Results 61 to 70 of about 1,003,949 (307)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Drivers of Forest Structural Complexity in Mountain Forests of Nepal

open access: yesMountain Research and Development
Forests in the Himalayan region are crucial for maintaining the region's ecological balance, conserving biodiversity, and supporting the livelihoods of local people.
Prakash Basnet   +4 more
doaj   +1 more source

Device-independent tests of classical and quantum dimensions

open access: yes, 2010
We address the problem of testing the dimensionality of classical and quantum systems in a `black-box' scenario. We develop a general formalism for tackling this problem.
A. S. Holevo   +4 more
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

What is the variant of fractal dimension under addition of functions with same dimension and related discussions

open access: yesAIMS Mathematics
This paper attempts to explore possible box dimension of two added fractal continuous functions with the same dimension. Two interesting and meaningful results are obtained.
Ruhua Zhang , Wei Xiao
doaj   +1 more source

Some boundary effects in quantum field theory

open access: yes, 2004
We have constructed a quantum field theory in a finite box, with periodic boundary conditions, using the hypothesis that particles living in a finite box are created and/or annihilated by the creation and/or annihilation operators, respectively, of a ...
E. H. Lieb   +8 more
core   +2 more sources

Box Dimension and Cyclicity of Canard Cycles [PDF]

open access: yesQualitative Theory of Dynamical Systems, 2017
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Fractional differentiability of nowhere differentiable functions and dimensions

open access: yes, 1996
Weierstrass's everywhere continuous but nowhere differentiable function is shown to be locally continuously fractionally differentiable everywhere for all orders below the `critical order' 2-s and not so for orders between 2-s and 1, where s ...
Abott L. F.   +19 more
core   +3 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

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