Results 71 to 80 of about 29,732,513 (224)
Biotechnology and Bioengineering, Volume 123, Issue 10, Page 2605-2612, October 2026.ABSTRACT Alpha‐1‐antitrypsin (A1AT) is a multifunctional, clinically important, high‐value therapeutic glycoprotein that can be used for the treatment of many diseases, such as A1AT deficiency, diabetes, graft‐versus‐host disease, cystic fibrosis, and various viral infections. Currently, the only U.S. food and drug administration‐approved treatment for
Frances Rocamora +12 more
wiley +1 more source
Retrovirology, 2005 Background Human T-lymphotropic virus type 1 (HTLV-1) proviral load is related to the development of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and has also been shown to be elevated in the peripheral blood in HTLV-1-infected ...
Olindo Stéphane +7 more
doaj +1 more source
Prevalence and risk factor analysis for HIV/HTLV 1/2 coinfection in Paraíba state, Brazil
Journal of Infection in Developing Countries, 2021 Introduction: Human T-lymphotropic virus (HTLV) 1 and 2 infections can lead to neurological diseases, mainly in HIV/HTLV 1 coinfected. Furthermore, HTLV 1 infection in HIV/AIDS patients has also been associated with AIDS progression.
Marcela Santos de Souza +6 more
doaj +1 more source
The HTLV-1 Virological Synapse [PDF]
Viruses, 2010 Human T-lymphotropic virus-1 (HTLV-1) spreads efficiently between T-cells via a tight and highly organized cell-cell contact known as the virological synapse. It is now thought that many retroviruses and other viruses spread via a virological synapse, which may be defined as a virus-induced, specialized area of cell-to-cell contact that promotes the ...
Nejmeddine, Mohamed +1 more
openaire +3 more sources
HTLV-1+ subjects and PBMCs examined in this study.
, 2019 HTLV-1+ subjects and PBMCs examined in this study.
Michi Miura (144400) +5 more
core +1 more source
Molecular Oncology, Volume 20, Issue 9, Page 2296-2322, September 2026.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Absence of HTLV-1/2 infection and dermatological diseases in Manaus, State of Amazonas, Brazil
Revista da Sociedade Brasileira de Medicina Tropical, 2014 Introduction The prevalence of human T-cell lymphotropic virus types 1 and 2 (HTLV-1/2) infection is heterogeneous across different populations. We tested the hypothesis that HTLV-1/2 infection occurs more often in dermatological patients.
Leny Nascimento da Motta Passos +6 more
doaj +1 more source
Functional interactions of the Tax and p13 proteins of Human T-cell Leukemia Virus Type I [PDF]
, 2013 Human T-cell leukemia virus type 1 (HTLV-1) establishes a lifelong persistent infection in humans. Approximately 3% of the infected individuals will develop adult T-cell leukemia/lymphoma (ATLL), an aggressive malignancy of mature CD4+ T-cells. The viral
Manicone, Mariangela
core
The Significance of cGAS‐STING Signaling in Response to Oncogenic Viruses
Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.ABSTRACT The cyclic GMP‐AMP synthase (cGAS)‐stimulator of interferon genes (STING) signaling pathway, as a key DNA sensor, plays a significant role in the regulation of innate immune responses. This pathway can be activated by sensing abnormal DNA, and is of great significance for resisting the invasion of pathogenic microorganisms and maintaining ...
Limei Guo +4 more
wiley +1 more source
HTLV-1 Infection and Rheumatic Diseases
Frontiers in Microbiology, 2020 Some major research and clinical questions about human T-cell leukemia virus type 1 (HTLV-1) infection and rheumatic diseases remain: (1) Does HTLV-1 infection cause rheumatic diseases?
Kunihiko Umekita, Akihiko Okayama
doaj +1 more source