Results 11 to 20 of about 13,470,210 (237)

Box–Behnken Design of Experiments of Polycaprolactone Nanoparticles Loaded with Irinotecan Hydrochloride

Pharmaceutics, 2023
Background: The Box–Behnken design of experiments (BBD) is a statistical modelling technique that allows the determination of the significant factors in developing nanoparticles (NPs) using a limited number of runs.
Basant Salah Mahmoud, Christopher McConville   +1 more
doaj   +2 more sources

Pomegranate Flower Extract—The Health-Promoting Properties Optimized by Application of the Box–Behnken Design

Molecules, 2022
Herbal raw materials with antidiabetic activity can be a valuable support to therapy. An optimized extraction process allows for the best possible health-promoting effect.
Anna Gościniak, Aleksandra Bazan-Woźniak, Robert Pietrzak, Judyta Cielecka-Piontek   +3 more
doaj   +2 more sources

Methods for experimental design, central composite design and the Box–Behnken design, to optimise operational parameters: A review

Acta alimentaria, 2023
In recent years response surface analysis has been increasingly used to optimise membrane separation. It has many advantages, such as reducing the number of experiments to be performed, which requires lower energy consumption and significantly less ...
N. Szpisják-Gulyás, Aws N. Al-Tayawi, Zs. H. Horváth, Z. László, S. Kertész, C. Hodúr   +5 more
semanticscholar   +1 more source

Design and optimization of curcumin loaded nano lipid carrier system using Box-Behnken design.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021
Herbal antioxidant like curcumin holds great potential to treat neurodegenerative disease like Alzheimer's disease. However, its therapeutic potency is obstructed due to rapid metabolism, poor solubility, GI susceptibility, enzymatic degradation and ...
Mukta Agrawal, S. Saraf, Madhulika Pradhan, Ravish J. Patel, Gautam Singhvi, Ajazuddin, A. Alexander   +6 more
semanticscholar   +1 more source

Process Optimization of Biodiesel from Used Cooking Oil in a Microwave Reactor: A Case of Machine Learning and Box–Behnken Design

ChemEngineering, 2023
In the present investigation, response surface methodology (RSM) and machine learning (ML) are applied to the biodiesel production process via acid-catalyzed transesterification and esterification of triglyceride (TG). In order to optimize the production
A. Buasri, Phensuda Sirikoom, Sirinan Pattane, Orapharn Buachum, V. Loryuenyong   +4 more
semanticscholar   +1 more source

Extraction of Anthocyanins and Total Phenolic Compounds from Acai (Euterpe oleracea Mart.) Using an Experimental Design Methodology. Part 2: Ultrasound-Assisted Extraction [PDF]

, 2020
Two optimized methods for ultrasound-assisted extraction were evaluated for the extraction of two types of acai bioactive compounds: Total anthocyanins (TAs) and total phenolic compounds (TPCs).
Aliaño González, María José, Ayuso Vilacides, Jesús, Carrera Fernández, Ceferino Adrián, Espada Bellido, Estrella, Fernández Barbero, Gerardo, Ferreiro González, Marta, Palma Lovillo, Miguel, Álvarez Saura, José Ángel   +7 more
core   +1 more source

Honokiol-Loaded Nanoemulsion for Glioblastoma Treatment: Statistical Optimization, Physicochemical Characterization, and an In Vitro Toxicity Assay

Pharmaceutics, 2023
Background: Glioblastoma (GBM) is an extremely invasive and heterogenous malignant brain tumor. Despite advances in current anticancer therapy, treatment options for glioblastoma remain limited, and tumor recurrence is inevitable.
Aleksandra Gostyńska, Joanna Czerniel, Joanna Kuźmińska, Jakub Brzozowski, Aleksandra Majchrzak-Celińska, Violetta Krajka-Kuźniak, Maciej Stawny   +6 more
doaj   +1 more source

Zeolite Waste Characterization and Use as Low-Cost, Ecofriendly, and Sustainable Material for Malachite Green and Methylene Blue Dyes Removal: Box–Behnken Design, Kinetics, and Thermodynamics

Applied Sciences, 2022
This study investigated the potential of 4A zeolite, named4AZW in this work, generated by natural gas dehydration units as solid waste after several treatment cycles, as a low-cost adsorbent to separately remove two cationic dyes, methylene blue (MB) and
Ali Imessaoudene, Sabrina Cheikh, J. Bollinger, Lazhar Belkhiri, Ammar Tiri, A. Bouzaza, A. El Jery, A. Assadi, A. Amrane, Lotfi Mouni   +9 more
semanticscholar   +1 more source

Optimizing PHB and Protease Production by Box Behnken Design

International Islamic University Malaysia Engineering Journal, 2013
Mixed culture is more suitable to adapt more flexible fermentation process and produce different product simultaneously. In this study a mixed Bacillus culture was investigated for their ability to produce the bioplastic "Polyhydroxybutyrate" and both of
Amro Abd al fattah Amara
doaj   +1 more source

Response-surface-model-based system sizing for nearly/net zero energy buildings under uncertainty [PDF]

, 2018
Properly treating uncertainty is critical for robust system sizing of nearly/net zero energy buildings (ZEBs). To treat uncertainty, the conventional method conducts Monte Carlo simulations for thousands of possible design options, which inevitably leads
Cheng, Y, Huang, P, Lin, Z, Oladokun, MO, Sun, Y, Zhang, S   +5 more
core   +2 more sources