Results 81 to 90 of about 153,301 (238)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Effects of Scale Parameters and Counting Origins on Box-Counting Fractal Dimension and Engineering Application in Concrete Beam Crack Analysis

Fractal and Fractional
Fractal theory provides a powerful tool for quantifying complex geometric patterns such as concrete cracks. The box-counting method is widely employed for fractal dimension (FD) calculation due to its intuitive principles and compatibility with image ...
Junfeng Wang, Gan Yang, Yangguang Yuan, Jianpeng Sun, Guangning Pu   +4 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Box-Counting Dimension in One-Dimensional Random Geometry of Multiplicative Cascades. [PDF]

Commun Math Phys, 2023
Falconer KJ, Troscheit S.
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

FRACTAL DIMENSION AND LACUNARITY COMBINATION FOR PLANT LEAF CLASSIFICATION

Jurnal Ilmu Komputer dan Informasi, 2016
Plants play important roles for the existence of all beings in the world. High diversity of plant’s species make a manual observation of plants classifying becomes very difficult. Fractal dimension is widely known feature descriptor for shape or texture.
Mutmainnah Muchtar, Nanik Suciati, Chastine Fatichah   +2 more
doaj   +1 more source

A spatial randomness test based on the box-counting dimension. [PDF]

Adv Stat Anal, 2022
Caballero Y, Giraldo R, Mateu J.
europepmc   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Problems of the Grid Size Selection in Differential Box-Counting (DBC) Methods and an Improvement Strategy. [PDF]

Entropy (Basel), 2022
Jiang W, Liu Y, Wang J, Li R, Liu X, Zhang J.   +5 more
europepmc   +1 more source

Accuracy analysis of the box-counting algorithm

, 2011
Accuracy of the box-counting algorithm for numerical computation of the fractal exponents is investigated. To this end several sample mathematical fractal sets are analyzed.
Drozdz, S., Gorski, A. Z., Mokrzycka, A., Pawlik, J.   +3 more
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