Results 71 to 80 of about 27,060 (227)

Systematic Proteomic Characterization of EV‐A71‐Infected Mice Identifies Dynamic Molecular Changes and Therapeutic Targets

MedComm, Volume 7, Issue 4, April 2026.
Time‐resolved multi‐omics of EV‐A71‐infected BALB/c mice uncovered dynamic host responses, revealing rapid neutrophil extracellular traps (NETs) activation as a key event. Screened drugs (kinase inhibitors) suppressed viral replication in vitro and in vivo, suggesting the promise of targeting host phosphorylation networks as a viable antiviral strategy.
Wanjun Peng, Qiaochu Wang, Binbin Zhao, Lihong Zhang, Jing Wu, Xiaohui Wei, Na Rong, Zhaohua Wang, Kaihui Liu, Jiangfeng Liu, Juntao Yang, Jiangning Liu   +11 more
wiley   +1 more source

Occurrence in sick animals and genetic heterogeneity of Siberian isolates of bovine respiratory syncytial virus (Pneumoviridae: Orthopneumovirus; BRSV) identified in the territories of the Ural, Siberian Federal District and the Republic of Kazakhstan

Вопросы вирусологии
Introduction. Bovine respiratory syncytial virus (Pneumoviridae: Orthornavirae, Orthopneumovirus; Bovine orthopneumovirus, Bovine respiratory syncytial virus, BRSV) is one of causative agents of respiratory diseases in animals.
Alexander G. Glotov, Anton G. Yuzhakov, Tatyana I. Glotova, Alexey V. Nefedchenko, Svetlana V. Koteneva, Alina K. Komina, Elena V. Zhukova   +6 more
doaj   +1 more source

Development of a nanoparticle-assisted PCR assay for detection of bovine respiratory syncytial virus

BMC Veterinary Research, 2019
Background Bovine respiratory syncytial virus (BRSV) is a common pathogen causing respiratory disease in cattle and a significant contributor to the bovine respiratory disease (BRD) complex.
Zhankui Liu, Jianyou Li, Zeyu Liu, Jiawei Li, Zhijie Li, Chao Wang, Jianke Wang, Li Guo   +7 more
doaj   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, Volume 36, Issue 26, 30 March 2026.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, Volume 15, Issue 10, 13 March 2026.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

Intranasal administration of RSV antigen-expressing MCMV elicits robust tissue-resident effector and effector memory CD8+ T cells in the lung [PDF]

, 2017
Cytomegalovirus vectors are promising delivery vehicles for vaccine strategies that aim to elicit effector CD8+ T cells. To determine how the route of immunization affects CD8+ T cell responses in the lungs of mice vaccinated with a murine ...
Graham, B S, Moin, S M, Morabito, K M, Price, David, Redwood, A J, Ruckwardt, T R   +5 more
core   +2 more sources

High‐Throughput In Vivo Screening Using Barcoded mRNA Identifies Lipid Nanoparticles With Extrahepatic Tropism for In Situ Immunoengineering

Advanced Materials, Volume 38, Issue 13, 3 March 2026.
A high‐throughput in vivo mRNA LNP screening platform is developed and employed to screen a large library of 122 mRNA LNPs in vivo for delivery to immune, stromal, and parenchymal cells, identifying promising LNP candidates. A novel small particle flow cytometry‐based protein adsorption analysis method is utilized to interrogate protein corona ...
Alex G. Hamilton, Ajay S. Thatte, Junchao Xu, Zhangyi Luo, Hannah C. Safford, Kelsey L. Swingle, Jenna Muscat‐Rivera, Michael Kegel, Xuexiang Han, Ryann A. Joseph, Amanda M. Murray, Hannah C. Geisler, Ricardo C. Whitaker, Lulu Xue, Roman Spektor, Jilian R. Melamed, Drew Weissman, Michael J. Mitchell   +17 more
wiley   +1 more source

Seroprevalence of some bovine viral respiratory diseases among non vaccinated cattle in Saudi Arabia

Veterinary World, 2013
Aim: Four viral pathogens, bovine viral diarrhea virus (BVDV), and bovine herpes virus type 1 (BHV-1), bovine parainfluenza type 3 virus (PI-3V), bovine respiratory syncytial virus (BRSV) are mainly associated with bovine respiratory diseases that cause ...
Mohamed Abd El Fatah Mahmoud, Mohamed Rabie Yousef, Samir Mohamed Ali, Mohamed Hamad Al-Blowi   +3 more
doaj   +1 more source

Bovine Respiratory Syncytial Virus Enhances the Adherence of Pasteurella multocida to Bovine Lower Respiratory Tract Epithelial Cells by Upregulating the Platelet-Activating Factor Receptor

Frontiers in Microbiology, 2020
Coinfection by bovine respiratory syncytial virus (BRSV) and Pasteurella multocida (PM) frequently has been observed in cattle that develop severe pneumonia.
Putu Eka Sudaryatma, Putu Eka Sudaryatma, Akatsuki Saito, Akatsuki Saito, Akatsuki Saito, Hirohisa Mekata, Hirohisa Mekata, Meiko Kubo, Watcharapong Fahkrajang, Eugene Mazimpaka, Eugene Mazimpaka, Tamaki Okabayashi, Tamaki Okabayashi, Tamaki Okabayashi   +13 more
doaj   +1 more source

Intranasal immunisation with recombinant adenovirus vaccines protects against a lethal 2 challenge with pneumonia virus of mice [PDF]

, 2015
Pneumonia virus of mice (PVM) infection of BALB/c mice induces bronchiolitis leading to a fatal pneumonia in a dose-dependent manner, closely paralleling the development of severe disease during human respiratory syncytial virus infection in man, and is ...
Easton, A. J. (Andrew J.), Leppard, Keith, Maunder, Helen E., Taylor, Geraldine   +3 more
core   +1 more source