Results 31 to 40 of about 27,315,508 (265)

High prevalence of bronchiectasis is linked to HTLV-1-associated inflammatory disease. [PDF]

, 2015
BACKGROUND: Human T-lymphotropic virus type 1 (HTLV-1), a retrovirus, is the causative agent of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and adult T-cell leukaemia/lymphoma (ATLL).
A Gessain, A Gessain, AH Smith, AM Vine, CR Bangham, D Weycker, E Gotuzzo, EL Murphy, F Okada, Graham P Taylor, H Kawai, H Merle, H Nakamura, IARC Monographs on the Evaluation of Carcinogenic Risk to Humans, J Crofton, JR Orland, K Nishioka, L Einsiedel, L Einsiedel, L Einsiedel, L LaGrenade, M Nagai, M Nakagawa, M Osame, M Sugimoto, M Sugimoto, MA Demontis, MG Flynn, OS Morgan, PJ McShane, S Mita, S Mori, Shohreh Honarbakhsh, T Arakaki, T Kondo, T Matsuda, T Yamashiro, W Matsuyama   +37 more
core   +1 more source

Multi-Epitope Protein as a Tool of Serological Diagnostic Development for HTLV-1 and HTLV-2 Infections

Frontiers in Public Health, 2022
A multi-epitope protein expressed in a prokaryotic system, including epitopes of Env, Gag, and Tax proteins of both HTLV-1 and HTLV-2 was characterized for HTLV-1/2 serological screening.
Gabriela de Melo Franco, Gabriela de Melo Franco, Anderson Santos da Rocha, Anderson Santos da Rocha, Laura Jorge Cox, Laura Jorge Cox, Danielle Soares de Oliveira Daian e Silva, Danielle Soares de Oliveira Daian e Silva, Débora Marques da Silveira e Santos, Débora Marques da Silveira e Santos, Marina Lobato Martins, Marina Lobato Martins, Luis Claudio Romanelli, Luis Claudio Romanelli, Ricardo Ishak, Antonio C. R. Vallinoto, Maria Rosa Q. Bomfim, Adele Caterino-de-Araujo, Jordana G. A. Coelho-dos-Reis, Jordana G. A. Coelho-dos-Reis, Flávio Guimarães da Fonseca, Edel Figueiredo Barbosa-Stancioli, Edel Figueiredo Barbosa-Stancioli   +22 more
doaj   +1 more source

HTLV-1 Tax-1 interacts with SNX27 to regulate cellular localization of the HTLV-1 receptor molecule, GLUT1 [PDF]

, 2019
An estimated 10–20 million people worldwide are infected with human T cell leukemia virus type 1 (HTLV-1), with endemic areas of infection in Japan, Australia, the Caribbean, and Africa.
Al-Saleem, Jacob, Dirksen, Wessel P, Green, Patrick L, Kvaratskhelia, Mamuka, Martinez, Michael P, Ratner, Lee, Shkriabai, Nikoloz   +6 more
core   +3 more sources

Cost-effectiveness of human T-cell leukemia virus type 1 (HTLV-1) antenatal screening for prevention of mother-to-child transmission.

PLoS Neglected Tropical Diseases, 2023
BackgroundHuman T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia-lymphoma (ATL) and HTLV-1-associated myelopathy-tropical spastic paraparesis (HAM/TSP) with a poor prognosis.
Akiko Kowada
doaj   +1 more source

Gem-induced cytoskeleton remodeling increases cellular migration of HTLV-1-infected cells, formation of infected-to-target T-cell conjugates and viral transmission [PDF]

, 2013
Efficient HTLV-1 viral transmission occurs through cell-to-cell contacts. The Tax viral transcriptional activator protein facilitates this process. Using a comparative transcriptomic analysis, we recently identified a series of genes up-regulated in HTLV-
Afonso, PV, Brady, JN, Cachat, A, Chevalier, SA, Gessain, A, Mahieux, R, Pise-Masison, CA, Turpin, J   +7 more
core   +1 more source

Telomere Length, Proviral Load and Neurologic Impairment in HTLV-1 and HTLV-2-Infected Subjects. [PDF]

, 2016
Short or damaged telomeres have been implicated in degenerative conditions. We hypothesized that analysis of telomere length (TL) in human T-cell lymphotropic virus (HTLV) infection and HTLV-associated neuropathy might provide clues to the etiology of ...
Blackburn, Elizabeth, Bruhn, Roberta, Lee, Tzong-Hae, Lin, Jue, Murphy, Edward L, Usadi, Benjamin   +5 more
core   +3 more sources

Making Visible HTLV Infection in a Non-endemic Area of Argentina

Frontiers in Medicine, 2022
In Argentina, the human T-cell lymphotropic virus type 1 (HTLV-1) infection has been documented mainly among blood banks with a prevalence of ~0.02–0.046% for Buenos Aires city, 0.8% for the northeast, and 1% for the northwest; both areas are considered ...
Federico R. Simioli, Maria B. Bouzas, Dana Mijalovsky, Maria V. Pineda, Lilia Mammana, Andrea Mangano, Andrea Mangano, Tomas A. Orduna   +7 more
doaj   +1 more source

HTLV-1 infections [PDF]

Journal of Clinical Pathology, 2000
Human T lymphotropic virus type 1 (HTLV-1) causes disabling and fatal diseases, yet there is no vaccine, no satisfactory treatment, and no means of assessing the risk of disease or prognosis in infected people. Recent research on the molecular virology and immunology of HTLV-1 shows the importance of the host's immune response in reducing the risk of ...
openaire   +2 more sources

Regulation of HTLV-1 transformation [PDF]

Bioscience Reports, 2022
AbstractHuman T-cell leukemia virus type 1 (HTLV-1) is the only identified oncogenic human retrovirus. HTLV-1 infects approximately 5–10 million people worldwide and is the infectious cause of adult T-cell leukemia/lymphoma (ATL) and several chronic inflammatory diseases, including HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP ...
Kyle J. Ernzen, Amanda R. Panfil
openaire   +2 more sources

Seroprevalence of human T-lymphotropic virus type 1 in Papua New Guinea and Irian Jaya measured using different Western blot criteria [PDF]

, 2000
Background: Endemic foci of HTLV-1 carriers have been found in the world, however, the origin of HTLV-1 in humans is still unclear. Since a distinct type of virus strain was isolated from the Solomon Islands, detailed surveys on HTLV-1 prevalence in ...
Bhatia, Krudep K., Ishida, Takafumi, Kayame, Oktovianus Wellem, Soemantri, Augustinus, Takao, Satomi   +4 more
core   +1 more source