Results 51 to 60 of about 194,582 (273)
Optimization Studies on Imatinib Mesylate Loaded Nanoliposomes Using Box-Behnken Design
Nanoliposomes are bilayer phospholipid vesicles used to encapsulate and deliver therapeutic agents. The study was aimed to investigate the effects of critical variables on nanoliposomes characteristics.
Mandeep Dahiya +12 more
doaj +1 more source
Herbal raw materials with antidiabetic activity can be a valuable support to therapy. An optimized extraction process allows for the best possible health-promoting effect.
Anna Gościniak +3 more
semanticscholar +1 more source
Preparation of superhydrophobic nanocalcite crystals using Box–Behnken design
AbstractSuperhydrophobic nanocalcite crystals were prepared via an adjusted aqueous reaction of CaO, CO2 gas and sodium oleate. Box–Behnken design was used to optimize the preparation parameters such as CaO concentration, CO2 gas flow rate and surfactant concentration. The results revealed that the produced CaCO3 is indexed to the calcite phase.
Barhoum, Ahmed +5 more
openaire +2 more sources
Advanced Experiment Design Strategies for Drug Development
Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang +3 more
wiley +1 more source
Rheological and Mechanical Analyses of Felbinac Cataplasms by Using Box–Behnken Design
Felbinac, an active pharmaceutical ingredient (API) used clinically for the treatment of osteoarthritis, has poor solubility. Felbinac cataplasm product design was investigated using rheological and mechanical analyses.
Jie Yang +3 more
doaj +1 more source
Autonomous AI‐Driven Design for Skin Product Formulations
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang +5 more
wiley +1 more source
Box-Behnken design experiments and results.
Box-Behnken design experiments and results.
Xingchu Gong (611198) +3 more
core +1 more source
Box-Behnken design and experimental values of induced airflow velocity (Y1) and dust concentration (Y2).
Qingjie Qi (9674147) +3 more
core +1 more source
The present work deals with QbD-based development of FEB-loaded nanoemulsion (FEB-NE) in order to enhance bioavailability and permeability. In the beginning, the risk assessment was performed on different experimental variables using the Ishikawa diagram
Vishal C. Gurumukhi +5 more
doaj +1 more source
Formulation and characterization of ketoprofen liquisolid compacts by Box-Behnken design
Liquisolid technique is used in delivery of lipophilic and poorly water soluble drugs through oral route. It involves dissolving water insoluble drugs in nonvolatile solvents and converting into acceptably flowing and compressible powders. The objective of the present work was to enhance the dissolution rate of ketoprofen using microcrystalline ...
Vittal, G Vijayaranga +4 more
openaire +3 more sources

