Results 61 to 70 of about 957,336 (307)
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Device-independent tests of classical and quantum dimensions
We address the problem of testing the dimensionality of classical and quantum systems in a `black-box' scenario. We develop a general formalism for tackling this problem.
A. S. Holevo+4 more
core +1 more source
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke+2 more
wiley +1 more source
Robustness of Device Independent Dimension Witnesses
Device independent dimension witnesses provide a lower bound on the dimensionality of classical and quantum systems in a "black box" scenario where only correlations between preparations, measurements and outcomes are considered.
Antonio Acín+5 more
core +1 more source
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
Some boundary effects in quantum field theory
We have constructed a quantum field theory in a finite box, with periodic boundary conditions, using the hypothesis that particles living in a finite box are created and/or annihilated by the creation and/or annihilation operators, respectively, of a ...
E. H. Lieb+8 more
core +2 more sources
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt+8 more
wiley +1 more source
Drivers of Forest Structural Complexity in Mountain Forests of Nepal
Forests in the Himalayan region are crucial for maintaining the region's ecological balance, conserving biodiversity, and supporting the livelihoods of local people.
Prakash Basnet+4 more
doaj +1 more source
Design of a Biaxial Laminar Shear Box for 1g Shaking Table Tests
In this paper, the design of a new laminar shear box at the Laboratory of Earthquake Engineering and Dynamic Analysis (L.E.D.A.) of the University of Enna “Kore” (Sicily, Italy), is presented.
Francesco Castelli+3 more
doaj +1 more source