Results 71 to 80 of about 13,345 (178)

Design, development and optimization of gastro-retentive floating in-situ gels loaded with carvedilol microspheres using response surface methodology

Acta Marisiensis - Seria Medica
Aim: The goal of this study was to formulate and optimize gastro-retentive floating in-situ gel comprising optimized microspheres by Box-Behnken design.
Kukati Latha, Rahman Aisha, Fatima Aymen, Menon Vyshak R, Lakshmi SVVNSM   +4 more
doaj   +1 more source

Development and Validation of Two Analytical Methods Using High‐Performance Liquid Chromatography and Atomic Absorption Spectroscopy for the Analysis of Tunisian Marketed Pharmaceutical Product‐Based Insulin and Zinc: Application in Routine Stability Study

Biomedical Chromatography, Volume 40, Issue 11, November 2026.
ABSTRACT Given the widespread reliance on insulin among diabetic patients, ensuring its stability is an essential task not only for preserving its therapeutic efficacy but also for safeguarding patient health and safety. In addition, insulin storage practices were frequently misunderstood that may compromise drug potency.
Majdi Ben Messaoud, Sarra Mahfoudhi, Dorra Amor, Yassine Mokni, Kaouther Louati, Kaouther Zribi, Asma Omezzine, Fathi Safta   +7 more
wiley   +1 more source

Isolation, Structural Elucidation, and Anti‐Melanogenic Activity of a Novel Pectic Polysaccharide From Alhagi camelorum Fisch

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
Polysaccharide extraction from Alhagi camelorum Fisch. was optimized, yielding ACP‐II‐1, a novel GalA‐rich, HG‐dominant pectin (26.145 kDa) containing branched RG‐I domains. ACP‐II‐1 reduced melanogenesis in forskolin‐stimulated B16F10 cells and a zebrafish model.
Zhitao Liu, Shuyan Han, Nannan Xu, Nuermaimaiti Abudukelimu, Jiangyu Zhao   +4 more
wiley   +1 more source

Box–Behnken optimization and ANN‐ANFIS integrated modelling for transesterification using thermally activated basic oxygen furnace slag catalyst

The Canadian Journal of Chemical Engineering, Volume 104, Issue 11, Page 5991-6006, November 2026.
Abstract Global energy demand and environmental concerns have intensified the search for renewable and sustainable energy sources. This study thus, focuses on optimizing the transesterification process of waste cooking oil (WCO) using thermally activated basic oxygen furnace slag catalyst calcined at 850°C (BOF 850). The optimization and modelling were
Johra S. Ali, Hillary L. Rutto
wiley   +1 more source

Development, Optimization, and Physicochemical Characterization of Fluorescent Carbon Dot‐Ginkgo biloba Extract Co‐Loaded Niosomes for Future Neurological Disease‐Relevant Evaluation

CNS Neuroscience &Therapeutics, Volume 32, Issue 11, November 2026.
Carbon dot–Ginkgo biloba–loaded niosomal nanovesicles are fabricated via rotary evaporation, probe sonication, and centrifugation to co‐deliver natural neuroprotective agents to the brain. The optimized system shows high encapsulation, sustained release, and excellent biocompatibility, suggesting a promising nano‐vesicular platform for Alzheimer's ...
Yasaman Mohammadi, Mohammad Saied Salehi, Ehsan Heidari, Mina Ebrahimi, Nahid Ashjazadeh   +4 more
wiley   +1 more source

Comparative Analysis of Traditional and Modern Extraction Techniques for Phenolic Compounds From Leontopodium and Optimization of Extraction Process Using Response Surface Methodology

Food Science &Nutrition, Volume 14, Issue 11, November 2026.
Ultrasonic‐assisted extraction was identified as the most effective method for recovering TFC and TPC from LLB, with response surface analysis used to optimize the extraction conditions. The desert grassland sample had the highest TFC content (46.15 mg/g) and the strongest antioxidant activity.
Rule Yi, Junfeng Hao, Jian Bao, Muqier Zhao, Zhijun Wang, Zhuna Bao, Gentu Ge   +6 more
wiley   +1 more source

Curcumin in the Treatment of Various Diseases: Mechanism of Action, Bioavailability, Therapeutic Effects, and Current Clinical Trials

MedComm, Volume 7, Issue 11, November 2026.
Curcumin, a naturally occurring polyphenol, exhibits significant anti‐inflammatory and antioxidant capabilities. This review elucidates the specific molecular mechanisms by which curcumin exerts therapeutic effects on various diseases, including neurological disorders, cardiovascular diseases, cancers, inflammatory disorders, and autoimmune diseases ...
Lin Wang, Qifei Pan, Wenjuan Long, Xinyao Li, Jianqin Mao, Sitong Zhou, Zihui Wang, Xuelian Zou, Yuqing She, Mingqin Shi, Yang Zhou, Jiarong Du, Zhongyang Hu, Xiaoman Lv, Yishu Chen, Dongdong Qin   +15 more
wiley   +1 more source

Sustainable Pb (II) Removal via Pine‐Bark Biochar Valorization: Removal Mechanisms and Response‐Surface Modeling

Water Environment Research, Volume 98, Issue 11, November 2026.
PB5 biochar derived from pine bark achieved 91.43% Pb (II) removal under optimized conditions. Efficient Pb (II) sequestration was governed by carbonate‐induced surface precipitation of cerussite (PbCO3) and subsequent pore filling. ABSTRACT Lead (Pb (II)) is a persistent contaminant in industrial wastewater. This study evaluated pine bark (PB)‐derived
Eun‐Chae Im, Jae‐In Lee, Seong‐Jik Park, Chang‐Gu Lee   +3 more
wiley   +1 more source

Cereal Biomass Valorization for Functional Food Ingredients: Fractionation and Circular Biorefinery Strategies

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 6, November 2026.
ABSTRACT Food processing must transition toward resource‐efficient systems that operate within planetary boundaries. Cereals, as climate‐resilient staples, offer strong potential to valorize nutrient‐rich fractions. Zero‐waste biorefinery concepts and green fractionation technologies, integrated with structure–function principles, enable the conversion
Rahul Biswas, Marjo Pöysä, Samson Adeoye Oyeyinka, Abayneh Getachew Demesa, Savindi Wanninayake, Samuel Perez‐Vega   +5 more
wiley   +1 more source

Synbiotic Kefir‐Yacon Drink Ameliorates Hypertension by Modulating Antioxidant and Anti‐Inflammatory Pathways

Journal of Food Science, Volume 91, Issue 11, November 2026.
ABSTRACT Hypertension is associated with oxidative stress, chronic inflammation, and gut microbiota dysbiosis. This study evaluated whether a fermented kefir‐yacon synbiotic beverage could improve hemodynamic parameters in a hypertension model through its antioxidant, anti‐inflammatory, and gut microbiota‐modulating effects.
Flavia de Souza Andrade Moraes, Maressa de Carvalho Fragoso, Cristiane Lyrio da Silva, Karynna Alcantara Dutra, Lucas Gueller da Silva Gonçalves, Lucas Andrade Campelo, Antonio Ferreira de Melo Junior, Nazare Souza Bissoli, Girlandia Alexandre Brasil Amorim, Ewelyne Miranda de Lima, Tadeu Uggere de Andrade   +10 more
wiley   +1 more source