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Box–Behnken Designs and Their Applications in Pharmaceutical Product Development

2021
Box–Behnken designs (BBDs) are the very efficient response surface design which provides information exclusively on the effect of experiment variables and overall experimental error in a minimum number of required runs. These designs possess very good symmetry and rotatability and also produce minimal experimental runs, as compared to the popular CCD ...
Sarwar Beg, Sohail Akhter
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Optimisation for Photocatalytic Degradation of Malathion by Box–Behnken Design

Materials Today: Proceedings, 2018
Abstract Malathion is a pesticide that is generally utilized as a part of agriculture, private finishing, open amusement regions, and in general wellbeing nuisance control projects, for example, mosquito annihilation. In the US, it is the most ordinarily utilized organophosphate insecticide.
P.Neelima Reddi   +3 more
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Determination of Alendronate Sodium by Box-Behnken Statistical Design

Chromatographia, 2010
Spectrophotometric and LC methods have been developed and validated for the analysis of alendronate sodium in tablet dosage forms. Methods were based on reaction of the primary amino group of alendronate with ninhydrin reagent in methanolic solution of sodium bicarbonate.
Shaheen Sultana   +4 more
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Some new augmented fractional Box–Behnken designs

Communications in Statistics - Theory and Methods, 2016
ABSTRACTThe augmented Box–Behnken designs are used in the situations in which Box–Behnken designs (BBDs) could not estimate the response surface model due to the presence of third-order terms in the response surface models. These designs are too large for experimental use.
Fareeha Rashid   +3 more
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A note on the robustness of Box-Behnken designs to the unavailability of data

Metrika, 1998
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Microbiological improvement of soils with Box–Behnken experimental design

Acta Geophysica
Karadeniz Teknik niversitesi [FDK-2022-10406]; Scientific Research Projects Coordination Unit of Karadeniz Technical University -- We would like to express our gratitude to the Scientific Research Projects Coordination Unit of Karadeniz Technical University, which provided the funding for this study (Project ID: FDK-2022-10406/Determination of ...
Zehra Ertosun Karabulut   +2 more
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Sorption studies of strontium on carbon nanotubes using the Box–Behnken design

Radiochimica Acta, 2014
Abstract Adsorption of Sr on multi-walled carbon nanotubes (MWCNTs) was investigated to explore their possible use as an efficient adsorbent for nuclear waste streams. MWCNTs were purified and oxidized with HNO3 prior to testing adsorption.
Aslani, Ceren Kutahyali   +3 more
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Application of response surface methodology with a Box–Behnken design for struvite precipitation

Advanced Powder Technology, 2019
Abstract Struvite crystals were precipitated by the reaction of magnesium chloride hexahydrate and ammonium dihydrogen phosphate using different concentrations of citric acid as the additive (100, 300, and 500 ppm). The structure, morphology, functional groups and particle size of the crystals were evaluated experimentally by scanning electron ...
Sevgi Polat, Perviz Sayan
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Optimization of valsartan encapsulation in biodegradables polyesters using Box-Behnken design

Materials Science and Engineering: C, 2018
The aim of this study was to encapsulate an antihypertensive drug (valsartan) within polyester microparticles, namely constituted of poly (lactic acid) (PLA) and poly (ε-caprolactone) (PCL), by using the emulsion solvent evaporation method. In order to optimize the parameters of valsartan encapsulation, design of experiments was applied.
Ounissa, Sadoun   +2 more
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