Results 41 to 50 of about 1,649,716 (257)

Reproductive Impact following Controlled Introduction of Bovine Viral Diarrhea Virus

open access: yes, 2010
The reproductive impact following controlled introduction of animals persistently infected (PI) with bovine viral diarrhea virus (BVDV) was evaluated in BVDV-naïve ...
Marley, M. S. D.   +5 more
core   +1 more source

Bovine Viral Diarrhea Virus Testing Options

open access: yes, 2003
A review of bovine viral diarrhea virus (BVDV) dynamics is followed by a review of test efficiency measures. BVDV diagnostic challeneges are then discussed with attention to its pathogenesis during pregnancy and fetal effects.
Slenning, Barrett D.
core   +1 more source

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

open access: yesAdvanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon   +27 more
wiley   +1 more source

Experimental infection of reindeer with bovine viral diarrhea virus

open access: yesRangifer, 1990
Two 8-month reindeer (Rangifer tarandus) and a 1-month-old Hereford-Holstein calf (Bos taurus) were inoculated intranasally with the Singer (cytopathogenic) strain of bovine viral diarrhea (BVD) virus.
J.K. Morton   +2 more
doaj   +1 more source

SPSB1 Promotes Subcutaneous Adipose Hyperplasia in Facial Port‐Wine Stains by Controlling HDAC1 Degradation and Stability Through Two Distinct Proteolytic Pathways

open access: yesAdvanced Science, EarlyView.
In PWS‐ASPCs, FOSL1 drives the expression of SPSB1. SPSB1, as part of the ESC complex, further binds to HDAC1 and promotes K29‐linked and K48‐linked polyubiquitination of HDAC1. These modifications facilitate the degradation of HDAC1 through the ALP and UPS pathways, respectively.
Hongrui Chen   +5 more
wiley   +1 more source

Prevalence of antibodies to four different rotavirus strains in different age groups of cattle [PDF]

open access: yes, 1990
Neutralizing antibody titers to four bovine rotavirus strains, representing three serotypes, were measured in 160 sera from cattle of different age groups.
Sidoti, Josette   +3 more
core   +1 more source

Bovine Viral Diarrhea Virus Infections in Commingled and Transported Calves: Fall 2000 Study and Summary of a Three-year Study

open access: yes, 2001
Bovine viral diarrhea virus (BVDV) infections, in both persistently infected (PI) and/or acutely infected calves, were investigated in commingled and transported calves. Other viral infections such as bovine herpesvirus-1 (BHV), parainfluenza-3 virus (Pl-
Confer, A. W.   +9 more
core   +1 more source

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

open access: yesAdvanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie   +12 more
wiley   +1 more source

A novel approach to bovine viral diarrhea virus surveillance

open access: yes, 2013
Bovine viral diarrhea virus (BVDV) causes significant economic loss in both the beef and dairy cattle industries. A major factor in the perpetuation of the virus in a herd of cattle is the presence of persistently infected (PI) animals. They continuously
Marley, M. S. D.   +3 more
core   +1 more source

Deltacoronavirus Modulates circRNA cGLIS3 Metabolism to Evade Host Antiviral Response

open access: yesAdvanced Science, EarlyView.
This study reveals that both deltacoronavirus nucleocapsid protein and host RNA binding protein IGF2BP2 promote circular RNA GLIS3 (cGLIS3) biogenesis by binding to GLIS3 pre‐mRNA. The m6A modification‐mediated cGLIS3‐IGF2BP2 interaction weakens RNase L‐mediated degradation of cGLIS3 while facilitates a ubiquitin‐dependent degradation of IGF2BP2, thus ...
Liuyang Du   +10 more
wiley   +1 more source

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