Results 31 to 40 of about 142,549 (217)

Influenza D Virus: A Review and Update of Its Role in Bovine Respiratory Syndrome

Viruses, 2022
Bovine respiratory disease (BRD) is one of the most prevalent, deadly, and costly diseases in young cattle. BRD has been recognized as a multifactorial disease caused mainly by viruses (bovine herpesvirus, BVDV, parainfluenza-3 virus, respiratory ...
Miguel Ruiz, Andrea Puig, Marta Bassols, Lorenzo Fraile, Ramon Armengol   +4 more
doaj   +1 more source

Indirect detection of respiratory viruses responsible for respiratory disease in sheep

Medicina Veterinária, 2020
Respiratory disease in sheep is an important disease in sheep flocks, in which viruses are categorized as primary etiological agents. It is responsible for elevated economic losses in sheep production and new data about its occurrence and the ...
Mariane Ferreira Franco, Natália Carrillo Gaeta, Mario Augusto Reyes Alemán, Adriana Hellmeister Campos Nogueira, Ediviges Maristela Pituco, Mario Felipe Alvarez Balaro, Lilian Gregory   +6 more
doaj  

Molecular characterization of Brazilian wild-type strains of bovine respiratory syncytial virus reveals genetic diversity and a putative new subgroup of the virus

Veterinary Quarterly, 2020
Background Bovine orthopneumovirus, formerly known as bovine respiratory syncytial virus (BRSV), is frequently associated with bovine respiratory disease (BRD).
Raquel Arruda Leme, Alais Maria Dall Agnol, Luciana Carvalho Balbo, Fernanda Louise Pereira, Flávia Possatti, Alice Fernandes Alfieri, Amauri Alcindo Alfieri   +6 more
doaj   +1 more source

Bacteriological studies on calves affected with respiratory manifestations [PDF]

Journal of Veterinary Medical Research, 2019
Bovine respiratory disease (BRD) is the most common and costly diseaseaffecting beef cattle calves in the world. The objectives of this study were to put ahigh light on epidemiology of P. multocida and M.
El-Seedy F.R., Abed A.H., Hassan H.M., Nabih A.M., Khalifa E., Salem S.E.   +5 more
doaj   +3 more sources

Characterisation of the First Bovine Parainfluenza Virus 3 Isolate Detected in Cattle in Turkey

Veterinary Sciences, 2019
A respiratory disease outbreak on a cattle farm in northern Turkey produced respiratory tract symptoms and severe pneumonia symptoms in 20 calves. Eight calves died, and a lung specimen from one carcass was analysed for bacteria and for viruses of the ...
Harun Albayrak, Zafer Yazici, Emre Ozan, Cuneyt Tamer, Ahmed Abd El Wahed, Stefanie Wehner, Kristina Ulrich, Manfred Weidmann   +7 more
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Influenza C Virus in Cattle with Respiratory Disease, United States, 2016–2018

Emerging Infectious Diseases, 2018
We identified influenza C virus (ICV) in samples from US cattle with bovine respiratory disease through real-time PCR testing and sequencing. Bovine ICV isolates had high nucleotide identities (≈98%) with each other and were closely related to human ICV ...
Hewei Zhang, Elizabeth Porter, Molly Lohman, Nanyan Lu, Lalitha Peddireddi, Gregg Hanzlicek, Douglas Marthaler, Xuming Liu, Jianfa Bai   +8 more
doaj   +1 more source