Results 51 to 60 of about 10,657 (203)
Effect of bovine leukemia virus infection and proviral load on the systemic profile of dairy heifers during the transition period [PDF]
: This study aimed to evaluate the effect of bovine leukemia virus (BLV) on the systemic profile of naturally infected dairy heifers during the transition period. Pregnant Holstein and Jersey heifers (n=24) were distributed in pairs into two experimental
Fabrício Dias Torres +6 more
doaj +1 more source
Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leukosis, which is the most common neoplastic disease of cattle and is closely related to human T-cell leukemia viruses.
Wlaa Assi +5 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Association of Sicca Syndrome with Proviral Load and Proinflammatory Cytokines in HTLV-1 Infection
TheSjögrensyndrome has been diagnosed in patients with HTLV-1 associated myelopathy and dry mouth and dry eyes are documented in HTLV-1 carriers. However the diagnosis ofSjögrensyndrome in these subjects has been contested. In this cross-sectional study, we evaluated the role of immunological factors and proviral load, in sicca syndrome associated with
Clara Mônica Lima +7 more
openaire +3 more sources
Proviral load of symptomatic carriers vs asymptomatic HTLV-1 carriers.
Proviral load of symptomatic carriers vs asymptomatic HTLV-1 carriers.
Ariel Fridman (7961834) +11 more
core +1 more source
Introduction: Human T-cell lymphotropic virus type 1 (HTLV-1) is sexually transmitted and causes persistent infection. This virus induces activation of the immune system and production of inflammatory cytokines.
Alisson de Aquino Firmino +6 more
doaj +3 more sources
UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro +7 more
wiley +1 more source
HTLV-1/2 proviral load by sex and age among rural population in Gabon, central Africa.
Rectangle: Average magnitude of HTLV1/2 proviral load; Line: Median proviral load; Bar: Standard deviation. HTLV-1/2 proviral load was measured by a multiplex real-time PCR assay involving a molecular beacon probe for simultaneous detection ...
Maria Makuwa (131491) +6 more
core +1 more source
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth +10 more
wiley +1 more source
Long‐term follow‐up study on SIV intestinal proviral load in rhesus macaques
After experimental infection with simian immunodeficiency virus (SIV), intestinal endoscopy proved to be an easily tolerated, minimal invasive procedure to obtain biopsies from the gastrointestinal tract of rhesus macaques during all stages of disease.
Didier, Andrea +9 more
openaire +3 more sources

