Results 41 to 50 of about 29,732,513 (224)

HTLV-1 and Innate Immunity [PDF]

Viruses, 2011
Innate immunity plays a critical role in the host response to a viral infection. The innate response has two main functions. First, it triggers effector mechanisms that restrict the infection. Second, it primes development of the adaptive response, which completes the elimination of the pathogen or of infected cells.
Journo, Chloé, Mahieux, Renaud
openaire   +3 more sources

Cellular factors involved in HTLV-1 entry and pathogenicity

Frontiers in Microbiology, 2012
Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of adult T cell leukemia (ATL) and HTLV-1–associated myelopathy and tropical spastic paraparesis (HAM/TSP).
Hiroo eHoshino
doaj   +1 more source

Development of a Monoclonal Antibody Targeting HTLV-1 Envelope gp46 Glycoprotein and Its Application to Near-Infrared Photoimmuno-Antimicrobial Strategy

Viruses, 2022
Human T-cell leukemia virus type 1 (HTLV-1), a retrovirus, causes adult T-cell leukemia-lymphoma, HTLV-1 associated myelopathy/tropical spastic paraparesis, and HTLV-1 uveitis.
Yasuyoshi Hatayama, Yutaro Yamaoka, Takeshi Morita, Sundararaj Stanleyraj Jeremiah, Kei Miyakawa, Mayuko Nishi, Yayoi Kimura, Makoto Mitsunaga, Tadayuki Iwase, Hirokazu Kimura, Naoki Yamamoto, Akifumi Takaori-Kondo, Hideki Hasegawa, Akihide Ryo   +13 more
doaj   +1 more source

Comparative studies between HTLV-1 and HTLV-2 function and pathobiology

, 2015
Human T-cell leukemia viruses type 1 and 2 (HTLV-1 and HTLV-2) share a common genetic organization, expression strategy and ability to infect and immortalize T-cells in vitro; however, HTLV-1 and HTLV-2 are strikingly different in terms of clinical ...
Francoise Bex, Umberto Bertazzoni, Bertazzoni, Umberto, Bex, Françoise   +3 more
core   +1 more source

日本に分布するHTLV-1株からみた生物系統地理学 [PDF]

, 2016
We conducted phylogenetic analyses and an estimation of coalescence times for East Asian strains of HTLV-1. Phylogenetic analyses showed that the following three lineages exist in Japan: “JPN”, primarily comprising Japanese isolates; “EAS”, comprising ...
大谷, 正史
core   +1 more source

Synergistic effects of HDAC inhibitor tucidinostat and ENT inhibitor dipyridamole in T-cell malignancies

Scientific Reports
Achieving both selectivity and cytotoxicity against cancer cells remains a major challenge in cancer therapy. Histone deacetylase (HDAC) inhibitors, such as tucidinostat, suppress tumor growth by epigenetically regulating tumor suppressor gene expression
Jiazhou Li, Ahmed E. Goda, Daniel Enriquez-Vera, Shuhei Fujii, Satomi Harazono, Jhajaira M. Araujo, Nao Nishikoba, Sophia Velarde, Atakan Zeki Namli, Alvaro De Jesus Huamani Ortiz, Shingo Nakahata   +10 more
doaj   +1 more source

HAS-Flow May Be an Adequate Method for Evaluating Human T-Cell Leukemia Virus Type 1 Infected Cells in Human T-Cell Leukemia Virus Type 1-Positive Rheumatoid Arthritis Patients Receiving Antirheumatic Therapies: A Retrospective Cross-Sectional Observation Study

Viruses, 2023
The study aims to assess the usefulness of human T-cell leukemia virus type 1 (HTLV-1)-infected cell analysis using flow cytometry (HAS-Flow) as a monitoring method for adult T-cell leukemia (ATL) development in HTLV-1-positive patients with rheumatoid ...
Kunihiko Umekita, Yuki Hashikura, Akira Takaki, Masatoshi Kimura, Katsumi Kawano, Chihiro Iwao, Shunichi Miyauchi, Takeshi Kawaguchi, Motohiro Matsuda, Yayoi Hashiba, Toshihiko Hidaka   +10 more
doaj   +1 more source

HTLV-1 Tax mutants that do not induce Garrest are disabled in activating the anaphase promoting complex-1

, 2011
Copyright information:Taken from "HTLV-1 Tax mutants that do not induce Garrest are disabled in activating the anaphase promoting complex"http://www.retrovirology.com/content/4/1/35Retrovirology 2007;4():35-35.Published online 29 May 2007PMCID:PMC1894815.
Randall Merling (75706), Chou-Zen Giam (75711), Sohee Hong (75708), Meihong Liu (75709), Yu-Liang Kuo (75710), Ling Zhang (18071), Chunhua Chen (75707)   +6 more
core   +1 more source

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

Biological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad, Suresha G. Prabhu, Lizna M. Ali, Vineeta N. Pillai, Farah Mustafa, Tahir A. Rizvi   +5 more
wiley   +1 more source

Заболевания, ассоциированные с Т-лимфотропным вирусом типа 1 человека (HTLV-1)

Microbiology Independent Research Journal
ВВЕДЕНИЕ: Т-лимфотропный вирус типа 1 человека (HTLV-1) относится к семейству Retroviridae (род Deltaretrovirus ) и напрямую участвует в канцерогенезе.
Л. В. Радыгина, Л. В. Мочалова   +1 more
doaj   +1 more source