Results 1 to 10 of about 44,156 (145)

4E-BP1 counteracts human mesenchymal stem cell senescence via maintaining mitochondrial homeostasis

Protein & Cell, 2022
Although the mTOR-4E-BP1 signaling pathway is implicated in aging and aging-related disorders, the role of 4E-BP1 in regulating human stem cell homeostasis remains largely unknown.
Yifang He, Qianzhao Ji, Zeming Wu, Yusheng Cai, Jian Yin, Yiyuan Zhang, Sheng Zhang, Xiaoqian Liu, Weiqi Zhang, Guang-Hui Liu, Si Wang, Moshi Song, J. Qu   +12 more
semanticscholar   +1 more source

Fusarium BP1 is a reader of H3K27 methylation

Nucleic Acids Research, 2021
Histone H3 lysine 27 methylation catalyzed by polycomb repressive complex 2 (PRC2) is conserved from fungi to humans and represses gene transcription. However, the mechanism for recognition of methylated H3K27 remains unclear, especially in fungi.
G. Tang, Jianlong Yuan, Jing Wang, Yi-Zhe Zhang, Sijie Xie, Hongkai Wang, Zeng Tao, Huiquan Liu, H. Kistler, Youfu Zhao, Cheng-Guo Duan, Wende Liu, Zhonghua Ma, Yun Chen   +13 more
semanticscholar   +1 more source

BAP1 promotes viability and migration of ECA109 cells through KLF5/CyclinD1/FGF‐BP1

FEBS Open Bio, 2021
More than 40 000 patients worldwide die from esophageal cancer annually. The 5‐year survival rate of patients is only ~ 15–20%, and thus, there is an ongoing need to improve diagnosis and treatment of esophageal cancer.
Fengyun Wang, Ming Luo, Honglan Qu, Yufeng Cheng   +3 more
semanticscholar   +1 more source

Yeni Ad, Yeni Sayı, Yeni Web Sayfası ve Zengin İçerik

Cumhuriyet İlahiyat Dergisi, 2016
Akademik yayın hayatının 20. yılına ulaşan Cumhuriyet Üniversitesi İlahiyat Fakültesi Dergisi, son yıllarda ulusal ve uluslararası akademik yayıncılık alanında önemli mesafeler kat etti. 15 Aralık 2016 tarihinde yayımladığımız 19. cilt 2.
Ömer Aslan, Abdullah Demir
doaj   +2 more sources

Genomic, Clinical, and Behavioral Characterization of 15q11.2 BP1-BP2 Deletion (Burnside-Butler) Syndrome in Five Families

International Journal of Molecular Sciences, 2021
The 15q11.2 BP1-BP2 deletion (Burnside-Butler) syndrome is emerging as the most common cytogenetic finding in patients with neurodevelopmental or autism spectrum disorders (ASD) presenting for microarray genetic testing.
Isaac Baldwin, Robin L. Shafer, Waheeda A. Hossain, S. Gunewardena, Olivia J. Veatch, Matthew W. Mosconi, M. Butler   +6 more
semanticscholar   +1 more source

‘Akrâ-Halkâ Deyişi Özelinde Hz. Peygamberin Safiyye’ye Uğursuzluk Nisbetinin İmkanı Üzerine

Cumhuriyet İlahiyat Dergisi, 2020
Hadislerin doğru anlaşılması, dili iyi bilmenin yanı sıra sözün söylendiği ortam ve bağlam ile sözü söyleyenin kastını da bilebilmeyi gerektirir. Dilin içinde zamanla anlamı değişip gelişen sözcüklerin varlığının yanı sıra deyimsel kullanışları sebebiyle
Şule Yüksel Uysal
doaj   +1 more source

BAD regulates mammary gland morphogenesis by 4E-BP1-mediated control of localized translation in mouse and human models

Nature Communications, 2021
Elucidation of non-canonical protein functions can identify novel tissue homeostasis pathways. Herein, we describe a role for the Bcl-2 family member BAD in postnatal mammary gland morphogenesis.
J. M. Githaka, Namita Tripathi, Raven Kirschenman, Namrata Patel, V. Pandya, D. A. Kramer, Rachel Montpetit, Lin‐Fu Zhu, N. Sonenberg, R. Fahlman, N. Danial, D. Underhill, I. Goping   +12 more
semanticscholar   +1 more source

Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition.

