Results 51 to 60 of about 194,582 (273)

Optimization Studies on Imatinib Mesylate Loaded Nanoliposomes Using Box-Behnken Design

open access: yesNano Biomedicine and Engineering, 2022
Nanoliposomes are bilayer phospholipid vesicles used to encapsulate and deliver therapeutic agents. The study was aimed to investigate the effects of critical variables on nanoliposomes characteristics.
Mandeep Dahiya   +12 more
doaj   +1 more source

Pomegranate Flower Extract—The Health-Promoting Properties Optimized by Application of the Box–Behnken Design

open access: yesMolecules, 2022
Herbal raw materials with antidiabetic activity can be a valuable support to therapy. An optimized extraction process allows for the best possible health-promoting effect.
Anna Gościniak   +3 more
semanticscholar   +1 more source

Preparation of superhydrophobic nanocalcite crystals using Box–Behnken design

open access: yesArabian Journal of Chemistry, 2019
AbstractSuperhydrophobic nanocalcite crystals were prepared via an adjusted aqueous reaction of CaO, CO2 gas and sodium oleate. Box–Behnken design was used to optimize the preparation parameters such as CaO concentration, CO2 gas flow rate and surfactant concentration. The results revealed that the produced CaCO3 is indexed to the calcite phase.
Barhoum, Ahmed   +5 more
openaire   +2 more sources

Advanced Experiment Design Strategies for Drug Development

open access: yesAdvanced Intelligent Discovery, EarlyView.
Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang   +3 more
wiley   +1 more source

Rheological and Mechanical Analyses of Felbinac Cataplasms by Using Box–Behnken Design

open access: yesPharmaceutics, 2018
Felbinac, an active pharmaceutical ingredient (API) used clinically for the treatment of osteoarthritis, has poor solubility. Felbinac cataplasm product design was investigated using rheological and mechanical analyses.
Jie Yang   +3 more
doaj   +1 more source

Autonomous AI‐Driven Design for Skin Product Formulations

open access: yesAdvanced Intelligent Discovery, EarlyView.
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang   +5 more
wiley   +1 more source

Box-Behnken design experiments and results.

open access: yes, 2014
Box-Behnken design experiments and results.
Xingchu Gong (611198)   +3 more
core   +1 more source

Box-Behnken design and experimental values of induced airflow velocity (Y1) and dust concentration (Y2).

open access: yes, 2022
Box-Behnken design and experimental values of induced airflow velocity (Y1) and dust concentration (Y2).
Qingjie Qi (9674147)   +3 more
core   +1 more source

Quality-by-design based fabrication of febuxostat-loaded nanoemulsion: Statistical optimization, characterizations, permeability, and bioavailability studies

open access: yesHeliyon, 2023
The present work deals with QbD-based development of FEB-loaded nanoemulsion (FEB-NE) in order to enhance bioavailability and permeability. In the beginning, the risk assessment was performed on different experimental variables using the Ishikawa diagram
Vishal C. Gurumukhi   +5 more
doaj   +1 more source

Formulation and characterization of ketoprofen liquisolid compacts by Box-Behnken design

open access: yesInternational Journal of Pharmaceutical Investigation, 2012
Liquisolid technique is used in delivery of lipophilic and poorly water soluble drugs through oral route. It involves dissolving water insoluble drugs in nonvolatile solvents and converting into acceptably flowing and compressible powders. The objective of the present work was to enhance the dissolution rate of ketoprofen using microcrystalline ...
Vittal, G Vijayaranga   +4 more
openaire   +3 more sources

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