Results 81 to 90 of about 27,060 (227)

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, Volume 13, Issue 16, 18 March 2026.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Genetic replacement of surfactant protein-C reduces respiratory syncytial virus induced lung injury [PDF]

, 2013
BACKGROUND: Individuals with deficiencies of pulmonary surfactant protein C (SP-C) develop interstitial lung disease (ILD) that is exacerbated by viral infections including respiratory syncytial virus (RSV). SP-C gene targeted mice (Sftpc -/-) lack SP-C,
Albert P Senft, John E Baatz, Kristen Page, Melissa D Maxfield, Stephan W Glasser, Teah L Ruetschilling, Thomas R Korfhagen   +6 more
core   +1 more source

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

Advanced Science, Volume 13, Issue 16, 18 March 2026.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz, Niek van Hilten, Tatjana Weil, Thunchanok Thummaraj, Jeroen Methorst, Dennis Aschmann, Alexander Kros, Clarissa Read, Jasmina Gačanin, Herre Jelger Risselada, Jan Münch   +10 more
wiley   +1 more source

Serological Survey of Antibodies to Mannheimia haemolytica and Pasteurella multocida in Camelids from Argentina [PDF]

, 2017
South American camelids are a source of livestock wealth in Andean countries. In Argentina,there is little information about camelid pathogens, and most of the literature data available areseroprevalence works against virus.
Calcagno, M. L., Canellada, Andrea Mercedes, Castro, Marisa Silvia, Díaz, Ailén Magalí, Ledesma, Martin Manuel, Leoni, Juliana, Manghi, Marcela Alejandra   +6 more
core  

Immunology of bovine respiratory syncytial virus in calves

Molecular Immunology, 2015
Bovine respiratory syncytial virus (BRSV) is an important cause of respiratory disease in young calves. The virus is genetically and antigenically closely related to human (H)RSV, which is a major cause of respiratory disease in young infants. As a natural pathogen of calves, BRSV infection recapitulates the pathogenesis of respiratory disease in man ...
Guzman, Efrain, Taylor, Geraldine
openaire   +2 more sources

Heterogeneous Activated B Cell Compartments Arising Early and Transiently After SARS‐CoV‐2 Vaccination

European Journal of Immunology, Volume 56, Issue 3, March 2026.
Characterization of the early antigen‐specific B cell response post‐SARS‐CoV‐2 vaccination reveals novel activated B cell clusters, showing different phenotypes and contraction dynamics. Some short‐lived activated B cells expressed both CD71 and the extrafollicular marker CD11c.
Laura Fernandez Blanco, Lisan H. Kuijper, Laura Y.L. Kummer, Niels J.M. Verstegen, Amélie Bos, Mathieu Claireaux, Mariël C. Duurland, Tineke Jorritsma, Maurice Steenhuis, Gius Kerster, Juan J. Garcia Vallejo, Marit J. van Gils, Koos P.J. van Dam, Eileen W. Stalman, Luuk Wieske, Laura Boekel, Gertjan J. Wolbink, Sander W. Tas, Theo Rispens, Taco W. Kuijpers, Filip Eftimov, Anja ten Brinke, S. Marieke van Ham, of T2B! Immunity Against SARS‐CoV‐2 Study Group   +23 more
wiley   +1 more source

Prevalence of bovine respiratory viruses in cattle calves in Kangra district of Himachal Pradesh

Indian Journal of Animal Sciences
Respiratory diseases causing pneumonia are the 2nd leading cause of mortality in bovine calves and are primarily caused by viral pathogens. The present study was undertaken in cattle calves under twelve months of age for detecting four respiratory ...
RAHUL SINGH, RAJENDRA DAMU PATIL, PRIYANKA, RAKESH KUMAR, RAJESH KUMAR ASRANI, VIPAN KUMAR GUPTA   +5 more
doaj   +1 more source

Molecular investigation of viral agents in cattle with respiratory system problems [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi
This study was carried out to investigate viral etiology using molecular methods in cattle with respiratory system problems. The animal material of the study consisted of 200 cattle of different breeds, age and sex, which were not vaccinated against ...
Ekin Emre ERKILIÇ, Nüvit COŞKUN, Ali Haydar KIRMIZIGÜL, Volkan YILMAZ, Enes AKYÜZ, Mert SEZER   +5 more
doaj   +1 more source

Nasal Delivery of mRNA Using Thermoresponsive Gellable Aqueous Biphasic Systems

Small, Volume 22, Issue 16, 17 March 2026.
Nasal delivery of mRNA using gellable aqueous biphasic systems (ABS) represents a noninvasive alternative while reducing the need for trained professionals and cold chain storage. Composed of gelatin, PEG, and water, these thermoresponsive hydrogels ensure controlled mRNA delivery and prolonged retention at the nasal mucosa, improving transfection ...
Bojan Kopilovic, Nabila Laroui, João A.P. Coutinho, Chantal Pichon, Mara G. Freire   +4 more
wiley   +1 more source

Induction and subversion of human protective immunity: contrasting influenza and respiratory syncytial virus [PDF]

, 2018
Respiratory syncytial virus (RSV) and influenza are among the most important causes of severe respiratory disease worldwide. Despite the clinical need, barriers to developing reliably effective vaccines against these viruses have remained firmly in place
Ascough, SC, Chiu, C, Paterson, S
core   +2 more sources