Results 51 to 60 of about 107,551,550 (224)

HTLV-1 infection and health outcomes

, 2020
The meta-analysis published by Gill Schierhout and colleagues1 reported an increased relative risk of premature death in individuals infected with HTLV-1 compared with individuals not infected with HTLV-1 (RR 1·57, 95% CI 1·37–1·80).
Mendoza, Carmen de, Ramos, José M., Soriano, Vicente, Soriano, Vicente (1)   +3 more
core   +1 more source

Epidemiological analysis of HTLV-1 and HTLV-2 infection among different population in Central China. [PDF]

PLoS ONE, 2013
BACKGROUND: HTLV-1 and HTLV-2 are retroviruses linked etiologically to various human diseases, and both of them can be transmitted by vertical route, sexual intercourse, blood transfusion and intravenous drug use.
Yunyun Ma, Shangen Zheng, Na Wang, Yu Duan, Xinyu Sun, Jing Jin, Wenqiao Zang, Min Li, Yuanyuan Wang, Guoqiang Zhao   +9 more
doaj   +1 more source

Rapid and Efficient Affinity Isolation of Engineered Extracellular Vesicles Encapsulating Functional Proteins via Internal Twin‐Strep Tetraspanin Tagging

Small, EarlyView.
Structure‐guided internal twin‐Strep tagging of the tetraspanins CD63 or CD9 enables rapid and efficient antibody‐free affinity isolation of engineered extracellular vesicles (EVs) using Strep technology while allowing luminal protein loading. The approach removes over 96% of contaminants, separates tagged EVs from coexisting viral particles, and ...
Minh‐Tu Pham, Jona Benjamin Krohn, Janis Meyer, Christian Ritter, Martin Schneider, Dominic Helm, Dario Frey, Kleopatra Rapti, Uta Haselmann‐Weiss, Elif Toprak, Viet Loan Dao Thi, Florian Leuschner, Dirk Grimm, Karl Rohr, Ralf Bartenschlager   +14 more
wiley   +1 more source

Updates on HTLV-1 Uveitis

Viruses, 2022
HTLV-1 uveitis (HU) is the third clinical entity to be designated as an HTLV-1-associated disease. Although HU is considered to be the second-most frequent HTLV-1-associated disease in Japan, information on HU is limited compared to that on adult T-cell leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy (HAM).
Koju Kamoi, Toshiki Watanabe, Kaoru Uchimaru, Akihiko Okayama, Seiko Kato, Toyotaka Kawamata, Hisako Kurozumi-Karube, Noe Horiguchi, Yuan Zong, Yoshihisa Yamano, Isao Hamaguchi, Yasuhito Nannya, Arinobu Tojo, Kyoko Ohno-Matsui   +13 more
openaire   +3 more sources

HTLV-1/2 proviral load by sex and age among rural population in Gabon, central Africa.

, 2018
Rectangle: Average magnitude of HTLV1/2 proviral load; Line: Median proviral load; Bar: Standard deviation. HTLV-1/2 proviral load was measured by a multiplex real-time PCR assay involving a molecular beacon probe for simultaneous detection ...
Maria Makuwa (131491), Guillaume Besson (313049), Melanie Caron (2558596), Eric Leroy (264004), Dieudonne Nkoghe (3404600), Cindy Padilla (201518), Mirdad Kazanji (136517)   +6 more
core   +1 more source

Analysis of temporal expression of HTLV-2 reveals similarities and functional differences from HTLV-1 [PDF]

, 2011
In the present study, we developed a robust splice site-specific real-time RT-PCR method to quantitate all HTLV-2 transcripts. Results of this analysis conducted on three different infected cell lines (HTLV-2A Mo-T , C344 and HTLV-2B BJAB-Gu) showed that
Bender Cecilia, Rende Francesca, Cavallari Ilaria, C. Casoli, Alessia Cotena, I. Cavallari, A. Cotena, Cecilia Bender, Ciminale Vincenzo, Casoli Claudio, P. Ronzi, C. Bender, U. Bertazzoni, Umberto Bertazzoni, Paola Ronzi, Francesca Rende, Ilaria Cavallari, Bertazzoni Umberto, V. Ciminale, Vincenzo Ciminale, F. Rende, Ronzi Paola, Cotena Alessia, Claudio Casoli   +23 more
core   +1 more source

Tocilizumab has no direct effect on cell lines infected with human T-cell leukemia virus type 1

Journal of International Medical Research, 2021
Objective It remains unclear whether human T-cell leukemia virus type 1 (HTLV-1) infection influences therapeutic responses in patients with rheumatic diseases and whether immunosuppressive treatments increase the risk of HTLV-1-related complications in ...
Yushiro Endo, Shoichi Fukui, Tomohiro Koga, Daisuke Sasaki, Hiroo Hasegawa, Katsunori Yanagihara, Akihiko Okayama, Tatsufumi Nakamura, Atsushi Kawakami, Hideki Nakamura   +9 more
doaj   +1 more source

Flow cytometric assessment of T‐cell receptor β‐chain constant region 1/2 skewing as a surrogate marker for clonality in human T‐cell leukaemia virus type‐1–infected cells

British Journal of Haematology, EarlyView.
Summary Estimating T‐cell clonality within human T‐cell leukaemia virus type 1 (HTLV‐1)–infected cell populations may aid risk assessment and diagnosis of adult T‐cell leukaemia/lymphoma (ATL). However, direct assessment of HTLV‐1 integration‐site clonality requires genetic analyses that are costly and labour‐intensive.
Koji Jimbo, Aileen G. Rowan, Momoko Usui, Kako Suzuki, Makoto Yamagishi, Junya Makiyama, Lucy B. M. Cook, Yoshihisa Yamano, Kaoru Uchimaru, Yasuhito Nannya, Shigeo Fuji   +10 more
wiley   +1 more source

Distinct Clinical Features of Multiple Myeloma With t(11;14): A Post Hoc Analysis of JSH‐MM‐15 Study

Cancer Science, EarlyView.
t(11;14)‐positive MM is a clinically distinct subgroup characterized by intermediate prognostic risk, modest response depth, and treatment‐dependent outcomes. ABSTRACT t(11;14) (q13;q32) occurs in approximately 15%–25% of multiple myeloma (MM) cases and has traditionally been regarded as a standard cytogenetic risk factor.
Taku Tsukamoto, Yuji Shimura, Shinsuke Mizutani, Takahiro Fujino, Haruya Okamoto, Mitsuhiro Itagaki, Hiroshi Handa, Takayuki Shimizu, Morio Sawamura, Tadao Ishida, Satoru Kosugi, Shuichi Ota, Makoto Yoshimitsu, Yutaka Shimazu, Isamu Sugiura, Hirohiko Shibayama, Shin‐ichi Fuchida, Hiroyuki Takamatsu, Akiko M. Saito, Hitoshi Kiyoi, Koichi Akashi, Itaru Matsumura, Akifumi Takaori‐Kondo, Junya Kuroda, Shinsuke Iida   +24 more
wiley   +1 more source

The Exceptional Oncogenicity of HTLV-1 [PDF]

Frontiers in Microbiology, 2017
Human T-cell leukemia virus-1 (HTLV-1) is the first pathogenic human retrovirus identified in 1979 by the Gallo group. HTLV-1 causes fatal T-cell leukemia (adult T cell leukemia) and a progressive myelopahy (HTLV-1-associated myelopathy/ tropical spastic paraparesis, HAM/TSP) and other disorders.
Tagaya, Yutaka, Gallo, Robert C.
openaire   +3 more sources