Results 91 to 100 of about 3,180,845 (188)
Evaluation of the role of TAX, HBZ, and HTLV-1 proviral load on the survival of ATLL patients. [PDF]
Background Adult T-cell leukemia/lymphoma (ATLL) is an aggressive malignancy with very poor prognosis and short survival, caused by the human T-lymphotropic virus type-1 (HTLV-1).
Akbarin MM +8 more
europepmc +2 more sources
ABSTRACT Background and Aims Human T‐cell lymphotropic virus type 1 (HTLV‐1) is a retrovirus that is associated to adult T‐cell leukemia/lymphoma (ATLL) and HTLV‐1–associated myelopathy/tropical spastic paraparesis (HAM/TSP) as two major diseases of the virus.
Arash Letafati +8 more
wiley +1 more source
Virological and Immunological Aspects of AIDS Pathogenesis
The most common and serious problem associated with long term antiretroviral therapy is waning efficacy over time. To date. a number of studies has suggested an association between drug resistance and clinical deterioration. However.
Brian Conway, Francisco J Diaz-Mitoma
doaj +1 more source
Utility of Flow Cytometry for Prognostic Prediction in Adult T‐Cell Leukemia/Lymphoma
ABSTRACT Introduction Adult T‐cell leukemia/lymphoma (ATL) exhibits marked clinical heterogeneity; however, current classification primarily rely on morphology and laboratory findings and require further advancement. This study aimed to evaluate the roles of human T‐lymphotropic virus type 1 (HTLV‐1)–infected cell (CD4‐positive T cell) analysis system ...
Shigeo Fuji +9 more
wiley +1 more source
Nucleotide Metabolism in Health and Disease
Nucleotide metabolism, including de novo synthesis, salvage pathways, and catabolism, when dysregulated contributes to cancer, immune disorders, metabolic and urological diseases, and radiation injury. Metabolites such as adenosine, cGAMP, NAD, and cAMP and enzymes like RNR are promising therapeutic targets and biomarkers.
Xiaoying Zhao +7 more
wiley +1 more source
Unfolding Plant Defence: Endoplasmic Reticulum Stress Signalling at the Plant‐Pathogen Interface
ABSTRACT The endoplasmic reticulum (ER) stress response, a conserved proteostasis network, has emerged as a central hub that reprograms plant immunity during pathogen attack. This review synthesises how plants harness ER‐stress signalling to mount multilayered defences and how pathogens have evolved counterstrategies to subvert these pathways.
Zhe Meng +8 more
wiley +1 more source
Simian T-Leukemia Virus type 1 and Simian Foamy Virus infect non-human primates. While STLV-1, as HTLV-1, causes Adult T-cell Leukemia/lymphoma, SFV infection is asymptomatic.
S. Alais +9 more
semanticscholar +1 more source
ABSTRACT Japanese encephalitis virus (JEV), a neurotropic flavivirus and a major cause of viral encephalitis, poses a significant global health threat due to its neuroinvasive potential. Host innate immune responses, particularly those mediated by pattern‐recognition receptors such as Toll‐like receptors (TLRs) and RIG‐I–like receptors, play critical ...
Mohammad Enamul Hoque Kayesh +2 more
wiley +1 more source
Chandipura Virus: An Emerging Neurological Threat Transmitted by Sandflies in India
Chandipura virus (CHPV), a neurotropic arbovirus transmitted primarily by sandflies, has emerged as a significant public health concern in India following recurrent outbreaks with high pediatric fatality rates. This review highlights the virus's virology, transmission dynamics, clinical features, and the urgent need for improved diagnostics ...
Abrar Ahmad Zargar +2 more
wiley +1 more source

