Results 191 to 200 of about 10,233,222 (223)
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Optimization and development of antidiabetic phytosomes by the Box–Behnken design
Journal of Liposome Research, 2017Researchers have extensively reviewed on herbs and natural products for their marked clinical efficacy in some recent years, however, maximum of the newly discovered bioactive constituents offer poor bioavailability due to their large size molecules or to their poor miscibility with oils and lipids, thereby limiting their ability to pass across the ...
Sushila, Rathee, Anjoo, Kamboj
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Box-Behnken experimental design for the production of precipitated calcium carbonate
Pure and Applied Chemistry, 2016Abstract Calcium carbonate (CaCO3) was synthesized by means of ultrasonic process in the presence of the water-soluble polymer carboxymethyl inulin (CMI). Synthesized CaCO3 crystals were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), and BET (Brunauer, Emmett and Teller) isotherm.
Dogan, Ozlem +2 more
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Reinvestigating nanoprecipitation via Box–Behnken design: a systematic approach
Journal of Microencapsulation, 2014This work demonstrates Box-Behnken design (BBD)'s capability in exploring scientific principles governing a process, different from its use in process optimisation. We have investigated nanoprecipitation (NP) of temozolomide with polycaprolactone. Five factors, surfactant, stirring speed (SS), dropping rate (DR), phase-volume ratio (PVR) and drug ...
Yuvraj, Singh +3 more
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Formulation and optimization of rifampicin microparticles by Box-Behnken statistical design
Pharmaceutical Development and Technology, 2011The objective of the present study was to optimize and evaluate in vitro gastroretentive performance of rifampicin microparticles. Formulations were optimized using design of experiments by employing a 4-factor, 3-level Box-Behnken statistical design. Independent variables studied were the ratio of polymers (Eudragit RSPO: ethyl cellulose), inert drug ...
D P, Maurya +3 more
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Box–Behnken Designs and Their Applications in Pharmaceutical Product Development
2021Box–Behnken designs (BBDs) are the very efficient response surface design which provides information exclusively on the effect of experiment variables and overall experimental error in a minimum number of required runs. These designs possess very good symmetry and rotatability and also produce minimal experimental runs, as compared to the popular CCD ...
Sarwar Beg, Sohail Akhter
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Spherical Prediction-Variance Properties of Central Composite and Box-Behnken Designs
Technometrics, 1995For quadratic regression on the hypercube, a single-number criterion, such as a G efficiency that is based on the prediction variance, is often included as one of the criteria when selecting a response surface design, As an alternative to the single-number-criterion approach, the variance dispersion graph, presented by Giovannitti-Jensen and Myers, is ...
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Application of Box-Behnken design for treatment of tannery wastewater
2017Ministry of Education, Youth and Sports of the Czech Republic within the National Sustainability Programme [LO1303 (MSMT-7778/2014)]; European Regional Development Fund under the project CEBIA-Tech [CZ.1.05/2.1.00/03.0089]; Lac Hong University, Dongnai ...
Beltrán-Prieto, Juan Carlos +2 more
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