Results 1 to 10 of about 12,188 (152)

Optimizing PHB and Protease Production by Box Behnken Design

International Islamic University Malaysia Engineering Journal, 2013
Mixed culture is more suitable to adapt more flexible fermentation process and produce different product simultaneously. In this study a mixed Bacillus culture was investigated for their ability to produce the bioplastic "Polyhydroxybutyrate" and both of
Amro Abd al fattah Amara
doaj   +3 more sources

Formulation and Systematic Optimisation of Polymeric Blend Nanoparticles via Box–Behnken Design [PDF]

Pharmaceutics
Background/Objectives: Despite the advantages of polycaprolactone (PCL) for drug delivery, it still lacks effective approaches to enhance its encapsulation of drugs.
Basant Salah Mahmoud, Christopher McConville   +1 more
doaj   +2 more sources

Box–Behnken design approach for optimizing the removal of non-steroidal anti-inflammatory drugs from environmental water samples using magnetic nanocomposite [PDF]

Scientific Reports
This study investigated the removal of naproxen (NAP) and diclofenac (DIC) from aqueous solutions using an Fe3O4/ZnO/GO magnetic composite. The effects of solution pH, ultrasonic irradiation time, FZG composite amount, and initial drug concentration were
Chuanyong Yan, Ying Zhang, Li Feng
doaj   +2 more sources

Box–Behnken Design of Experiments of Polycaprolactone Nanoparticles Loaded with Irinotecan Hydrochloride

Pharmaceutics, 2023
Background: The Box–Behnken design of experiments (BBD) is a statistical modelling technique that allows the determination of the significant factors in developing nanoparticles (NPs) using a limited number of runs.
Basant Salah Mahmoud, Christopher McConville   +1 more
doaj   +3 more sources

Optimizing blended cement concrete strength using the Box-Behnken design technique [PDF]

Scientific Reports
A properly optimized concrete mix design yields the required workability and strength for the fresh and hardened concrete to sustain desired loads and stresses over time, preventing premature failure. Thus, it is imperative to investigate the behavioural
Solomon Oyebisi, Mahaad Issa Shammas, Mohammed Seyam, Bonga Praisegod Khuzwayo   +3 more
doaj   +2 more sources

Optimization and Synthesis of Nano-Niosomes for Encapsulation of Triacontanol by Box–Behnken Design [PDF]

Molecules
Triacontanol is a long-chain primary alcohol derived from policosanol, known for its diverse biological activities, including functioning as a plant growth regulator and exhibiting anti-inflammatory and antitumoral effects. However, its application is limited due to its high hydrophobicity, resulting in poor absorption and reduced therapeutic ...
Alfredo Amaury Bautista Solano, Gloria Dávila-Ortiz, María de Jesús Perea-Flores, Alma Leticia Martínez-Ayala   +3 more
openaire   +4 more sources

OPTIMAL DESIGN OF CRANK BASED ON BOX-BEHNKEN METHOD

Jixie qiangdu, 2017
Parametrically building the crank 3D model by Solid Works and doing the FEA by Simulation. Select six parameters and take maximum stress as constraints to solve minimum volume of the structure. Using BBD to optimize the structure and finish 49 iterations.
CHEN HongWu, TIAN Cheng, PENG CongCong
doaj   +1 more source

Optimization by Box–Behnken design for environmental contaminants removal using magnetic nanocomposite [PDF]

Scientific Reports
In this study, a CoO–Fe2O3/SiO2/TiO2 (CIST) nanocomposite was synthesized and utilized as an adsorbent to remove methylene blue (MB), malachite green (MG), and copper (Cu) from aqueous environments.
Luis Buenaño, Eyhab Ali, Ahmed Jafer, Shaima Haithem Zaki, Fathi Jihad Hammady, Salima Baqir Khayoun Alsaadi, Manal Morad Karim, Montather F. Ramadan, Alaa A. Omran, Ahmed Alawadi, Ali Alsalamy, Ali Kazemi   +11 more
doaj   +2 more sources

Bio-oil production from ripe pawpaw seeds and its optimal output: Box-Behnken Design and Machine Learning approach

Scientific African, 2023
The purpose of this study is to use ripe pawpaw seeds for a rapid Soxhlet extractor process with n-hexane to increase the yield of the bio-oil and to make the bio-oil produced a beneficial addition to the field of bio-oil production parameter ...
Sunday Chukwuka Iweka, F.C. Ozioko, E.D. Edafiadhe, T.F. Adepoju   +3 more
doaj   +1 more source

Preparation, Characterization, and Evaluation of Breviscapine Nanosuspension and Its Freeze-Dried Powder

Pharmaceutics, 2022
As a biopharmaceutics classification system (BCS) class IV drug, breviscapine (Bre) has low solubility in water, poor chemical stability, a short biological half-life and rapid removal from plasma.
Ting Zhang, Xixi Li, Juewen Xu, Jingbao Shao, Meihong Ding, Senlin Shi   +5 more
doaj   +1 more source