Results 21 to 30 of about 12,374 (140)

Optimization of paclitaxel loaded poly (ε-caprolactone) nanoparticles using Box Behnken design

Beni-Suef University Journal of Basic and Applied Sciences, 2017
Optimization is a critical process in the development of nanoparticles to apprehend the formulation variables and quality attributes. The purpose of this study was to evaluate the influence of formulation variables viz., drug/polymer ratio (A ...
Nandhakumar Sathyamoorthy, Dhanaraju Magharla, Pavankumar Chintamaneni, Sundar Vankayalu   +3 more
doaj   +1 more source

Finite element model updating for the Tsing Ma Bridge tower based on surrogate models

Journal of Low Frequency Noise, Vibration and Active Control, 2022
This paper investigates the efficiency of three surrogate model-based dynamic finite element model updating methods, the response surface, the support vector regression, and the radial basis function neural network, using the engineering background of ...
Xiao-Xiang Cheng, Jian-Hua Fan, Zhi-Hong Xiao   +2 more
doaj   +1 more source

Bridging Virtual and Reality: Testing Design of Experiment Procedures with Simulated and Experimental Data

Engineering Proceedings, 2023
A virtual experiment conducted using the ICP-MS TuneSim software served as the basis for studies that compared the applicability of the central composite design with the Box–Behnken design in analytical chemistry applications.
Agnieszka Królicka, Anna Szczurkowska
doaj   +1 more source

USE OF BOX–BEHNKEN DESIGN FOR OPTIMIZATION OF COMPOUNDED MEDICATION: ACYCLOVIR CAPSULES REPORT

Drug Analytical Research, 2021
Campus compounding pharmacies play an important role in public health. Herpes simplex is one of the most common viral diseases in humans, which generates a great demand for acyclovir capsules in compounding pharmacy. It is well known that the formulation'
Suelen da Silva Reis, Valdemir da Silva Quintanilha Junior, Gabriella da Silva Boto, Thalita Martins da Silva, Elizabeth Valverde Macedo, Carlos Augusto de Freitas Peregrino , Samanta Cardozo Mourão, Emeli Moura de Araújo   +7 more
doaj   +5 more sources

Optimization And Characterization of Silver Nanoparticle Biosynthesis Using Parijoto Fruit (Medinilla speciosa) Water Extract With Box-Behnken Design

Journal of Food and Pharmaceutical Sciences
Silver nanoparticles in the medical field are used as additives in vaccines, anti-diabetic agents, wound and bone healing, biosensors and anticancer therapy in medical applications.
Qinta Laily Nurjana, Azizah Amin, Viviane Annisa, Siti Zahliyatul Munawiroh   +3 more
doaj   +1 more source

Optimization of the experimental parameters of fluticasone propionate microparticles for pulmonary delivery using a box behenken design

Journal of Pharmacy and Bioallied Sciences, 2012
The objective of this study was to examine extensively the influences of formulation and process variables on the microparticles. The microparticles were generated by the spray-drying technique using polymer chitosan, mannitol along with L-leucine.
P V Patel, T G Soni, V T Thakkar, T R Gandhi   +3 more
doaj   +1 more source

Optimization Studies on Imatinib Mesylate Loaded Nanoliposomes Using Box-Behnken Design

Nano Biomedicine and Engineering, 2022
Nanoliposomes are bilayer phospholipid vesicles used to encapsulate and deliver therapeutic agents. The study was aimed to investigate the effects of critical variables on nanoliposomes characteristics.
Mandeep Dahiya, Rajendra Awasthi, Gaurav Gupta, Sachin Kumar Singh, Monica Gulati, Niraj Kumar Jha, Saurabh Kumar Jha, Ankur Sharma, Parteek Prasher, Krishnan Anand, Dinesh Kumar Chellappan, Kamal Dua, Harish Dureja   +12 more
doaj   +1 more source

Design Optimization of Soft Fabric Pneumatic Actuators

Advanced Intelligent Systems, EarlyView.
This study presents a systematic optimization framework for elongating and bending fabric‐based soft pneumatic actuators. After a preliminary design‐space reduction, the framework minimizes energy consumption under mechanical performance constraints by integrating validated finite element modeling with statistical surrogate models. Optimal designs were
Grigorios M. Chatziathanasiou, Konstantina Tsintzira, Panagiotis Polygerinos   +2 more
wiley   +1 more source

Process Optimization of Solution Blow Spinning for Poly (N‐Isopropylacrylamide) Fibers

Journal of Applied Polymer Science, EarlyView.
Solution blow spinning has emerged as a safe and scalable technique for fabricating thermoresponsive PNIPAM fibers. The influence of key parameters on jet stability and fiber uniformity is determined through both rheological analysis and statistical process optimization. A Box–Behnken design reveals an optimized window for producing PNIPAM fibers below
Maryam Parastar, Filipe de Almeida Araujo, Uttandaraman Sundararaj   +2 more
wiley   +1 more source

Phosphorylation of Milkweed Fibers With a Phosphate Ester: Effect on Fiber Properties and Optimization of Reaction Conditions

Journal of Applied Polymer Science, EarlyView.
The phosphorylation of milkweed fibers using the phosphate ester/urea system was optimized. The impact of reaction temperature, duration, and phosphate ester ratio on the efficiency of phosphorylation was investigated using the design of experiments approach.
Ahmed Azrrar, François Brouillette, Zahahe Oulame Mouandhoime, Saïd Elkoun, Mathieu Robert   +4 more
wiley   +1 more source