Results 51 to 60 of about 12,165 (138)

Design, development and optimization of gastro-retentive floating in-situ gels loaded with carvedilol microspheres using response surface methodology

Acta Marisiensis - Seria Medica
Aim: The goal of this study was to formulate and optimize gastro-retentive floating in-situ gel comprising optimized microspheres by Box-Behnken design.
Kukati Latha, Rahman Aisha, Fatima Aymen, Menon Vyshak R, Lakshmi SVVNSM   +4 more
doaj   +1 more source

Optimization of bioactive compounds extraction from Rosa canina L. pseudofruit through the action of two hydrolytic enzyme preparations

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKROUND The pseudo‐fruit of Rosa canina L. is a rich source of bioactive compounds with antioxidant, anti‐inflammatory, anti‐cancer, anti‐diabetic, anti‐aging, and antimicrobial activities. The aim of the present study is the optimization of a green process based on the action of two hydrolytic enzyme preparations, namely Pectinex® Ultra ...
Zafeiria Lemoni, Styliani Kalantzi, Theopisti Lymperopoulou, Andromachi Tzani, Georgios Stavropoulos, Anastasia Detsi, Diomi Mamma   +6 more
wiley   +1 more source

Nanostructured lipid carriers and natural deep eutectic solvents: a highly advantageous combination for the encapsulation of curcumin

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Curcumin is a naturally derived polyphenol known for its potent biological properties. Its therapeutic potential, however, is hindered by low bioavailability. Nanostructured lipid carriers (NLCs) have emerged as advanced delivery systems to overcome such limitations. Natural deep eutectic solvents (NADESs) have garnered attention as
Kyriaki Safari, Ioanna Pitterou, Marianthi Miliaronikolaki, Nikolaos Paraskevopoulos, Andromachi Tzani, Anastasia Detsi   +5 more
wiley   +1 more source

Circulant Matrix‐Based Box–Behnken Designs With Economic Run Sizes

Quality and Reliability Engineering International, EarlyView.
ABSTRACT We introduce Circulant Matrix‐Based Box–Behnken Designs (CBBDs), a new class of three‐level, second‐order response surface designs constructed using circulant matrix structures. These designs satisfy an enhanced orthogonal minimally aliased (OMA∗${\rm OMA}^*$) property: they retain the classical OMA property—where main effects are orthogonal ...
Tung‐Dinh Pham, Nam‐Ky Nguyen
wiley   +1 more source

Construction of an O2‐responsive engineering bioreactor for enhanced indole‐3‐propionic acid production and deoxynivalenol detoxification

Responsive Materials, EarlyView.
An oxygen‐responsive living bioreactor was engineered via interspecies protoplast fusion, converting oxygen from an inhibitory stress into a programmable signal for sustained indole‐3‐propionic acid (IPA) production. This genetically encoded bioreactor enables robust aerobic operation and therapeutic efficacy of deoxynivalenol detoxification in vivo ...
Ning Ma, Jiakun Shen, Kun Cai, Wenxi Zhao, Chuan Feng, Xingyao Wang, Yangyang Liu, Dongyan Zhang, Xi Ma   +8 more
wiley   +1 more source

Optimization of Selenite Removal by Lactobacillus sp. Tra cheese 6 Using Box-Behnken Design [PDF]

Journal of Kerman University of Medical Sciences, 2016
Background & Aims: High concentrations of selenite have carcinogenetic, cytotoxic and genotoxic effects. Therefore, removal of this toxic pullutant from the environment has a particular importance in maintaining public health. In this study, with the aim
Morahem Ashengroph, Davoud Saedi
doaj  

Tunable Natural Deep Eutectic Solvents‐Driven Fractionation of Olive Pomace in an Integrated Biorefinery: Linking Lignin Structural Tailoring to Carbohydrate Valorization and Biopolymer Production

ChemSusChem, Volume 19, Issue 13, 14 July 2026.
Microwave‐conditioned olive pomace was fractionated with deep eutectic solvents (DESs) spanning acidic, neutral, alkaline, and chemo‐enzymatic regimes. The alkaline DES provided the best balance between delignification and carbohydrate preservation, yielding a fermentable glucose/xylose stream suitable for Haloferax mediterranei fermentation and poly(3‐
Ivelina Ivaylova Dzhambazova, Maria Laura Alfieri, Lucia Panzella, Ozge Sakyan Demirkol, Fabio De Stefano, Cinzia Pezzella, Simona Varriale   +6 more
wiley   +1 more source

Optimal model‐based design of experiments for parameter precision: Supercritical extraction case

The Canadian Journal of Chemical Engineering, Volume 104, Issue 7, Page 3775-3795, July 2026.
Abstract This study investigates the process of chamomile oil extraction from flowers. A parameter‐distributed model consisting of a set of partial differential equations is used to describe the governing mass transfer phenomena in a cylindrical packed bed with solid chamomile particles under supercritical conditions using carbon dioxide as a solvent ...
Oliwer Sliczniuk, Pekka Oinas
wiley   +1 more source

Development of Hybrid Optimization for Drilling Performance in Magnesium Alloy AM60 Using Biodegradable MQL and Taguchi–MABAC Approach

Engineering Reports, Volume 8, Issue 7, July 2026.
This study optimizes drilling performance in magnesium alloy AM60 using biodegradable MQL and a hybrid Taguchi–MABAC approach. It demonstrates that biodegradable MQL significantly improves material removal rate, surface finish, and tool wear, offering a sustainable alternative to traditional lubricants for precision machining in aerospace and ...
S. P. Sundar Singh Sivam, Venugopal Gurusamy Umasekar, Stalin Kesavan, A. Johnson Santhosh   +3 more
wiley   +1 more source

LOGICAL AND EXPERIMENTAL DESIGN FOR PHENOL DEGRADATION USING IMMOBILIZED ACINETOBACTER SP. CULTURE

International Islamic University Malaysia Engineering Journal, 2010
Phenol degradation processes were conducted through a series of enzymatic reactions effects and is affect by different components of the microbial metabolic flux.
Amro Abd Al Fattah Amara, Soheir R. Salem   +1 more
doaj   +1 more source