A Bioengineered Stable Protein 1-Hemin Complex with Enhanced Peroxidase-Like Catalytic Properties. [PDF]
Peroxidase is a heme‐containing enzyme that has been broadly used in medical diagnosis, environmental treatments, and chemical syntheses. Its main limitation is low expression yields and poor stability in harsh environments. Herein, the feasibility and the use of Stable protein 1, a thermo‐stable and stress‐responsive protein, conjugated with hemin as ...
Zeibaq Y +4 more
europepmc +2 more sources
Mitochondrial ATP concentration decreases immediately after glucose administration to glucose-deprived hepatocytes. [PDF]
Hepatocytes can switch their metabolic processes in response to nutrient availability. We visualized metabolite dynamics in primary cultured hepatocytes during recovery from glucose‐deprivation. Glucose administration to hepatocytes under glucose deprivation conditions can cause an immediate decrease in the mitochondrial ATP concentration. In contrast,
Tsuno S +7 more
europepmc +2 more sources
Reinforcer value moderates response magnitude and persistence during extinction: A randomized trial. [PDF]
Abstract Extinction bursts, or temporary increases in rates and intensities of behavior during extinction, can preclude the inclusion of extinction in intervention packages meant to suppress severe challenging behavior. To identify underlying behavioral mechanisms responsible for response persistence and bursting, 69 adults with developmental ...
Lambert JM, Osina MA, Copeland BA.
europepmc +2 more sources
Flavonoids as Promising Akt1 Inhibitors in Cancer Medicine: Insights From Molecular Docking, Dynamics, DFT Calculations, and In Vitro Validation. [PDF]
ABSTRACT Background The PI3K/Akt/mTOR signaling pathway is commonly deregulated in different types of cancers, contributing to tumor proliferation, persistence, and resistance to treatment. Akt1, a crucial kinase within this pathway, plays a critical role in tumor progression and the occurrence of therapeutic resistance.
Jamshidi S +4 more
europepmc +2 more sources
Harnessing blue light photobiomodulation for cancer therapy: Evidence from a systematic review. [PDF]
Conventional treatments for various types of cancer are often associated with tumor recurrence and aggressiveness. Photobiomodulation with blue light (BL; 450–470 nm) emerges as a promising alternative with antitumor effects. This systematic review, with 37 in vitro and in vivo studies from 2002 to 2024, revealed that BL reduces cell viability ...
de Lima BES +6 more
europepmc +2 more sources
TELAAH PEMIKIRAN HADIS MAHMUD ABU RAYYAH DALAM BUKU “AḌWA’ ‘ALA AL-SUNNAH AL-MUHAMMADIYAH”
: In the development of contemporary hadith studies, especially after the time of Muhammad Abduh, a number of figures who appear to have a critical view of the classical era of hadith studies. Some people rate them as al-Sunnah inkār modern.
Sochimin Sochimin
doaj +3 more sources
MENGEMBANGKAN PERILAKU SEHAT MELALUI PENDEKATAN SOCIAL LEARNING THEORY
Prior to 1990s, the major cause of death is a cute disorder such as tuberculosis, small fox, leprosy and various infections convinced to be brought about by viruses and bacteria.
Fatimah Saguni
doaj +1 more source
MATURIDIYAH: KELAHIRAN DAN PERKEMBANGANNYA
In discourse of theological thought, the Matturidite and the Asy’arite popularly known as Ahl al-Sunnah wal al-Jama’ah, are two schools of Islamic theology that tried to take the middle path between the conservative theological thought and the rational ...
Hamka Hamka
doaj +1 more source
This research is library research that discusses the thought of Ibn Hazm. This research focuses on the study of the methodology of ijtihad of Ibn Hazm. One of the themes of ijtihad of Ibn Hazm can still, up to the present, be considered is his concept ...
Atik Wartini
doaj +1 more source
Polygamy is not introduced by Islam and neither does it promote sexuality. There are evidences that favour polygamy in different religions and nations before Islam, many Prophets have acceded to this.
Hafiz Muhammad Sani +2 more
doaj +1 more source

