Results 61 to 70 of about 29,732,513 (224)

The Exceptional Oncogenicity of HTLV-1 [PDF]

Frontiers in Microbiology, 2017
Human T-cell leukemia virus-1 (HTLV-1) is the first pathogenic human retrovirus identified in 1979 by the Gallo group. HTLV-1 causes fatal T-cell leukemia (adult T cell leukemia) and a progressive myelopahy (HTLV-1-associated myelopathy/ tropical spastic paraparesis, HAM/TSP) and other disorders.
Tagaya, Yutaka, Gallo, Robert C.
openaire   +3 more sources

Reflections on Some of the Exceptional Features of HTLV-1 and HTLV-1 Research: A Perspective

Frontiers in Immunology, 2022
The report is not a review or a summary. In a manner, it is a perspective but an unusual one. It looks back to the years my colleagues and I (RG) began preparing for human retroviruses (beginning in 1970), how they evolved, and attempts to bring to light or simply to emphasize many exceptional characteristics of a retrovirus known as HTLV-1 and some ...
Gallo, Robert C., Tagaya, Yutaka
openaire   +3 more sources

HTLV screening and confirmatory testing among blood donors in São Paulo: A cross‐sectional study

Transfusion Medicine, EarlyView.
Abstract Introduction Human T‐cell lymphotropic virus types 1 and 2 (HTLV‐1/2) are transfusion‐transmissible retroviruses associated with severe diseases, and blood donor screening is mandatory in Brazil. Increasing HTLV‐related discard rates at our institution prompted this study to determine the prevalence and incidence of HTLV‐1/2 and to investigate
Suzete C. Ferreira, Anna S. Nishyia, Jerenice E. Ferreira, Claudia Di Lorenzo Oliveira, Cesar de Almeida‐Neto, Tila Fanciani, Katia C. Dantas, Juliana Derriga, Silvia Petrossi Gallo Polato, Nanci Salles, Vanderson Rocha, Alfredo Mendrone‐Junior   +11 more
wiley   +1 more source

Hepatitis C viral load in HCV-monoinfected and HCV/HIV-1-, HCV/HTLV-1/-2-, and HCV/HIV/HTLV-1/-2-co-infected patients from São Paulo, Brazil

Brazilian Journal of Infectious Diseases, 2018
Co-infections of hepatitis C virus (HCV) and either human immunodeficiency virus type 1 (HIV-1), human T-cell lymphotropic virus type 1 (HTLV-1) or type 2 (HTLV-2) have been described as having an impact on HCV viremia and subsequent disease progression.
Fabiana Aparecida Alves, Karoline Rodrigues Campos, Marcílio Figueiredo Lemos, Regina Célia Moreira, Adele Caterino-de-Araujo   +4 more
doaj   +1 more source

HTLV-1 pathogenesis mediated by HTLV-1 bZIP factor

Uirusu, 2012
HTLV-1 is a retrovirus associated with human diseases, such as ATL or HAM/TSP. More than thirty years have passed since HTLV-1 was discovered, but the precise mechanism of HTLV-1 pathogenesis still remains elusive. HTLV-1 bZIP factor (HBZ) was reported ten years ago as a viral gene encoded in the minus strand of HTLV-1.
openaire   +3 more sources

Analysis of temporal expression of HTLV-2 reveals similarities and functional differences from HTLV-1 [PDF]

, 2011
In the present study, we developed a robust splice site-specific real-time RT-PCR method to quantitate all HTLV-2 transcripts. Results of this analysis conducted on three different infected cell lines (HTLV-2A Mo-T , C344 and HTLV-2B BJAB-Gu) showed that
Bender Cecilia, Rende Francesca, Cavallari Ilaria, C. Casoli, Alessia Cotena, I. Cavallari, A. Cotena, Cecilia Bender, Ciminale Vincenzo, Casoli Claudio, P. Ronzi, C. Bender, U. Bertazzoni, Umberto Bertazzoni, Paola Ronzi, Francesca Rende, Ilaria Cavallari, Bertazzoni Umberto, V. Ciminale, Vincenzo Ciminale, F. Rende, Ronzi Paola, Cotena Alessia, Claudio Casoli   +23 more
core   +1 more source

Ovarian hormone loss modifies the nucleic acid cargo of circulating extracellular vesicles and skeletal muscle metabolism after acute exercise in rats

Experimental Physiology, EarlyView.
Abstract Loss of ovarian hormones (i.e., menopause) leads to negative effects on metabolic health. While exercise offers significant benefits, it seems to be insufficient to completely reverse these changes. The mechanisms by which exercise conveys the effects throughout the body are still poorly understood.
Veera Puumalainen, Anni Maja, Tia‐Marje Korhonen, Tuuli A. Nissinen, Eero Hulkko, Janne A. Ihalainen, Maarit Lehti, Sira Karvinen   +7 more
wiley   +1 more source

The HTLV-1 Tax interactome [PDF]

Retrovirology, 2008
Abstract The Tax1 oncoprotein encoded by Human T-lymphotropic virus type I is a major determinant of viral persistence and pathogenesis. Tax1 affects a wide variety of cellular signalling pathways leading to transcriptional activation, proliferation and ultimately transformation. To carry out these functions, Tax1 interacts with and modulates
Boxus, Mathieu, Twizere, Jean-Claude, Legros, Sebastien, Dewulf, Jean-François, Kettmann, Richard, Willems, Luc   +5 more
openaire   +4 more sources

HIV Testing and Care Among Publicly Insured Enrollees With Schizophrenia: Is There a Benefit to Dual Eligibility?

Psychiatric Research and Clinical Practice, EarlyView.
Background Patients with schizophrenia experience gaps in the human immunodeficiency virus (HIV) care continuum. We examined the impact of dual enrollment in Medicare upon HIV testing and retention among Medicaid‐enrolled patients with schizophrenia.
Karly Murphy, Marilyn D. Thomas, Paola Alonso‐Fraire, Alexander R. Bazazi, Priya Dahiya, Mark Olfson, Francine Cournos, Emily Arnold, James Dilley, Paul Wesson, Richard Hermida, James Walkup, Stephen Crystal, Christina Mangurian   +13 more
wiley   +1 more source

HTLV-1/2 proviral load by sex and age among rural population in Gabon, central Africa.

, 2018
Rectangle: Average magnitude of HTLV1/2 proviral load; Line: Median proviral load; Bar: Standard deviation. HTLV-1/2 proviral load was measured by a multiplex real-time PCR assay involving a molecular beacon probe for simultaneous detection ...
Maria Makuwa (131491), Guillaume Besson (313049), Melanie Caron (2558596), Eric Leroy (264004), Dieudonne Nkoghe (3404600), Cindy Padilla (201518), Mirdad Kazanji (136517)   +6 more
core   +1 more source