Results 101 to 110 of about 2,896,241 (272)

Analyzing noninferiority trials: it is time for advantage deficit assessment – an observational study of published noninferiority trials

Open Access Journal of Clinical Trials, 2015
Beryl Primrose Gladstone, Werner Vach Clinical Epidemiology Group, Center for Medical Biometry and Medical Informatics, Medical Center, University of Freiburg, Freiburg, Germany Abstract: The concept of noninferiority (NI) trials is based on a belief ...
Gladstone BP, Vach W
doaj  

Unattended versus two attended, ambulatory and central blood pressure measurements in hypertensive patients with and without diabetes

Blood Pressure, 2019
Objective: To compare unattended blood pressure (BP) with two attended BP, with 24-h ambulatory (ABPM) and central BP measurements in hypertensive patients with (DMs) and without diabetes (HTs).
Jorge Polonia, Cristina Baptista, Jose Silva, Loide Barbosa   +3 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Positive linear functionals on BP*-algebras [PDF]

, 2015
Let A be a BP*-algebra with identity e, P_{1}(A) be the set of all positive linear functionals f on A such that f(e) = 1, and let M_{s}(A) be the set of all nonzero hermitian multiplicative linear functionals on A.
Azhari, M. El
core  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Optimal delivery of follow-up care after surgery for Crohn’s disease: current perspectives

Clinical and Experimental Gastroenterology, 2016
James P Campbell, Byron P Vaughn Department of Gastroenterology, Hepatology and Nutrition, University of Minnesota, Minneapolis, MN, USA Abstract: Despite improvements in medical therapies for Crohn’s disease (CD), up to 70% of patients ...
Campbell JP, Vaughn BP
doaj  

Complete genome sequence of the Medicago microsymbiont Ensifer (Sinorhizobium) medicae strain WSM419 [PDF]

, 2010
Ensifer (Sinorhizobium) medicae is an effective nitrogen fixing microsymbiont of a diverse range of annual Medicago (medic) species. Strain WSM419 is an aerobic, motile, non-spore forming, Gram-negative rod isolated from a M.
Ardley, J.K., Bräu, L., Chain, P., Chang, Y-J, Copeland, A., Dilworth, M.J., Gollagher, M., Hauser, L., Howieson, J.G., Ivanova, N., Kiss, H., Kyrpides, N, Land, M., Lapidus, A., Malfatti, S., Markowitz, V., Mavromatis, K., Nandasena, K.G., Nolan, M., O'Hara, G.W., Reeve, W.G., Tiwari, R., Yates, R.J.   +22 more
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Effect of Difference Tropical Fibrous Feeds on Feed Intake and Digestibility in Swamps Buffaloes Compared to Ongole Cattle

Animal Production: Indonesian Journal of Animal Production, 2010
This research was aimed to examine the effect of difference fibrous feeds on feed intake and digestibility in swamps buffaloes compared to ongoles cattles. Twelve ongole and twelve buffaloes were used in in vivo digestibility. Ten feeds were used in this
BP Widyobroto, SPS Budhi
doaj