Results 31 to 40 of about 12,165 (138)

Design Optimization of Soft Fabric Pneumatic Actuators

Advanced Intelligent Systems, EarlyView.
This study presents a systematic optimization framework for elongating and bending fabric‐based soft pneumatic actuators. After a preliminary design‐space reduction, the framework minimizes energy consumption under mechanical performance constraints by integrating validated finite element modeling with statistical surrogate models. Optimal designs were
Grigorios M. Chatziathanasiou, Konstantina Tsintzira, Panagiotis Polygerinos   +2 more
wiley   +1 more source

Sustainable levulinic acid production from inulin via hydrothermal conversion

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract This study investigates the hydrothermal conversion of inulin using potassium pyrosulfate to levulinic acid (LA). The Box–Behnken design approach was applied to optimize the conversion parameters and analyze the interactions influencing LA yield.
Gwi‐Taek Jeong
wiley   +1 more source

Dynamic, Unconstrained Optimization of Secreted Enzyme Production in Fed‐Batch Fermentation Using Reinforcement Learning

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Reinforcement learning (RL) has been used to control a wide range of dynamic processes, especially ones that are too complex to model well or have stochastic environmental perturbations. Fed‐batch fermentations are subject to changes in starting cell growth rates and process variations that can affect cell growth and secreted target production.
Sai Harish Uthravalli, Sakib Ferdous, J. Michael Hess, Nigel F. Reuel   +3 more
wiley   +1 more source

Eudragit®‐engineered pH‐responsive probiotic microspheres with enhanced gastrointestinal resistance and prolonged storage stability for inflammatory bowel disease therapy

BMEMat, EarlyView.
This study reports the development of AMS@Eud core‐shell microspheres, combining calcium alginate and pH‐responsive Eudragit® L100, which exhibit exceptional gastrointestinal resistance and long‐term storage stability (only 5.28%–9.09% viability loss over 35 days at 4–25°C), and effectively alleviate inflammatory bowel disease via gut microbiota ...
Ming Teng, Xiaomin Luo, Peng Zhang, Chen Yang, Yuniel Ma, Xinhua Liu   +5 more
wiley   +1 more source

Optimization of bioethanol production from simultaneous saccharification and fermentation of pineapple peels using Saccharomyces cerevisiae

Journal of Applied Sciences and Environmental Management, 2018
In this study, bioethanol production from the simultaneous saccharification and fermentation (SSF) of pineapple peels using cellulase and Saccharomyces cerevisiae was investigated. A three-factor Box-behnken design (BBD) and response surface methodology
O Oiwoh, B.V. Ayodele, N.A. Amenaghawon, C.O. Okieimen   +3 more
doaj   +3 more sources

Optimization of Combined Pre-Treatment Process for Bleaching of Cotton Woven Fabric Using Box–Behnken Design

Journal of Natural Fibers
The conventional bleaching process for cotton woven fabrics is characterized by high consumption of chemicals, water, and energy, resulting in significant environmental impact through elevated energy use and wastewater discharge.
Bantamlak Birlie Kassie, Habtamu Fentahun, Tekalgn Mamay Daget   +2 more
doaj   +1 more source

Optimization of Physical and Cultural Conditions of Fibrinolytic Enzyme from Bacillus altitudinis S-CSR 0020

Journal of Pure and Applied Microbiology, 2018
The main aim of this work was optimization of physical conditions as well as medium components for the maximum production of fibrinolytic enzyme. A fibrinolytic enzyme producing organism was isolated from soil and identified as Bacillus altitudinis ...
K.V. Smitha, B.V. Pradeep
doaj   +1 more source

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source

Status and future of recombinant adeno‐associated virus vector manufacturing

Biotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

Antisolvent crystallization of lithium hydroxide monohydrate: Significant factors and kinetics analysis

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Crystallization is the final stage in lithium hydroxide monohydrate (LiOH · H2O) production, and antisolvent crystallization offers a lower‐energy route compared with evaporative methods. In this study, we investigated bench‐scale ethanol‐based antisolvent crystallization of LiOH · H2O, and identified the significant impact parameter via a ...
Chentao He, Liuyin Xia
wiley   +1 more source