Results 71 to 80 of about 21,273,309 (234)

Experiencing 50 Years of Synergistic Development in Structural Biology and Enzymology

Journal of the Chinese Chemical Society, EarlyView.
Picture of Sunney Chan with Academia Sinica (AS) President James C. Liao and three Vice Presidents: Shin‐Kun Peng (left one), Tang K. Tang (right one), and Mei‐Yin Chou (right 2), taken at the annual Chinese New Year's Banquet of AS, February 7, 2025. This was likely Sunney's last appearance in formal activities of AS.
Ming‐Daw Tsai
wiley   +1 more source

No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasms

, 2007
Background The Deltaretrovirus genus comprises viruses that infect humans (HTLV), various simian species (STLV) and cattle (BLV). HTLV-I is the main causative agent in adult T-cell leukemia in endemic areas and some of the simian T-cell lymphotropic ...
Hummel, Michael, Hoelzer, Dieter (Prof. Dr.), Michael Hummel, Thiel, Eckhard, Burmeister, Thomas, Schwartz, Stefan, Thomas Burmeister, Dieter Hoelzer, Stefan Schwartz, Eckhard Thiel   +9 more
core   +1 more source

Analysis of temporal expression of HTLV-2 reveals similarities and functional differences from HTLV-1 [PDF]

, 2011
In the present study, we developed a robust splice site-specific real-time RT-PCR method to quantitate all HTLV-2 transcripts. Results of this analysis conducted on three different infected cell lines (HTLV-2A Mo-T , C344 and HTLV-2B BJAB-Gu) showed that
Bender Cecilia, Rende Francesca, Cavallari Ilaria, C. Casoli, Alessia Cotena, I. Cavallari, A. Cotena, Cecilia Bender, Ciminale Vincenzo, Casoli Claudio, P. Ronzi, C. Bender, U. Bertazzoni, Umberto Bertazzoni, Paola Ronzi, Francesca Rende, Ilaria Cavallari, Bertazzoni Umberto, V. Ciminale, Vincenzo Ciminale, F. Rende, Ronzi Paola, Cotena Alessia, Claudio Casoli   +23 more
core   +1 more source

Reflections on Some of the Exceptional Features of HTLV-1 and HTLV-1 Research: A Perspective

Frontiers in Immunology, 2022
The report is not a review or a summary. In a manner, it is a perspective but an unusual one. It looks back to the years my colleagues and I (RG) began preparing for human retroviruses (beginning in 1970), how they evolved, and attempts to bring to light or simply to emphasize many exceptional characteristics of a retrovirus known as HTLV-1 and some ...
Gallo, Robert C., Tagaya, Yutaka
openaire   +3 more sources

HTLV-1 pathogenesis mediated by HTLV-1 bZIP factor

Uirusu, 2012
HTLV-1 is a retrovirus associated with human diseases, such as ATL or HAM/TSP. More than thirty years have passed since HTLV-1 was discovered, but the precise mechanism of HTLV-1 pathogenesis still remains elusive. HTLV-1 bZIP factor (HBZ) was reported ten years ago as a viral gene encoded in the minus strand of HTLV-1.
openaire   +3 more sources

Distribution of adult T‐cell leukaemia/lymphoma subtypes and survival outcomes across geographical regions: An international retrospective cohort study

British Journal of Haematology, EarlyView.
Summary Although adult T‐cell leukaemia/lymphoma (ATL) has a higher burden in certain world regions, outcomes have not been directly compared across regions. We conducted a multicentre cohort study comparing the distribution of ATL subtypes and overall survival (OS) across 1090 adults (≥18 years) diagnosed with ATL during 2000–2023 in Japan (n = 366 ...
Bryan Valcarcel, Atae Utsunomiya, Maki Otsuka, Masaharu Miyahara, Kenji Ishitsuka, Yasushi Takamatsu, Junji Suzumiya, Kazuo Tamura, Jule F. Vasquez, Daniel Enriquez‐Vera, Brady E. Beltran, Denisse Castro, Thanya Runciman, Henry Idrobo, Elizabeth Arrieta, Oriana Arias, Eduardo Gotuzzo, Gabriela Garrido‐Pinzás, Victor Rivera, Daniel La Rosa, Camila Peña, Lorena Fiad, Juan C. Ramos, Jose Sandoval‐Sus, Alejandro Sica, Britney N. Bell, Lucy B. Cook, Veronica Leataud, Eliana C. M. Miranda, Carlos Chiattone, Hiroo Katsuya, Luis Malpica   +31 more
wiley   +1 more source

HTLV-1 Tax-1 interacts with SNX27 to regulate cellular localization of the HTLV-1 receptor molecule, GLUT1

, 2019
An estimated 10–20 million people worldwide are infected with human T cell leukemia virus type 1 (HTLV-1), with endemic areas of infection in Japan, Australia, the Caribbean, and Africa.
Green, Patrick L, Mamuka Kvaratskhelia, Michael P Martinez, Kvaratskhelia, Mamuka, Patrick L Green, Patrick L. Green (30959), Dirksen, Wessel P, Lee Ratner, Martinez, Michael P, Nikoloz Shkriabai (659198), Ratner, Lee, Mamuka Kvaratskhelia (43017), Wessel P. Dirksen (6494765), Lee Ratner (73067), Wessel P Dirksen, Jacob Al-Saleem, Jacob Al-Saleem (659199), Al-Saleem, Jacob, Shkriabai, Nikoloz, Michael P. Martinez (6494768), Nikoloz Shkriabai   +20 more
core   +1 more source

HTLV-1 Proliferation after CD8+ Cell Depletion by Monoclonal Anti-CD8 Antibody Administration in Latently HTLV-1-Infected Cynomolgus Macaques

Microbiology Spectrum, 2023
Human T-cell leukemia virus type 1 (HTLV-1) induces chronic asymptomatic latent infection with a substantial proviral load but without significant viral replication in vivo.
Midori Nakamura-Hoshi, Takushi Nomura, Masako Nishizawa, Trang Thi Thu Hau, Hiroyuki Yamamoto, Midori Okazaki, Hiroshi Ishii, Kenzo Yonemitsu, Yuriko Suzaki, Yasushi Ami, Tetsuro Matano   +10 more
doaj   +1 more source

Development of Chimeric Antigen Receptor‐Modified NK Cells for the Immunotherapy of Adult T‐Cell Leukemia/Lymphoma

European Journal of Haematology, EarlyView.
ABSTRACT Adult T‐cell leukemia/lymphoma (ATL) is an aggressive hematological malignancy with a poor prognosis and limited therapeutic options. ATL cells exhibit aberrant surface glycosylation patterns resulting from dysregulated glycosyltransferase expression, representing a potentially tumor‐specific therapeutic target.
Yuichiro Uchida, Seigo Tateo, Masahiro Wakao, Hiroyuki Shinchi, Hayate Sawayama, Akira Fukumoto, Makoto Yoshimitsu, Yasuo Suda   +7 more
wiley   +1 more source

HTLV-1/2 proviral load by sex and age among rural population in Gabon, central Africa.

, 2018
Rectangle: Average magnitude of HTLV1/2 proviral load; Line: Median proviral load; Bar: Standard deviation. HTLV-1/2 proviral load was measured by a multiplex real-time PCR assay involving a molecular beacon probe for simultaneous detection ...
Maria Makuwa (131491), Guillaume Besson (313049), Melanie Caron (2558596), Eric Leroy (264004), Dieudonne Nkoghe (3404600), Cindy Padilla (201518), Mirdad Kazanji (136517)   +6 more
core   +1 more source