Results 51 to 60 of about 37,111 (284)

Formulation and characterization of ketoprofen liquisolid compacts by Box-Behnken design

International Journal of Pharmaceutical Investigation, 2012
Liquisolid technique is used in delivery of lipophilic and poorly water soluble drugs through oral route. It involves dissolving water insoluble drugs in nonvolatile solvents and converting into acceptably flowing and compressible powders. The objective of the present work was to enhance the dissolution rate of ketoprofen using microcrystalline ...
Vittal, G Vijayaranga, Deveswaran, R, Bharath, S, Basavaraj, BV, Madhavan, V   +4 more
openaire   +3 more sources

Optimization of Reaction Conditions in the Production of Gadolinium Diethylenetriamine Pentaacetate-Folate [PDF]

, 2015
A previous study has performed the laboratory-scale synthesis and characterization of Gadolinium Diethylenetriaminepentaacetate-Folate. Some parameters associated with the synthesis have been defined.
Anggraeni, A., Fauzia, R. P., Gunawan, A. H., Mutalib, A.   +3 more
core  

Using Box–Behnken experimental design to optimize the degradation of Basic Blue 41 dye by Fenton reaction

, 2020
Degradation of a Basic Blue 41 dye using Fenton reagent was examined at laboratory scale in batch experiments using Box-Behnken statistical experiment design.
Kiflie, Zebene, Solomon, Desta, Van Hulle, Stijn   +2 more
core   +2 more sources

Ionic behavior assessment of surface-active compounds from corn steep liquor by exchange resins [PDF]

, 2016
Depending on their ionic nature, biosurfactants can be classified as nonionic, anionic, cationic, or amphoteric. The ionic behavior of biosurfactants is an important characteristic that dictates their use in industrial applications.
Cruz, J. M., Moldes, A., Rincón Fontán, M., Rodriguez López, L., Vecino Bello, Xanel   +4 more
core   +2 more sources

A Rational Optimization Approach for the Development of a Multiplexed Lateral Flow Immunoassay: Detection of Nonepithelial Ovarian Cancer Markers in Human Serum

Advanced Science, EarlyView.
This study outlines the developmental pipeline of a multiplexed nanozyme‐based lateral flow immunoassay for the purpose of ovarian germ cell tumor detection. It demonstrates the application of a design of experiments optimization approach for nanozyme probe conjugate development.
Aida Abdelwahed, Carl E. Eskildsen, Luca Panariello, André Shamsabadi, Christy J. Sadler, Edmund H. Wilkes, Federico Galvanin, Yuxi Cheng, Sara Carvalho, Srdjan Saso, Molly M. Stevens   +10 more
wiley   +1 more source

Advanced Experiment Design Strategies for Drug Development

Advanced Intelligent Discovery, EarlyView.
Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang, Anthony Harker, Mohan Edirisinghe, Maryam Parhizkar   +3 more
wiley   +1 more source

Optimization of bioethanol production from simultaneous saccharification and fermentation of pineapple peels using Saccharomyces cerevisiae

Journal of Applied Sciences and Environmental Management, 2018
In this study, bioethanol production from the simultaneous saccharification and fermentation (SSF) of pineapple peels using cellulase and Saccharomyces cerevisiae was investigated. A three-factor Box-behnken design (BBD) and response surface methodology
O Oiwoh, B.V. Ayodele, N.A. Amenaghawon, C.O. Okieimen   +3 more
doaj   +3 more sources

Preparation of superhydrophobic nanocalcite crystals using Box–Behnken design

Arabian Journal of Chemistry, 2019
AbstractSuperhydrophobic nanocalcite crystals were prepared via an adjusted aqueous reaction of CaO, CO2 gas and sodium oleate. Box–Behnken design was used to optimize the preparation parameters such as CaO concentration, CO2 gas flow rate and surfactant concentration. The results revealed that the produced CaCO3 is indexed to the calcite phase.
Barhoum, Ahmed, M. El-Sheikh, Said, El-Sherbiny, Samya, A. Morsy, Fatma, Abdel-Hamid El-Midany, Ayman, Rahier, Hubert   +5 more
openaire   +2 more sources

Autonomous AI‐Driven Design for Skin Product Formulations

Advanced Intelligent Discovery, EarlyView.
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang, Yongrui Xiao, Chunlin Chen, Dimitrios Tsaoulidis, Kai Yang, Tao Chen   +5 more
wiley   +1 more source

Optimization of Physical and Cultural Conditions of Fibrinolytic Enzyme from Bacillus altitudinis S-CSR 0020

Journal of Pure and Applied Microbiology, 2018
The main aim of this work was optimization of physical conditions as well as medium components for the maximum production of fibrinolytic enzyme. A fibrinolytic enzyme producing organism was isolated from soil and identified as Bacillus altitudinis ...
K.V. Smitha, B.V. Pradeep
doaj   +1 more source