C-253 INNOVACIÓN E INVESTIGACIÓN, IMPRESCINDIBLES PARA EL DESARROLLO DE LAS NACIONES
C-253 INNOVACIÓN E INVESTIGACIÓN, IMPRESCINDIBLES PARA EL DESARROLLO DE LAS NACIONESC-253 INNOVACIÓN E INVESTIGACIÓN, IMPRESCINDIBLES PARA EL DESARROLLO DE LAS ...
Coordinación de Comunicación Social, Imágenes
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Identification, validation, and characterization of approved and investigational drugs interfering with the SARS-CoV-2 endoribonuclease Nsp15. [PDF]
Abstract Since the emergence of SARS‐CoV‐2 at the end of 2019, the virus has caused significant global health and economic disruptions. Despite the rapid development of antiviral vaccines and some approved treatments such as remdesivir and paxlovid, effective antiviral pharmacological treatments for COVID‐19 patients remain limited. This study explores
Chatziefthymiou SD +13 more
europepmc +2 more sources
Nucleic Acid Therapeutics for "Undruggable" Cancer Targets: Mechanisms, Challenges, and Prospects. [PDF]
Nucleic acid therapeutics bypass the structural limitations of conventional drugs by targeting mRNA rather than proteins. This review examines how antisense oligonucleotides, siRNAs, miRNAs, aptamers, and mRNA vaccines intervene against historically undruggable oncoproteins including Ras, MYC, and p53, highlighting mechanistic advances, delivery ...
Xu F +6 more
europepmc +2 more sources
Ideological Tendencies in the Six English Qur’an Translation on Qs. Ar-Rum 41
Lessons from the Qur’an can be learned from its translation by those who do not understand Arabic, although the Qur’an does not state the meaning obviously.
Afif Suaidi, Moh Nur Arifin
doaj +1 more source
This article describes the state of progressive Qur'anic interpretation studies over the past five years at three State Islamic Higher Education, UIN Ar-Raniry Banda Aceh, UIN Imam Bonjol Padang and UIN Sultan Syarif Kasim Riau.
Maizuddin Maizuddin +1 more
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This research discusses KH Abdurrahman Wahid’s Qur’anic interpretation written in his articles around the 2002–2003 period. Initial studies of the text show that Gus Dur was only active in elaborating the Qur’anic verses in his articles after he stepped ...
Ahmad Ahnaf Rafif
doaj +1 more source
Cadar and Women’s Awrat In Indonesian Qur'an Literature
The use of cadar becomes a controversial discussion in Indonesia. However, the majority of scholars consider the cadar is not an obligation in religion. Bearing in mind, there are differences in the limits of women's genitalia or awrat.
Indal Abror +3 more
doaj +1 more source
A cross-tissue transcriptome-wide association study identifies novel susceptibility genes for atrial fibrillation. [PDF]
This cross‐tissue transcriptome‐wide association study identified five novel AF susceptibility genes (CAMK2D, SPAST2L, CEP68, FKBP7, and SHRMOO3). Elevated expression of FKBP7, CEP68, and CAMK2D increases AF risk, while SPATS2L shows a protective effect, with colocalization analysis implicating CEP68 and SPATS2L as prioritized candidates.
Yuan Y +4 more
europepmc +2 more sources
Buka Luwur as A Media of Education and Social Solidarity of Kudus Community
: Buka Luwur is an annual ritual that has become a tradition of Kudus community. It is a moment of respecting Kanjeng Sunan Kudus by providing some meal.
Irzum Farihah, Ismanto Ismanto
doaj +1 more source
Structural basis for the sequence-specific RNA-recognition mechanism of human CUG-BP1 RRM3 [PDF]
The CUG-binding protein 1 (CUG-BP1) is a member of the CUG-BP1 and ETR-like factors (CELF) family or the Bruno-like family and is involved in the control of splicing, translation and mRNA degradation.
Kanako Kuwasako +27 more
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