JAMA psychiatry, 2020
Importance Recurrent microdeletions and duplications in the genomic region 15q11.2 between breakpoints 1 (BP1) and 2 (BP2) are associated with neurodevelopmental disorders.
D. van der Meer, I. Sønderby, T. Kaufmann, G. Walters, A. Abdellaoui, D. Ames, K. Amunts, M. Andersson, N. Armstrong, M. Bernard, Nicholas B. Blackburn, J. Blangero, D. Boomsma, H. Brodaty, R. Brouwer, R. Bülow, W. Cahn, V. Calhoun, S. Caspers, G. Cavalleri, C. Ching, S. Cichon, S. Ciufolini, A. Corvin, B. Crespo-Facorro, J. Curran, S. Dalvie, P. Dazzan, E. D. de Geus, G. D. de Zubicaray, S. D. de Zwarte, N. Delanty, Anouk den Braber, S. Desrivières, M. di Forti, J. Doherty, G. Donohoe, S. Ehrlich, E. Eising, T. Espeseth, S. Fisher, T. Fladby, O. Frei, V. Frouin, M. Fukunaga, Thomas Gareau, D. Glahn, H. Grabe, N. Groenewold, Ó. Gústafsson, J. Haavik, A. Håberg, R. Hashimoto, J. Hehir-Kwa, D. Hibar, M. Hillegers, P. Hoffmann, L. Holleran, J. Hottenga, H. H. Hulshoff Pol, M. Ikeda, S. Jacquemont, N. Jahanshad, C. Jockwitz, S. Johansson, E. Jönsson, M. Kikuchi, E. Knowles, J. Kwok, S. Le Hellard, D. Linden, Jingyu Liu, A. Lundervold, A. Lundervold, N. Martin, K. Mather, S. Mathias, K. Mcmahon, A. McRae, S. Medland, T. Moberget, C. Moreau, D. Morris, Thomas W. Mühleisen, R. Murray, J. Nordvik, L. Nyberg, Loes M. Olde Loohuis, R. Ophoff, M. Owen, T. Paus, Z. Pausova, J. Peralta, B. Pike, Carlos Prieto, E. Quinlan, C. Reinbold, T. Reis Marques, J. Rucker, P. Sachdev, S. Sando, P. Schofield, A. Schork, G. Schumann, Jean Shin, E. Shumskaya, Ana I. Silva, S. Sisodiya, V. Steen, Dan J Stein, Lachlan T. Strike, C. K. Tamnes, A. Teumer, A. Thalamuthu, D. Tordesillas-Gutiérrez, A. Uhlmann, M. Ulfarsson, D. van ‘t Ent, M. V. D. van den Bree, E. Vassos, W. Wen, K. Wittfeld, M. Wright, T. Zayats, A. Dale, S. Djurovic, I. Agartz, L. Westlye, H. Stefánsson, K. Stefánsson, P. Thompson, O. Andreassen   +131 more
semanticscholar   +1 more source

The 15q11.2 BP1-BP2 Microdeletion (Burnside–Butler) Syndrome: In Silico Analyses of the Four Coding Genes Reveal Functional Associations with Neurodevelopmental Disorders

International Journal of Molecular Sciences, 2020
The 15q11.2 BP1-BP2 microdeletion (Burnside–Butler) syndrome is emerging as the most frequent pathogenic copy number variation (CNV) in humans associated with neurodevelopmental disorders with changes in brain morphology, behavior, and cognition. In this
Syed K. Rafi, M. Butler
semanticscholar   +1 more source

Şâh Velî Ayıntâbî’nin el-Kevâkibü’l-Muzî’e fi’t-Tarîkati’l-Muhammediyye Adlı Risâlesi ve Tahlili: Üç Hadis Üç Hakikat

Cumhuriyet İlahiyat Dergisi, 2017
Bu çalışmada XVI. yüzyıl Halvetî şair ve mutasavvıflarından Şâh Velî Ayıntâbî’nin, el-Kevâkibü’l-Muzî’e fi’t-Tarîkati’l-Muhammediyye adlı risâlesi üzerinde durulmuştur. Risâle, müellifin yakaza halinde iken Hz.
Raşit Çavuşoğlu
doaj   +1 more source