Results 111 to 120 of about 814,199 (298)

Smoking Promotes AT2 Cell Senescence and Exacerbates Pulmonary Fibrosis by Downregulating POT1 via Integratively Inducing CpG Methylation and MECP2‐Mediated FOXP2 Transcriptional Binding Inhibition

open access: yesAging Cell, EarlyView.
Smoking is one of the major causes of pulmonary fibrosis (PF), and treatment options for PF are limited. We show that POT1 is decreased in PF patients and mice, especially in smoke exposure, and investigate its contributions to PF progression from protecting AT2 cell senescence to fibrosis. AAV9‐mediated restoration of POT1 prevents PF.
Mengkun Shi   +9 more
wiley   +1 more source

Bovine Tuberculosis and Badger Control in Britain: Science, Policy and Politics

open access: yes, 2017
Bovine tuberculosis (bovine TB) is the most economically important animal health policy issue in Britain. The problem of what to do about badgers has plagued successive governments since a dead badger was discovered with bovine TB in 1971.
S. McCulloch, M. Reiss
semanticscholar   +1 more source

Single‐Nucleus Transcriptomics Uncovers Xaf1‐Driven PANoptosis as a Therapeutic Target in Aminoglycoside‐Induced Hearing Loss

open access: yesCell Proliferation, EarlyView.
Neomycin induces increased expression of Xaf1 in cochlear HCs, triggering PANoptosis, which encompasses pyroptosis, apoptosis and necroptosis (left). Targeted Xaf1 knockdown in HCs through gene therapy can significantly inhibit the occurrence of PANoptosis in HCs (right).
Xinlin Wang   +10 more
wiley   +1 more source

Prevalence and herd-level risk factors of bovine tuberculosis in the State of Goiás, Brazil

open access: yesSemina: Ciências Agrárias, 2016
Bovine tuberculosis results in economic losses in livestock production and poses a risk to public health. This study aimed to characterize the epidemiological status of bovine tuberculosis in adult cows in the state of Goiás, Brazil.
Willian Vilela Rocha   +12 more
doaj   +1 more source

Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): bovine tuberculosis

open access: yesEFSA journal. European Food Safety Authority, 2017
Bovine tuberculosis has been assessed according to the criteria of the Animal Health Law (AHL), in particular criteria of Article 7 on disease profile and impacts, Article 5 on the eligibility of bovine tuberculosis to be listed, Article 9 for the ...
Simon More   +24 more
semanticscholar   +1 more source

Sources of Tuberculous Infection in an Area Containing Bovine Tuberculosis [PDF]

open access: green, 1956
D. F. Van Zwanenberg   +3 more
openalex   +1 more source

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