Results 71 to 80 of about 69,319 (240)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Secret Shopping is an Effective Tool for Identifyings in Library User Experience Local Pattern

open access: yesEvidence Based Library and Information Practice, 2016
A Review of: Boyce, C. M. (2015). Secret shopping as user experience assessment tool. Public Services Quarterly, 11(4), 237-253. doi:10.1080/15228959.2015.1084903 Objective – To assess library user experience (UX) at two entry-level service desks to ...
Kelley Wadson
doaj  

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Comparison of the adhesion performances of traditional and new generation adhesives used in the making of Turkish bows

open access: yesTurkish Journal of Forestry
From primitive societies to today's modern armies, mankind has engaged in competition and warfare since its existence, developing various weapon systems for prevailing in these conflicts.
Oktay Gönültaş, Salih Parlak
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

The Impact of Baseplate Bow on Vacuum Reflow Soldering

open access: yesKongzhi Yu Xinxi Jishu, 2011
The impact of IGBT baseplate bow on reflow soldering is analyzed. And the process parameters are adjusted to eliminate the influence of baseplate bow on soldering quality.
曾雄, 张泉
doaj  

Small Arms of the Scythians. On the Time of Sigmoid Bow Appearance in Eastern Europe

open access: yesВестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2015
Horse archers well-known in the ancient world used composite sigmoid bows for shooting (archery), the specific constructive features of which have been studied by the researchers.
Lukyashko Sergey Ivanovich
doaj   +1 more source

Business Plan

open access: yes
Bow Valley College advances transformative education, launching careers to new ...
Bow Valley College
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

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