Results 241 to 250 of about 147,886 (288)

Comparing low volume versus intermediate volume bowel preparation and their impact on work and tolerability: an open-label, noninferiority randomized controlled trial. [PDF]

Endoscopy
van Riswijk MLM, Indemans FA, Hawinkels K, Schreuder RM, Wildeman L, Tan ACITL, Siersema PD.   +6 more
europepmc   +1 more source

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

Acute Bowel Perforation Post-Bowel Preparation in a Patient with Connective Tissue Disease. [PDF]

Eur J Case Rep Intern Med
Brijawi O, Jude S, Hartman E, Fox R, Kemei A, Chakan M.   +5 more
europepmc   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Western Diet Inhibits FUT7‐Mediated Treg Intestinal Homing to Disrupt the Homeostasis of Intestinal Epithelial Cells in Crohn's Disease

Advanced Science, EarlyView.
In this study, we constructed a nanoparticle that was CD4 antibody‐mediated targeted, Fut7‐expressing plasmid‐loaded cationic liposome, namely CD4‐LDP‐Fut7. Upregulation of Fut7 expression in Tregs by using CD4‐LDP‐Fut7 can increase Treg homing to the intestine, thereby facilitating repair of the intestinal epithelial barrier and inhibiting ...
Qian Zhou, Xianfei Wang, Teng Ben, Chunping Zhu, Xinlong Lin, Yinmu Li, Xinyue Zhang, Yeling Chen, Yuchen Xuan, Huaiwen Chen, Ke Liu, Fang Wu, Yuexin Ren, Gao Tan   +13 more
wiley   +1 more source

Effect of chewing gum combined with WeChat-enhanced instruction on bowel preparation in constipated patients: a randomized-controlled trial. [PDF]

Gastroenterol Rep (Oxf)
Gao C, Zou D, Wang W, Li Y, Han J, Su D, Qi X.   +6 more
europepmc   +1 more source

A randomized, controlled trial of oral sulfate solution versus polyethylene glycol for bowel preparation for colonoscopy. [PDF]

BMC Gastroenterol
Xie DL, Fan JH, Fan CJ, Gao YH, Cheng JP.   +4 more
europepmc   +1 more source

The Fecal Microbiome of IBD Patients Is Less Divertible by Bowel Preparation Compared to Healthy Controls: Results From a Prospective Study. [PDF]

Inflamm Bowel Dis
Blesl A, Binder L, Halwachs B, Baumann-Durchschein F, Fürst S, Constantini-Kump P, Wenzl H, Gorkiewicz G, Högenauer C.   +8 more
europepmc   +1 more source

Derivation and validation of a prediction model for inadequate bowel preparation in Chinese outpatients. [PDF]

Sci Rep
Yin H, Wang Y, Wang H, Li T, Xu X, Li F, Huang L.   +6 more
europepmc   +1 more source

Bowel preparation before colonoscopy: Consequences, mechanisms, and treatment of intestinal dysbiosis. [PDF]

World J Gastroenterol
Zheng ZL, Zheng QF, Wang LQ, Liu Y.
europepmc   +1 more source