Results 41 to 50 of about 38,570 (247)

Sensitive detection systems for infectious agents in xenotransplantation*

Xenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. II. Effect of Bovine Viral Diarrhea Virus on the Endometrial Response to Lipopolysaccharide [PDF]

, 2015
Infection with noncytopathic bovine viral diarrhea virus (ncpBVDV) is associated with uterine disease and infertility. This study investigated the influence of ncpBVDV on immune functions of the bovine endometrium by testing the response to bacterial ...
Abudureyimu, A, Anstaett, O L, Brownlie, J, Cheng, Z R, Fouladi-Nashta, A A, Oguejiofor, C F, Wathes, D C   +6 more
core   +2 more sources

Buoyant Density of Bovine Viral Diarrhea Virus

Experimental Biology and Medicine, 1972
SummaryBovine viral diarrhea virus (BV DV), strain NADL, was purified by removing extracellular fluid from infected cultures at 96 hr postinoculation and clarifying by low speed centrifugation. Clarified fluid was concentrated by centrifugation onto a two-step 20-50% sucrose discontinuous gradient.
J B, Parks, R F, Pritchett, Y C, Zee
openaire   +2 more sources

Diagnostics of dairy and beef cattle diarrhea. [PDF]

, 2012
Calf diarrhea is a multifactorial disease related to a combination of host and pathogen factors. The most common pathogens found in diarrheic calves are cryptosporidium, rotavirus, coronavirus, Salmonella, attaching and effacing E coli and F5 (K99 ...
Blanchard, Patricia Carey
core   +1 more source

PLASMD BEARING A CDNA COPY OF THE GENOME OF BOVINE VIRAL DIARRHEA VIRUS, CHIMERIC DERIVATIVES THEREOF, AND METHOD OF PRODUCING AN INFECTIOUS BOVINE WRAL DARRHEAVIRUS USING SAD PLASMID [PDF]

, 1999
A plasmid bearing a cDNA copy of the genome of bovine viral diarrhea virus (BVDV), chimeric derivatives of the plasmid and a method of producing an infectious bovine viral diarrhea virus using the plasmid are disclosed. The invention relates to a plasmid
Donis, Ruben O., Vassilev, Ventzislav B.
core   +1 more source

Hierarchically Engineered Multi‐Enzyme Nanoreactors for in vitro Drug Biosynthesis and Pathway Transplantation Into Cells

Advanced Materials, EarlyView.
A hierarchically structured metal–organic framework (eMIL) is shown to host the complete six‐enzyme biosynthesis pathway for the anti‐cancer pigment violacein, reshaping reaction dynamics and multiplying in vitro yields. eMIL nanoreactors deliver this reconstituted bacterial multi‐protein system into mammalian cells, where cell‐derived substrates and ...
Ainur Sharip, Somayah S. Qutub, Manar M. Farooqui, Walaa Baslyman, Nida Khalfay, Lukman O. Alimi, Patricia Lopez Sanchez, Lingyun Zhao, Milena Chernyshevskaia, Giovanni Colombo, Niveen M. Khashab, Stefan T. Arold, Raik Grünberg   +12 more
wiley   +1 more source

Specific Inhibition of Bovine Viral Diarrhea Virus Replicase [PDF]

Journal of Virology, 2003
ABSTRACT Compound-1453 was identified and characterized as a specific inhibitor of bovine viral diarrhea virus (BVDV). The concentration of compound-1453 which results in 50% protection from virus-induced cytopathic effect is ∼2.2 μM, with a therapeutic index of 60, and it is not active against a panel of RNA and DNA viruses.
Jin-Hua, Sun, Julie A, Lemm, Donald R, O'Boyle, Jason, Racela, Richard, Colonno, Min, Gao   +5 more
openaire   +2 more sources

Assessment of two essential elements of BVDV control on selected Flemish dairy and beef farms [PDF]

, 2013
Bovine viral diarrhea virus (BVDV) is one of the most important viruses to cause disease in cattle worldwide. The virus is endemically present in Belgium. Clinical diagnosis of BVDV infection is difficult.
Booth, Richard, De Vliegher, Sarne, Deprez, Piet, Dewulf, Jeroen, Laureyns, Jozef, Pfeiffer, Dirk, Sarrazin, Steven   +6 more
core  

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Experimental infection of reindeer with bovine viral diarrhea virus

Rangifer, 1990
Two 8-month reindeer (Rangifer tarandus) and a 1-month-old Hereford-Holstein calf (Bos taurus) were inoculated intranasally with the Singer (cytopathogenic) strain of bovine viral diarrhea (BVD) virus.
J.K. Morton, J.F. Evermann, R.A. Dieterich   +2 more
doaj   +1 more source