Results 81 to 90 of about 2,896,241 (272)

Genetic characterization of citrus rootstocks by using STMS markers : [P24] [PDF]

, 2008
STMS markers were used to characterize 41 Citrus rootstocks: A total of 10 Citrus-specific primers were tested, and 9 produced clear, reproducible and discrete bands.
Gonul, S., Incesu, M., Kacar, A.Yildiz, Kamiloglu, M.U., Ollitrault, Patrick, Tuzcu, O., Yesiloglu, Turgut, Yildirim, B.   +7 more
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

An observational study of pharmacological interventions in complicated pregnancies in a tertiary care hospital

National Journal of Physiology, Pharmacy and Pharmacology, 2016
Background: Pregnancy care is one of the greatest challenges in medicine and it demands a special care in the use of drugs because of altered physiology.
Sri Vidya BP, Nagabushan H
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Community-based education in the Institute of Medicine, Tribhuvan University, Nepal: a qualitative assessment

Advances in Medical Education and Practice, 2019
Bishnu P ChoulagaiDepartment of Community Medicine and Public Health, Institute of Medicine, Tribhuvan University, Kathmandu, NepalBackground: Community-based education (CBE) involves learning activities that take place in a community setting.
Choulagai BP
doaj  

An analytic virtual-source-based current-voltage model for ultra-thin black phosphorus field-effect transistors

, 2018
In this paper, we develop an analytic physics-based model to describe current conduction in ultra-thin black phosphorus (BP) field-effect transistors (FETs). The model extends the concept of virtual source charge calculation to capture the effect of both
Haratipour, Nazila, Koester, Steven J., Rakheja, Shaloo, Yarmoghaddam, Elahe   +3 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Simulation for business processes and information systems design [PDF]

, 2003
Business Process (BP) literature promotes the value of business processes as essential gearwheels that help organizations to reach their goals. Similarly, many process design approaches claim that Information Technology (IT) is a major enabler of ...
Paul, RJ, Serrano, A
core  

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source