonia, selective screening was introduced in 2008, followed by universal screening in 2011.
Maria Piron, Fernando Salvador, Estrella Caballero, Adrián Sánchez-Montalvá, Marta Bes, Natàlia Casamitjana, Lluís Puig, Israel Molina, Silvia Sauleda   +8 more
doaj   +1 more source

High prevalence of skin disorders among HTLV-1 infected individuals independent of clinical status. [PDF]

PLoS Neglected Tropical Diseases, 2013
BackgroundHuman T-cell lymphotropic virus type 1 (HTLV-1) infection can increase the risk of developing skin disorders. This study evaluated the correlation between HTLV-1 proviral load and CD4(+) and CD8(+) T cells count among HTLV-1 infected ...
Renata Okajima, Augusto C P Oliveira, Jerusa Smid, Jorge Casseb, Jose Antonio Sanches   +4 more
doaj   +1 more source

Spread of Human T-Lymphotropic Virus 1 and 2 Among Relatives of People Who Use Illicit Drugs in Northern Brazil

Frontiers in Microbiology, 2022
The human T-lymphotropic virus 1 (HTLV-1) and 2 (HTLV-2) can be transmitted between humans by mechanisms associated with horizontal and vertical routes.
Aldemir Branco Oliveira-Filho, Aldemir Branco Oliveira-Filho, Paula Cristina Rodrigues Frade, Ricardo Roberto de Souza Fonseca, Leila Sawada, Luísa Caricio Martins, Luísa Caricio Martins, Luiz Fernando Almeida Machado, Luiz Fernando Almeida Machado, Antonio Carlos Rosário Vallinoto, Antonio Carlos Rosário Vallinoto, Ricardo Ishak, Ricardo Ishak, José Alexandre Rodrigues de Lemos, Benedikt Fischer, Benedikt Fischer, Emil Kupek   +16 more
doaj   +1 more source

Multi-Epitope Protein as a Tool of Serological Diagnostic Development for HTLV-1 and HTLV-2 Infections

Frontiers in Public Health, 2022
A multi-epitope protein expressed in a prokaryotic system, including epitopes of Env, Gag, and Tax proteins of both HTLV-1 and HTLV-2 was characterized for HTLV-1/2 serological screening.
Gabriela de Melo Franco, Gabriela de Melo Franco, Anderson Santos da Rocha, Anderson Santos da Rocha, Laura Jorge Cox, Laura Jorge Cox, Danielle Soares de Oliveira Daian e Silva, Danielle Soares de Oliveira Daian e Silva, Débora Marques da Silveira e Santos, Débora Marques da Silveira e Santos, Marina Lobato Martins, Marina Lobato Martins, Luis Claudio Romanelli, Luis Claudio Romanelli, Ricardo Ishak, Antonio C. R. Vallinoto, Maria Rosa Q. Bomfim, Adele Caterino-de-Araujo, Jordana G. A. Coelho-dos-Reis, Jordana G. A. Coelho-dos-Reis, Flávio Guimarães da Fonseca, Edel Figueiredo Barbosa-Stancioli, Edel Figueiredo Barbosa-Stancioli   +22 more
doaj   +1 more source

Provirus Mutations of Human T-Lymphotropic Virus 1 and 2 (HTLV-1 and HTLV-2) in HIV-1-Coinfected Individuals

mSphere, 2020
Provirus mutations of human T-lymphotropic virus 1 (HTLV-1), mostly the lack of the 5′ long terminal repeat (LTR) genomic region, have been described and associated with severe adult T cell leukemia/lymphoma (ATLL), non-sense point mutations with low ...
Karoline Rodrigues Campos, Adele Caterino-de-Araujo   +1 more
doaj   +1 more source