Results 41 to 50 of about 135,666 (260)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier +11 more
wiley +1 more source
Frontiers in Forests and Global Change, 2022 The adaptation of forest management to changing environmental conditions due to climate change relies on information on the current forest and tree vitality. In common practice, the percentage of crown defoliation is used as a proxy for tree vitality, an
Marius G. Heidenreich, Dominik Seidel
doaj +1 more source
Hyperbolic graphs: Critical regularity and box dimension
Transactions of the American Mathematical Society, 2019 We study fractal properties of invariant graphs of hyperbolic and partially hyperbolic skew product diffeomorphisms in dimension three. We describe the critical (either Lipschitz or at all scales Hölder continuous) regularity of such graphs. We provide a formula for their box dimension given in terms of appropriate pressure functions.
Díaz, Lorenzo Justiniano +3 more
openaire +3 more sources
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
On sets containing a unit distance in every direction
Discrete Analysis, 2021 On sets containing a unit distance in every direction, Discrete Analysis 2021:5, 13 pp. A _Kakeya set_ in $\mathbb R^d$ is a subset $A\subset\mathbb R^d$ that contains a line in every direction. Besicovitch famously proved that a Kakeya set in $\mathbb
Pablo Shmerkin, Han Yu
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Relative multifractal box-dimensions
Filomat, 2019 Given two probability measures ? and ? on Rn. We define the upper and lower relative multifractal box-dimensions of the measure ? with respect to the measure ? and investigate the relationship between the multifractal box-dimensions and the relative multifractal Hausdorff dimension, the relative multifractal pre-packing dimension.
Attia, Najmeddine, Selmi, Bilel
openaire +3 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Ecology and Evolution, 2018 The three‐dimensional forest structure affects many ecosystem functions and services provided by forests. As forests are made of trees it seems reasonable to approach their structure by investigating individual tree structure.
Dominik Seidel
doaj +1 more source