Results 61 to 70 of about 21,052 (223)

Formulation and characterization of ketoprofen liquisolid compacts by Box-Behnken design

open access: yesInternational Journal of Pharmaceutical Investigation, 2012
Liquisolid technique is used in delivery of lipophilic and poorly water soluble drugs through oral route. It involves dissolving water insoluble drugs in nonvolatile solvents and converting into acceptably flowing and compressible powders. The objective of the present work was to enhance the dissolution rate of ketoprofen using microcrystalline ...
Vittal, G Vijayaranga   +4 more
openaire   +3 more sources

Box–Behnken Design for Polycarbonate-Pigment Blending: Applications and Characterization Techniques

open access: yesPolymers, 2022
Incorporating pigments into polymers can be done for various purposes, including the introduction of color, interfacial effects, or aesthetics. If these pigments are to disperse properly, then the process of extrusion must be optimized. During polymer compounding extrusion, three effective processing factors were investigated: feed rate (FR), speed (Sp.
Jamal Alsadi   +9 more
openaire   +2 more sources

Design Optimization of Soft Fabric Pneumatic Actuators

open access: yesAdvanced Intelligent Systems, EarlyView.
This study presents a systematic optimization framework for elongating and bending fabric‐based soft pneumatic actuators. After a preliminary design‐space reduction, the framework minimizes energy consumption under mechanical performance constraints by integrating validated finite element modeling with statistical surrogate models. Optimal designs were
Grigorios M. Chatziathanasiou   +2 more
wiley   +1 more source

Sustainable levulinic acid production from inulin via hydrothermal conversion

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract This study investigates the hydrothermal conversion of inulin using potassium pyrosulfate to levulinic acid (LA). The Box–Behnken design approach was applied to optimize the conversion parameters and analyze the interactions influencing LA yield.
Gwi‐Taek Jeong
wiley   +1 more source

Factors for the response surface Box-Behnken design. [PDF]

open access: yes, 2016
Temperature, E/S ratio, pH, and hydrolysis time at three levels for the response surface Box-Behnken design. (DOCX)
Zhaoxia Wang (470659)   +6 more
core   +1 more source

Dynamic, Unconstrained Optimization of Secreted Enzyme Production in Fed‐Batch Fermentation Using Reinforcement Learning

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Reinforcement learning (RL) has been used to control a wide range of dynamic processes, especially ones that are too complex to model well or have stochastic environmental perturbations. Fed‐batch fermentations are subject to changes in starting cell growth rates and process variations that can affect cell growth and secreted target production.
Sai Harish Uthravalli   +3 more
wiley   +1 more source

Optimization of Physical and Cultural Conditions of Fibrinolytic Enzyme from Bacillus altitudinis S-CSR 0020

open access: yesJournal of Pure and Applied Microbiology, 2018
The main aim of this work was optimization of physical conditions as well as medium components for the maximum production of fibrinolytic enzyme. A fibrinolytic enzyme producing organism was isolated from soil and identified as Bacillus altitudinis ...
K.V. Smitha, B.V. Pradeep
doaj   +1 more source

Eudragit®‐engineered pH‐responsive probiotic microspheres with enhanced gastrointestinal resistance and prolonged storage stability for inflammatory bowel disease therapy

open access: yesBMEMat, EarlyView.
This study reports the development of AMS@Eud core‐shell microspheres, combining calcium alginate and pH‐responsive Eudragit® L100, which exhibit exceptional gastrointestinal resistance and long‐term storage stability (only 5.28%–9.09% viability loss over 35 days at 4–25°C), and effectively alleviate inflammatory bowel disease via gut microbiota ...
Ming Teng   +5 more
wiley   +1 more source

Optimization of bioethanol production from simultaneous saccharification and fermentation of pineapple peels using Saccharomyces cerevisiae

open access: yesJournal of Applied Sciences and Environmental Management, 2018
In this study, bioethanol production from the simultaneous saccharification and fermentation (SSF) of pineapple peels using cellulase and Saccharomyces cerevisiae was investigated. A three-factor Box-behnken design (BBD) and response surface methodology
O Oiwoh   +3 more
doaj   +3 more sources

Optimization of Combined Pre-Treatment Process for Bleaching of Cotton Woven Fabric Using Box–Behnken Design

open access: yesJournal of Natural Fibers
The conventional bleaching process for cotton woven fabrics is characterized by high consumption of chemicals, water, and energy, resulting in significant environmental impact through elevated energy use and wastewater discharge.
Bantamlak Birlie Kassie   +2 more
doaj   +1 more source

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