Results 51 to 60 of about 21,273,309 (234)
HTLV-1 reads aligned to HTLV-1 sequences of the NCBI sequence data base.
, 2019 HTLV-1 reads aligned to HTLV-1 sequences of the NCBI sequence data base.
Claudia Pommerenke (150761) +3 more
core +1 more source
Screening transplant donors for HTLV-1 and -2
, 2016 Human T-cell leukemia virus-1 (HTLV-1) is the first pathogenic human retrovirus discovered in 1980.1 HTLV-1 causes 2 devastating diseases: adult T-cell leukemia/lymphoma (ATL) and a neurological disorder, HTLV-1–associated myelopathy/tropical spastic ...
Willems, Luc +3 more
core +1 more source
The HTLV-1 Virological Synapse [PDF]
Viruses, 2010 Human T-lymphotropic virus-1 (HTLV-1) spreads efficiently between T-cells via a tight and highly organized cell-cell contact known as the virological synapse. It is now thought that many retroviruses and other viruses spread via a virological synapse, which may be defined as a virus-induced, specialized area of cell-to-cell contact that promotes the ...
Mohamed Nejmeddine, Charles R.M. Bangham
openaire +3 more sources
Comparative studies between HTLV-1 and HTLV-2 function and pathobiology
, 2015 Human T-cell leukemia viruses type 1 and 2 (HTLV-1 and HTLV-2) share a common genetic organization, expression strategy and ability to infect and immortalize T-cells in vitro; however, HTLV-1 and HTLV-2 are strikingly different in terms of clinical ...
Francoise Bex +3 more
core +1 more source
Scientific ReportsAchieving both selectivity and cytotoxicity against cancer cells remains a major challenge in cancer therapy. Histone deacetylase (HDAC) inhibitors, such as tucidinostat, suppress tumor growth by epigenetically regulating tumor suppressor gene expression
Jiazhou Li +10 more
doaj +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
, 2011 Copyright information:Taken from "HTLV-1 Tax mutants that do not induce Garrest are disabled in activating the anaphase promoting complex"http://www.retrovirology.com/content/4/1/35Retrovirology 2007;4():35-35.Published online 29 May 2007PMCID:PMC1894815.
Randall Merling (75706) +6 more
core +1 more source
Заболевания, ассоциированные с Т-лимфотропным вирусом типа 1 человека (HTLV-1)
Microbiology Independent Research JournalВВЕДЕНИЕ: Т-лимфотропный вирус типа 1 человека (HTLV-1) относится к семейству Retroviridae (род Deltaretrovirus ) и напрямую участвует в канцерогенезе.
Л. В. Радыгина +1 more
doaj +1 more source
The Exceptional Oncogenicity of HTLV-1 [PDF]
Frontiers in Microbiology, 2017 Human T-cell leukemia virus-1 (HTLV-1) is the first pathogenic human retrovirus identified in 1979 by the Gallo group. HTLV-1 causes fatal T-cell leukemia (adult T cell leukemia) and a progressive myelopahy (HTLV-1-associated myelopathy/ tropical spastic paraparesis, HAM/TSP) and other disorders.
Tagaya, Yutaka, Gallo, Robert C.
openaire +3 more sources
Humanized immune system animal models and their recent applications
Animal Models and Experimental Medicine, EarlyView.In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli +6 more
wiley +1 more source