Results 81 to 90 of about 107,551,550 (224)

HTLV-1 Infection and Rheumatic Diseases

Frontiers in Microbiology, 2020
Some major research and clinical questions about human T-cell leukemia virus type 1 (HTLV-1) infection and rheumatic diseases remain: (1) Does HTLV-1 infection cause rheumatic diseases?
Kunihiko Umekita, Akihiko Okayama
doaj   +1 more source

The m.14484T>C MT‐ND6 Mutation Presenting with a Hereditary Spastic‐Paraparesis Phenotype

Movement Disorders Clinical Practice, EarlyView.
Gabriel Amorelli, Christelle Nilles, Gerald Pfeffer, Matthew Joel, Davide Martino   +4 more
wiley   +1 more source

Multiple Sclerosis and Viruses: « Liaisons Dangereuses »

Reviews in Medical Virology, Volume 36, Issue 6, November 2026.
ABSTRACT Multiple sclerosis (MS) is a complex, multifactorial neurodegenerative disease with an aetiology that is still partially elusive. Several risk factors are associated with MS development including genetic predisposition and various environmental stressors; however, recently, viral infections have gained significant attention as a crucial ...
Samanta Plavina, Daniela Malakovska, Jolanta Kalnina, Ilva Trapina, Elina Leonova, Mohammed Habib, Susanne Schifmann, Jegors Paramonovs, Nikolajs Sjakste, Yegor Vassetzky, Emmanuel Drouet, Natalia Paramonova   +11 more
wiley   +1 more source

Opsoclonus‐Myoclonus‐Ataxia Revealing Underlying Neuromyelitis Optica Spectrum Disorder

Movement Disorders Clinical Practice, EarlyView.
Ana Silvia Sobreira Lima Verde, Flávia de Paiva Santos Rolim, Amanda Vale Catunda, José Orlando Ferreira Tomé Filho, Milena Sales Pitombeira, Fernanda Martins Maia Carvalho, Paula Camila Alves de Assis Pereira Matos   +6 more
wiley   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, Volume 13, Issue 10, Page 2002-2016, October 2026.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

HTLV-1, HHV-8, and SMRV specific read numbers of cell lines ordered by CCLE file names.

, 2019
HTLV-1, HHV-8, and SMRV specific read numbers of cell lines ordered by CCLE file names.
Claudia Pommerenke (150761), Hans G. Drexler (146300), Sabine A. Denkmann (732799), Cord C. Uphoff (732797)   +3 more
core   +1 more source

Glycoengineered Recombinant Alpha1‐Antitrypsin Results in Comparable In Vitro and In Vivo Activities to Human Plasma‐Derived Protein

Biotechnology and Bioengineering, Volume 123, Issue 10, Page 2605-2612, October 2026.
ABSTRACT Alpha‐1‐antitrypsin (A1AT) is a multifunctional, clinically important, high‐value therapeutic glycoprotein that can be used for the treatment of many diseases, such as A1AT deficiency, diabetes, graft‐versus‐host disease, cystic fibrosis, and various viral infections. Currently, the only U.S. food and drug administration‐approved treatment for
Frances Rocamora, Chen‐Lin Hsieh, Sanne Schoffelen, Johnny Arnsdorf, Eric A. Toth, Abdul S. Yunus, Thomas E. Cleveland IV, Sara Petersen Bjørn, Mina Ying Min Wu, Noel G. McElvaney, Bjørn Gunnar Rude Voldborg, Thomas R. Fuerst, Nathan E. Lewis   +12 more
wiley   +1 more source

HTLV-1: Persistence and pathogenesis

Virology, 2013
ContentsIntroduction. . 131HTLV-1 pathogenesis 132HTLV-1 and disease. . . 132ATL 132HAM/TSP . . 132Determinants of proviral load 132Integration and clonal expansion . . 132CD8þ T cell lysis 133The immune response to HTLV-1. . . 133Determinants of protective immunity 133Immunodominance 134‘‘Innate’’ receptors enhance the HLA class I-restricted ...
Cook, Lucy B., Elemans, Marjet, Rowan, Aileen G., Asquith, Becca   +3 more
openaire   +2 more sources

Family Aggregation of Human T-Lymphotropic Virus 1-Associated Diseases: a Systematic Review

Frontiers in Microbiology, 2016
Human T-lymphotropic virus 1 (HTLV-1) is a retrovirus that produces a persistent infection. Two transmission routes (from mother to child and via sexual intercourse) favor familial clustering of HTLV-1.
Carolina Alvarez, Carolina Alvarez, Eduardo Gotuzzo, Eduardo Gotuzzo, Anne-Mieke Vandamme, Anne-Mieke Vandamme, Kristien Verdonck, Kristien Verdonck   +7 more
doaj   +1 more source

Investigating the Distribution: Signal, Noise, and the Resolution Toolkit in Evidence‐Based Medicine

Journal of Evaluation in Clinical Practice, Volume 32, Issue 7, October 2026.
ABSTRACT Rationale, Aims and Objectives Evidence‐based medicine (EBM) manages observational noise but lacks an explicit framework for taxonomic blur: treatment‐relevant variation generated when syndromic populations mix patients differing in mechanism or treatment responsiveness. Patients present with syndromes, not resolved pathophysiological classes.
Frederick Arthur
wiley   +1 more source